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Volumn 12, Issue 11, 2010, Pages 2472-2475

A diversity-oriented synthesis of bicyclic cis -dihydroarenediols, cis -4-hydroxyscytalones, and bicyclic conduritol analogues

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; BICYCLO COMPOUND; CYCLOALKANE DERIVATIVE;

EID: 77952991732     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol100557f     Document Type: Article
Times cited : (24)

References (60)
  • 7
    • 77952992756 scopus 로고    scopus 로고
    • WO 0168071
    • Penco, S. WO 0168071, 2001.
    • (2001)
    • Penco, S.1
  • 8
    • 77953018642 scopus 로고    scopus 로고
    • note
    • During the course of our work, the controversy regarding the absolute stereochemistry of 3a was, however, settled by Hernandez-Galan et al.; see
  • 10
    • 77952978692 scopus 로고    scopus 로고
    • note
    • For the discussion of the conflicting biological profile of 3a in a larger context of its racemic synthesis, see
  • 42
    • 77953002982 scopus 로고    scopus 로고
    • Commercially available from Aldrich
    • Commercially available from Aldrich.
  • 43
    • 77952968419 scopus 로고    scopus 로고
    • Enantiomeric excess (ee) was determined by Mosher ester analysis; see
    • Enantiomeric excess (ee) was determined by Mosher ester analysis; see
  • 45
    • 77952960411 scopus 로고    scopus 로고
    • note
    • The relative and absolute configuration of this product is based on Barrett's work (14) and further confirmed by comparison of the sign of optical rotation of its derived cis -dihydroarenediol with those in the literature (see the Supporting Information).
  • 49
    • 77952985926 scopus 로고    scopus 로고
    • note
    • Prepared from commercially available 2-bromo-5-fluorobenzaldehyde by Stille reaction using tributylvinyltin reagent in 94% yield.
  • 50
    • 77952984055 scopus 로고    scopus 로고
    • note
    • Prepared from the corresponding alcohol (24) by oxidation with Collins reagent.
  • 55
    • 77953016777 scopus 로고    scopus 로고
    • note
    • Compound 19 was prepared from the reported lactone 18 (29) in three steps as follows
  • 57
    • 77952977716 scopus 로고    scopus 로고
    • note
    • The relative and absolute configuration of this diol is based on Barrett's work. (14)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.