-
1
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic HCV infection
-
3 December, 10.1126/science. 1178178
-
R. E. Lanford, E. S. Hildebrant-Eriksen, A. Petri, R. Persson, M. Lindow, M. E. Munk, S. Kauppinen, H. Orum, Therapeutic silencing of microRNA-122 in primates with chronic HCV infection. Science, 3 December 2009 (10.1126/science. 1178178).
-
(2009)
Science
-
-
Lanford, R.E.1
Hildebrant-Eriksen, E.S.2
Petri, A.3
Persson, R.4
Lindow, M.5
Munk, M.E.6
Kauppinen, S.7
Orum, H.8
-
2
-
-
59149101965
-
Optimal therapy in genotype 1 patients
-
H. Farnik, U. Mihm, S. Zeuzem, Optimal therapy in genotype 1 patients. Liver Int. 29 (suppl. 1), 23-30 (2009).
-
(2009)
Liver Int.
, vol.29
, Issue.SUPPL. 1
, pp. 23-30
-
-
Farnik, H.1
Mihm, U.2
Zeuzem, S.3
-
3
-
-
59149103099
-
Protease and polymerase inhibitors for the treatment of hepatitis C
-
T. Asselah, Y. Benhamou, P. Marcellin, Protease and polymerase inhibitors for the treatment of hepatitis C. Liver Int. 29 (suppl. 1), 57-67 (2009).
-
(2009)
Liver Int.
, vol.29
, Issue.SUPPL. 1
, pp. 57-67
-
-
Asselah, T.1
Benhamou, Y.2
Marcellin, P.3
-
4
-
-
70449559210
-
The quasispecies nature and biological implications of the hepatitis C virus
-
S. L. Fishman, A. D. Branch, The quasispecies nature and biological implications of the hepatitis C virus. Infect. Genet. Evol. 9, 1158-1167 (2009).
-
(2009)
Infect. Genet. Evol.
, vol.9
, pp. 1158-1167
-
-
Fishman, S.L.1
Branch, A.D.2
-
5
-
-
24644483623
-
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
-
C. L. Jopling, M. Yi, A. M. Lancaster, S. M. Lemon, P. Sarnow, Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309, 1577-1581 (2005).
-
(2005)
Science
, vol.309
, pp. 1577-1581
-
-
Jopling, C.L.1
Yi, M.2
Lancaster, A.M.3
Lemon, S.M.4
Sarnow, P.5
-
6
-
-
58049217312
-
MicroRNA-122 stimulates translation of hepatitis C virus RNA
-
J. I. Henke, D. Goergen, J. Zheng, Y. Song, C. G. Schüttler, C. Fehr, C. Jünemann, M. Niepmann, microRNA-122 stimulates translation of hepatitis C virus RNA. EMBO J. 27, 3300-3310 (2008).
-
(2008)
EMBO J.
, vol.27
, pp. 3300-3310
-
-
Henke, J.I.1
Goergen, D.2
Zheng, J.3
Song, Y.4
Schüttler, C.G.5
Fehr, C.6
Jünemann, C.7
Niepmann, M.8
-
7
-
-
46749124698
-
Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome
-
C. L. Jopling, S. Schütz, P. Sarnow, Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome. Cell Host Microbe 4, 77-85 (2008).
-
(2008)
Cell Host Microbe
, vol.4
, pp. 77-85
-
-
Jopling, C.L.1
Schütz, S.2
Sarnow, P.3
-
8
-
-
34548420660
-
Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus
-
J. Ye, Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus. PLoS Pathog. 3, e108 (2007).
-
(2007)
PLoS Pathog.
, vol.3
-
-
Ye, J.1
-
9
-
-
14044265120
-
Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids
-
S. B. Kapadia, F. V. Chisari, Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids. Proc. Natl. Acad. Sci. U.S.A. 102, 2561-2566 (2005).
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2561-2566
-
-
Kapadia, S.B.1
Chisari, F.V.2
-
10
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
J. Elmén, M. Lindow, S. Schütz, M. Lawrence, A. Petri, S. Obad, M. Lindholm, M. Hedtjärn, H. F. Hansen, U. Berger, S. Gullans, P. Kearney, P. Sarnow, E. M. Straarup, S. Kauppinen, LNA-mediated microRNA silencing in non-human primates. Nature 452, 896-899 (2008).
-
(2008)
Nature
, vol.452
, pp. 896-899
-
-
Elmén, J.1
Lindow, M.2
Schütz, S.3
Lawrence, M.4
Petri, A.5
Obad, S.6
Lindholm, M.7
Hedtjärn, M.8
Hansen, H.F.9
Berger, U.10
Gullans, S.11
Kearney, P.12
Sarnow, P.13
Straarup, E.M.14
Kauppinen, S.15
-
11
-
-
33846902312
-
Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals
-
E. E. Swayze, A. M. Siwkowski, E. V. Wancewicz, M. T. Migawa, T. K. Wyrzykiewicz, G. Hung, B. P. Monia, C. F. Bennett, Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals. Nucleic Acids Res. 35, 687-700 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 687-700
-
-
Swayze, E.E.1
Siwkowski, A.M.2
Wancewicz, E.V.3
Migawa, M.T.4
Wyrzykiewicz, T.K.5
Hung, G.6
Monia, B.P.7
Bennett, C.F.8
-
12
-
-
40249106014
-
Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver
-
J. Elmén, M. Lindow, A. Silahtaroglu, M. Bak, M. Christensen, A. Lind-Thomsen, M. Hedtjärn, J. B. Hansen, H. F. Hansen, E. M. Straarup, K. McCullagh, P. Kearney, S. Kauppinen, Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res. 36, 1153-1162 (2008).
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 1153-1162
-
-
Elmén, J.1
Lindow, M.2
Silahtaroglu, A.3
Bak, M.4
Christensen, M.5
Lind-Thomsen, A.6
Hedtjärn, M.7
Hansen, J.B.8
Hansen, H.F.9
Straarup, E.M.10
McCullagh, K.11
Kearney, P.12
Kauppinen, S.13
-
13
-
-
77951953925
-
Relationship of the use of statins and elevated Lowdensity Lipoprotein (LDL) or total cholesterol to virologic response in patients treated for HCV in the IDEAL study
-
S. Harrison, L. Rossaro, K.-Q. Hu, K. Patel, H. L. Tillmann, S. Dhaliwal, D. M. Torres, K. Koury, V. Goteti, C. A. Brass, S. Noviello, J. K. Albrecht, J. G. McHutchison, M. S. Sulkowski, Relationship of the use of statins and elevated lowdensity lipoprotein (LDL) or total cholesterol to virologic response in patients treated for HCV in the IDEAL study. Hepatology 50 (suppl. 4), 360A (2009).
-
(2009)
Hepatology
, vol.50
, Issue.SUPPL. 4
-
-
Harrison, S.1
Rossaro, L.2
Hu, K.-Q.3
Patel, K.4
Tillmann, H.L.5
Dhaliwal, S.6
Torres, D.M.7
Koury, K.8
Goteti, V.9
Brass, C.A.10
Noviello, S.11
Albrecht, J.K.12
McHutchison, J.G.13
Sulkowski, M.S.14
-
14
-
-
58149333128
-
Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy
-
M. Sarasin-Filipowicz, J. Krol, I. Markiewicz, M. H. Heim, W. Filipowicz, Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nat. Med. 15, 31-33 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 31-33
-
-
Sarasin-Filipowicz, M.1
Krol, J.2
Markiewicz, I.3
Heim, M.H.4
Filipowicz, W.5
-
15
-
-
0031978730
-
Human cytomegalovirus mutant with sequence-dependent resistance to the phosphorothioate oligonucleotide fomivirsen (ISIS 2922)
-
G. B. Mulamba, A. Hu, R. F. Azad, K. P. Anderson, D. M. Coen, Human cytomegalovirus mutant with sequence-dependent resistance to the phosphorothioate oligonucleotide fomivirsen (ISIS 2922). Antimicrob. Agents Chemother. 42, 971-973 (1998).
-
(1998)
Antimicrob. Agents Chemother
, vol.42
, pp. 971-973
-
-
Mulamba, G.B.1
Hu, A.2
Azad, R.F.3
Anderson, K.P.4
Coen, D.M.5
-
16
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
D. Ge, J. Fellay, A. J. Thompson, J. S. Simon, K. V. Shianna, T. J. Urban, E. L. Heinzen, P. Qiu, A. H. Bertelsen, A. J. Muir, M. Sulkowski, J. G. McHutchison, D. B. Goldstein, Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 461, 399-401 (2009).
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.J.3
Simon, J.S.4
Shianna, K.V.5
Urban, T.J.6
Heinzen, E.L.7
Qiu, P.8
Bertelsen, A.H.9
Muir, A.J.10
Sulkowski, M.11
McHutchison, J.G.12
Goldstein, D.B.13
-
17
-
-
70349533037
-
Genomewide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
-
Y. Tanaka, N. Nishida, M. Sugiyama, M. Kurosaki, K. Matsuura, N. Sakamoto, M. Nakagawa, M. Korenaga, K. Hino, S. Hige, Y. Ito, E. Mita, E. Tanaka, S. Mochida, Y. Murawaki, M. Honda, A. Sakai, Y. Hiasa, S. Nishiguchi, A. Koike, I. Sakaida, M. Imamura, K. Ito, K. Yano, N. Masaki, F. Sugauchi, N. Izumi, K. Tokunaga, M. Mizokami, Genomewide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat. Genet. 41, 1105-1109 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1105-1109
-
-
Tanaka, Y.1
Nishida, N.2
Sugiyama, M.3
Kurosaki, M.4
Matsuura, K.5
Sakamoto, N.6
Nakagawa, M.7
Korenaga, M.8
Hino, K.9
Hige, S.10
Ito, Y.11
Mita, E.12
Tanaka, E.13
Mochida, S.14
Murawaki, Y.15
Honda, M.16
Sakai, A.17
Hiasa, Y.18
Nishiguchi, S.19
Koike, A.20
Sakaida, I.21
Imamura, M.22
Ito, K.23
Yano, K.24
Masaki, N.25
Sugauchi, F.26
Izumi, N.27
Tokunaga, K.28
Mizokami, M.29
more..
-
18
-
-
70349548852
-
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
-
V. Suppiah, M. Moldovan, G. Ahlenstiel, T. Berg, M. Weltman, M. L. Abate, M. Bassendine, U. Spengler, G. J. Dore, E. Powell, S. Riordan, D. Sheridan, A. Smedile, V. Fragomeli, T. Müller, M. Bahlo, G. J. Stewart, D. R. Booth, J. George, IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat. Genet. 41, 1100-1104 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1100-1104
-
-
Suppiah, V.1
Moldovan, M.2
Ahlenstiel, G.3
Berg, T.4
Weltman, M.5
Abate, M.L.6
Bassendine, M.7
Spengler, U.8
Dore, G.J.9
Powell, E.10
Riordan, S.11
Sheridan, D.12
Smedile, A.13
Fragomeli, V.14
Müller, T.15
Bahlo, M.16
Stewart, G.J.17
Booth, D.R.18
George, J.19
-
19
-
-
73149113990
-
Public health impact of antiviral therapy for hepatitis C in the United States
-
M. L. Volk, R. Tocco, S. Saini, A. S. Lok, Public health impact of antiviral therapy for hepatitis C in the United States. Hepatology 50, 1750-1755 (2009).
-
(2009)
Hepatology
, vol.50
, pp. 1750-1755
-
-
Volk, M.L.1
Tocco, R.2
Saini, S.3
Lok, A.S.4
-
20
-
-
70349871321
-
MicroRNA expression, survival, and response to interferon in liver cancer
-
J. Ji, J. Shi, A. Budhu, Z. Yu, M. Forgues, S. Roessler, S. Ambs, Y. Chen, P. S. Meltzer, C. M. Croce, L. X. Qin, K. Man, C. M. Lo, J. Lee, I. O. Ng, J. Fan, Z. Y. Tang, H. C. Sun, X. W. Wang, MicroRNA expression, survival, and response to interferon in liver cancer. N. Engl. J. Med. 361, 1437-1447 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1437-1447
-
-
Ji, J.1
Shi, J.2
Budhu, A.3
Yu, Z.4
Forgues, M.5
Roessler, S.6
Ambs, S.7
Chen, Y.8
Meltzer, P.S.9
Croce, C.M.10
Qin, L.X.11
Man, K.12
Lo, C.M.13
Lee, J.14
Ng, I.O.15
Fan, J.16
Tang, Z.Y.17
Sun, H.C.18
Wang, X.W.19
|