Ameliorative effect of a combination of vitamin E, vitamin C, α- lipoic acid and stilbene resveratrol on lindane induced toxicity in mice olfactory lobe and cerebrum

Indian Journal of Experimental Biology

Volumn 48, Issue 2, 2010, Pages 150-158

  Bano, Mehajbeen ^a   Bhatt, Devendra Kumar ^a  

^a M L SUKHADIA UNIVERSITY   (India)

Author keywords

lipoic acid; Cerebrum; Lindane; Olfactory lobe; Stilbene resveratrol; Vitamin C; Vitamin E

Indexed keywords

MUS;

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CATALASE; CHOLESTEROL; CHOLINESTERASE; INSECTICIDE; LINDANE; NEUROPROTECTIVE AGENT; RESVERATROL; STILBENE DERIVATIVE; SUPEROXIDE DISMUTASE; THIOCTIC ACID;

ANIMAL; ARTICLE; BRAIN; CHILD; DRUG EFFECT; HISTOLOGY; HUMAN; INFANT; MALE; METABOLISM; MOUSE; OLFACTORY SYSTEM;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; BRAIN; BUTYRYLCHOLINESTERASE; CATALASE; CHILD; CHOLESTEROL; HUMANS; INFANT; INSECTICIDES; LINDANE; MALE; MICE; NEUROPROTECTIVE AGENTS; OLFACTORY PATHWAYS; STILBENES; SUPEROXIDE DISMUTASE; THIOCTIC ACID; VITAMIN E;

EID: 77952980558     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Pages N, Sauviat M P, Bouvet S,& Goudey-Perriere F, Different aspects of lindane toxicity: effect on reproduction, J de la Societe de Biologie, 196 (2002) 325.
2. Buck E D, Lachnit W G & Pessah I N, Mechanism of HCH toxicity: 1. Relationship between altered ventricular myocyte contractility and ryanodine receptor function, J Pharmacol Exp Therp, 289 (1999) 477.
3. Hall R C W & Hall R C W, Long term psychological and neurological complications of lindane poisoning, Psychomatics, 40 (1999) 513.
4. Singal M & Thami G P, Lindane neurotoxicity in childhood, Am J Therap, 13 (2006) 277.
5. Bano M & Bhatt D K, Neuroprotective role of a novel combination of certain antioxidants on lindane (γ-HCH) induced toxicity in cerebrum of mice, Res J Agric Biol Sci, 3 (2007) 664.
6. Gonzatlez-Rodriguez Cordoba J M, Cabanas-Espejo J M, Martinez Luque-Romero M & Mufioz-Blanco J, Alterations in acetylcholinesterase activity in plasma and synaptosomal fractions from CNS of rats acutely intoxicated with lindane, effect of succinylcholine, Bull Environ Contam Toxicol, 39 (1987) 647.
7. Mack A & Robitzki A, The key role of butyrylcholinesterase during neurogenesis and neural disorders: an antisense-5 butyrylcholinesterase-DNA study, Prog Neurobiol, 60 (2000) 607.
8. Cokugras A N, Butyrylcholinesterase: structure and physiological importance, Turk J Biochem, 28 (2003) 54.
9. Li B, Stribley J A, Ticu A, Xie W, Schopfer L M, Hammond P, Brijimion S, Hinrichs S H & Lockridge O, Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse, J Neurochem, 75 (2000)1320.
10. Tiwari R K, Bandyopadhay S K & Chatterjee G C, Protective effect of L ascorbic acid in lindane intoxicated rats, Acta Vitaminol Enzymol, 4 (1982) 215.
11. Podstawka V, Grabarezyk M & Kopee- szlezak J, Vitamin E protects human leucocytes against toxic effect of lindane in vitro, Mat Med Pol, 23 (1991) 285.
12. Srivastava A & Shivanandappa T, Hexachlorocyclohexane differentially alters the antioxidant status of the brain regions in rat, Toxicology, 214 (2006) 123.
13. Kontush A, Mann U, Arlt S, Vjeyl A, Lihrs C, Thomson T M & Beisiegel V, Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease, Free Rad Biol Med, 31 (2001) 345.
14. Gilguan-Sherki Y, Melamed E & Often D, Oxidative stress induced neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier, Neuropharm,40 (2001) 959.
15. Songsiri C, Bozena D L & Albert S, Amelioration of oxidative stress by antioxidants and resveratrol in PC 12 cells, Neuroreport, 8 (1997) 1499.
16. +ATPase in relation to its subcellular distribution in the brain, Acta Pharmacol Toxicol, 54 (1984) 299.
17. National Toxicology Programme (NTP), NTP chemical repository (Radiation Corporation, August 1991).lindane (58:89-90) 1998.
18. Karnovasky M J & Roots L A, Direct - colouring thiocholine method for cholinesterases, J Histochem Cytochem, 12 (1964) 217.
19. Ellman G L, Courtney K & Featherstone R, A new and rapid determination of acetylcholinesterase activity, Biochem Pharmacol, 7 (1961) 88.
20. Kakkar P, Das B & Viswanathan P N, A modified spectrophotometric assay of superoxide dismutase, Indian J Biochem Biophys, 21 (1984) 130.
21. Cohen G, Dembiec D & Marcus J, Measurement of catalase activity in tissue extracts, Anal Biochem,34 (1970) 30.
22. Lowry O H, Rosebrough N J, Farr A L & Randall R J, Protein measurement with the folin- phenol reagent. J Biol Chem, 193 (1951) 265.
23. Oser B L, Hawks physiological chemistry, (Mc Graw Hill, New York) 1965, 26.
24. Cajal Ramony S R, Studies on the cerebral cortex (Lloyd-Luke, London) 1955.
25. Gerr F, Health effects of exposures to neurotoxic agents used in the Persian Gulf War. A report to the Committee on Veterans' Affairs of the United States Senate. 325 (1998).
26. Sinha C & Shukla G S, Species variation in pesticide induced blood brain barrier dysfunction, Hum Exp Toxicol, 22 (2003) 647.
27. Sanfeliu C, Camon L, Martinez E, Solà F & Rodríguez-Farré E, Regional distribution of lindane in rat brain, Toxicology, 49 (1988) 189.
28. Videla L A, Barros S B & Janqueria V B, Lindane induced liver oxidative stress. Free Raddic Biol Med, 9 (1990) 169.
29. Sahoo A & Chainy G B N, Acute hexachlorocyclohexaneinduced oxidative stress in rat cerebral hemisphere, Neuorchem Res, 23 (1998) 1079.
30. Ananya R, Subeena S, Kumar D A, Kumar D T & Kumar S M, Oxidative stress and histopathological changes in the heart following oral lindane (γ-HCH) administration in rats, Med Sci Monit,11 (2005) 325.
31. Mann H, McCoy M T, Subramaniam J, Remmen H V & Cadet J L, Overexpression of superoxide dismutase and catalase in immortalized neural cells: toxic effects of hydrogen peroxide, Brain Res, 770 (1997) 163.
32. Prabhakaran S & Devi K S, Impact of protein deficiency and exposure to HCH or malathione on lipid metabolism in pregnant rats. Indian J Biochem Biophys, 30 (1993) 234.
33. Carrero I, Prieto J C, Recio M N, Del H N & Perez-Albarsanz M A, The diverse actions of lindane in rat enterocytes: interactions with lipid metabolism and membrane fluidity, Pestic Biochem Physiol, 47 (1993) 69.
34. Hamilton P B, Toxic overload, in Health and Fittness, (2005) 277.
35. Chow C K, Vitamin E regulation of mitochondrial superoxide generation, Biol Signal Recept, 10 (2001) 112.
36. Butterfield D A, Castegna A, Drake J & Scapagnini Calabrese V, Vitamin E and neurodegenerative disorders associated with oxidative stress, Nutr Neurosci,5 (2002) 229.
37. Kagan V E, Kuzmeko A I, Shvedova A A, Kisin E, Li R,Martin I, Quinn P J, Tyurin V A, Tyurina Y Y & Yalowich J C, Direct evidence for recycling of myeloperoxidase catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells, Biochem Biophys Acta, 1620 (2003) 72.
38. Padh H, Cellular functions of ascorbic acid, Biochem Cell Biol, 68 (1990) 1163.
39. Augs D B, Sanjiu S G, Pardridge W M, Spielholz C, Baselga J, Carlos V J & Golde D W, Vitamin C crosses the BBB in the oxidized form through the glucose transporters, J Clin Invest, 100 (1997) 2842.
40. Packer L, Witt E H & Tritschler H J, Alpha-lipoic acid as a biological antioxidant, Free Radic Biol Med, 19 (1995) 227.
41. Stoyanovsky D A, Goldman R, Darrow R M, Organisciak D T & Kagan V E, Endogenous ascorbate regenerates Vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid, Curr Eye Res, 14 (1995) 181.
42. Mokini M, Elkahoui S, Liman F, Amri M & Aouani E, Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat, Neurochem Res, 32 (2007) 981.
43. Sinha K, Chaudhary G & Gupta Y K, Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats, Life Sci, 71 (2002) 655.
44. Virgili M & Contestabile P A, Neuroprotection of in vivo excitotoxic brain damage by chronic administration of red wine antioxidants agent, trans resveratrol in rats, Neuroscience Letters, 281 (2000) 123.