Extensive autolytic fragmentation of membranous versus cytosolic calpain following myocardial ischemia-reperfusion

Canadian Journal of Physiology and Pharmacology

Volumn 88, Issue 5, 2010, Pages 584-594

  Gilchrist, James S C ^a   Cook, Tom ^a   Abrenica, Bernard ^a   Rashidkhani, Babak ^a   Pierce, Grant N ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Calcium; Calpain; Heart; Ischemia reperfusion; Protease

Indexed keywords

ALPHA FODRIN; CALPAIN; CALPASTATIN; ION CHANNEL; MEMBRANE PROTEIN; PEPTIDE; RYANODINE RECEPTOR 2; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; ACETYLLEUCYL-LEUCYL-NORLEUCINAL; LEUPEPTIN; N-ACETYLLEUCYL-LEUCYL-METHIONINAL; OLIGOPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOLYSIS; CONTROLLED STUDY; DEGRADATION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; MALE; MOLECULAR WEIGHT; MUSCLE FIBRIL; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOLEMMA; SARCOPLASMIC RETICULUM; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL FRACTIONATION; CYTOSOL; DISEASE MODEL; DOG; HEART MUSCLE; INTRACELLULAR MEMBRANE; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PATHOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; RABBIT; SKELETAL MUSCLE; SPRAGUE DAWLEY RAT;

ANIMALS; AUTOLYSIS; BLOTTING, WESTERN; CALPAIN; CELL FRACTIONATION; CYTOSOL; DISEASE MODELS, ANIMAL; DOGS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; INTRACELLULAR MEMBRANES; LEUPEPTINS; MALE; MUSCLE, SKELETAL; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; OLIGOPEPTIDES; RABBITS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77952919818     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y10-031     Document Type: Article

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