In vitro studies of multiwalled carbon nanotube/ultrahigh molecular weight polyethylene nanocomposites with osteoblast-like MG63 cells

Brazilian Journal of Medical and Biological Research

Volumn 43, Issue 5, 2010, Pages 476-482

  Reis, J ^a   Kanagaraj, S ^b   Fonseca, A ^c   Mathew, M T ^d   Capela Silva, F ^a   Potes, J ^a   Pereira, A ^a   Oliveira, M S A ^c   Simoes J A ^c  

^a UNIVERSITY OF ÉVORA   (Portugal)

^b INDIAN INSTITUTE OF TECHNOLOGY GUWAHATI   (India)

^c UNIVERSITY OF AVEIRO   (Portugal)

^d RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Carbon nanotubes; MG63 cells; Nanocomposites; Orthopedic; Osteoblast; Wear particle

Indexed keywords

INTERLEUKIN 6; MULTI WALLED NANOTUBE; NANOCOMPOSITE; ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE;

ACETABULUM; ARTICLE; BIOCOMPATIBILITY; CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; HIP ARTHROPLASTY; HUMAN; HUMAN CELL; IN VITRO STUDY; OSTEOBLAST; OSTEOLYSIS; PARTICLE SIZE; TREATMENT FAILURE;

EID: 77952905232     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2010007500038     Document Type: Article

References (39)

1. Supronowicz PR, Ajayan PM, Ullmann KR, Arulanandam BP, Metzger DW, Bizios R. Novel current-conducting composite substrates for exposing osteoblasts to alternating current stimulation. J Biomed Mater Res 2002; 59: 499-506.
2. Cherukuri P, Bachilo SM, Litovsky SH, Weisman RB. Near- infrared fluorescence microscopy of single-walled carbon nanotubes in phagocytic cells. J Am Chem Soc 2004; 126: 15638-15639.
3. Bianco A, Kostarelos K, Prato M. Applications of carbon nanotubes in drug delivery. Curr Opin Chem Biol 2005; 9: 674-679.
4. Liu Z, Cai W, He L, Nakayama N, Chen K, Sun X, et al. In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat Nanotechnol 2007; 2: 47-52
5. Koerner H, Price G, Pearce NA, Alexander M, Vaia RA. Remotely actuated polymer nanocomposites stress-recovery of carbon-nanotube-filled thermoplastic elastomers. Nat Mater 2004; 3: 115-120.
6. Sen R, Zhao B, Perea D, Itkis ME, Hu H, Love J, et al. Preparation of single-walled carbon nanotube reinforced polystyrene and polyurethane nanofibers and membranes by electrospinning. Nano Lett 2004; 4: 459-464.
7. Gomez-Barrena E, Puertolas JA, Munuera L, Konttinen YT. Update on UHMWPE research: from the bench to the bed- side. Acta Orthop 2008; 79: 832-840.
8. Kanagaraj S, Varanda FR, Zhil'tsova TV, Oliveira MSA, Simões JAO. Mechanical properties of high density polyethylene/carbon nanotube composites. Compos Sci Technol 2007; 67: 3071-3077.
9. Chlopek J, Czajkowska B, Szaraniec B, Frackowiak E, Szostak K, Béguin F. In vitro studies of carbon nanotubes biocompatibility. Carbon 2006; 44: 1106-1111.
10. Meng J, Kong H, Han Z, Wang C, Zhu G, Xie S, et al. Enhancement of nanofibrous scaffold of multiwalled carbon nanotubes/polyurethane composite to the fibroblasts growth and biosynthesis. J Biomed Mater Res A 2009; 88: 105-116
11. Sitharaman B, Shi X, Walboomers XF, Liao H, Cuijpers V, Wilson LJ, et al. In vivo biocompatibility of ultra-short single-walled carbon nanotube/biodegradable polymer nanocomposites for bone tissue engineering. Bone 2008; 43: 362-370.
12. Lam CW, James JT, McCluskey R, Hunter RL. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol Sci 2004; 77: 126-134.
13. Muller J, Huaux F, Moreau N, Misson P, Heilier JF, Delos M, et al. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol Appl Pharmacol 2005; 207: 221-231.
14. Shvedova AA, Kisin ER, Mercer R, Murray AR, Johnson VJ, Potapovich AI, et al. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am J Physiol Lung Cell Mol Physiol 2005; 289: L698-L708
15. Jia G, Wang H, Yan L, Wang X, Pei R, Yan T, et al. Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene. Environ Sci Technol 2005; 39: 1378-1383.
16. Magrez A, Kasas S, Salicio V, Pasquier N, Seo JW, Celio M, et al. Cellular toxicity of carbon-based nanomaterials. Nano Lett 2006; 6: 1121-1125.
17. Davoren M, Herzog E, Casey A, Cottineau B, Chambers G, Byrne HJ, et al. In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells. Toxicol In Vitro 2007; 21: 438-448.
18. Zhang LW, Zeng L, Barron AR, Monteiro-Riviere NA. Biological interactions of functionalized single-wall carbon nanotubes in human epidermal keratinocytes. Int J Toxicol 2007; 26: 103-113.
19. Tian F, Cui D, Schwarz H, Estrada GG, Kobayashi H. Cytotoxicity of single-wall carbon nanotubes on human fibroblasts. Toxicol In Vitro 2006; 20: 1202-1212.
20. Mercer RR, Scabilloni J, Wang L, Kisin E, Murray AR, Schwegler-Berry D, et al. Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model. Am J Physiol Lung Cell Mol Physiol 2008; 294: L87-L97
21. Pulskamp K, Diabate S, Krug HF. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol Lett 2007; 168: 58-74.
22. Cui D, Tian F, Ozkan CS, Wang M, Gao H. Effect of single wall carbon nanotubes on human HEK293 cells. Toxicol Lett 2005; 155: 73-85.
23. Monteiro-Riviere NA, Nemanich RJ, Inman AO, Wang YY, Riviere JE. Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol Lett 2005; 155: 377-384
24. Sayes CM, Liang F, Hudson JL, Mendez J, Guo W, Beach JM, et al. Functionalization density dependence of single- walled carbon nanotubes cytotoxicity in vitro. Toxicol Lett 2006; 161: 135-142.
25. Dumortier H, Lacotte S, Pastorin G, Marega R, Wu W, Bonifazi D, et al. Functionalized carbon nanotubes are non- cytotoxic and preserve the functionality of primary immune cells. Nano Lett 2006; 6: 1522-1528.
26. Brown DM, Kinloch IA, Bangert U, Windle AH, Walter DM, Walker GS, et al. An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis. Carbon 2007; 45: 1743-1756.
27. Fraczek A, Menaszek E, Paluszkiewicz C, Blazewicz M. Comparative in vivo biocompatibility study of single- and multi-wall carbon nanotubes. Acta Biomater 2008; 4: 1593-1602.
28. Poland CA, Duffin R, Kinloch I, Maynard A, Wallace WA, Seaton A, et al. Carbon nanotubes introduced into the ab- dominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 2008; 3: 423-428.
29. +/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 2008; 33: 105-116.
30. Lacerda L, Ali-Boucetta H, Herrero MA, Pastorin G, Bianco A, Prato M, et al. Tissue histology and physiology following intravenous administration of different types of functionalized multiwalled carbon nanotubes. Nanomedicine 2008; 3: 149-161.
31. Schipper ML, Nakayama-Ratchford N, Davis CR, Kam NW, Chu P, Liu Z, et al. A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice. Nat Nanotechnol 2008; 3: 216-221.
32. Deng X, Jia G, Wang H, Sun H, Wang X, Yang S, et al. Translocation and fate of multi-walled carbon nanotubes in vivo. Carbon 2007; 45: 1419-1424.
33. Fonseca A, Inacio N, Kanagaraj S, Oliveira MSA, Simoes JAO. The use of Taguchi technique to optimize the compression moulding cycle to process acetabular cups components. J Nanosci Nanotechnol 2010 (in press)
34. Green TR, Fisher J, Stone M, Wroblewski BM, Ingham E. Polyethylene particles of a 'critical size' are necessary for the induction of cytokines by macrophages in vitro. Biomaterials 1998; 19: 2297-2302.
35. Casey A, Herzog E, Davoren M, Lyng FM, Byrne HJ, Chambers G. Spectroscopic analysis confirms the interactions between single walled carbon nanotubes and various dyes commonly used to assess cytotoxicity. Carbon 2007; 45: 1425-1432.
36. Ishimi Y, Miyaura C, Jin CH, Akatsu T, Abe E, Nakamura Y, et al. IL-6 is produced by osteoblasts and induces bone resorption. J Immunol 1990; 145: 3297-3303.
37. Bosetti M, Zanardi L, Bracco P, Costa L, Cannas M. In vitro evaluation of the inflammatory activity of ultra-high molecular weight polyethylene. Biomaterials 2003; 24: 1419-1426.
38. Guo L, Von Dem BA, Buechner M, Yan A, Kane AB, Hurt RH. Adsorption of essential micronutrients by carbon nanotubes and the implications for nanotoxicity testing. Small 2008; 4: 721-727.
39. Narita N, Kobayashi Y, Nakamura H, Maeda K, Ishihara A, Mizoguchi T, et al. Multiwalled carbon nanotubes specifi- cally inhibit osteoclast differentiation and function. Nano Lett 2009; 9: 1406-1413.