Blood-brain barrier transport of drug-loaded nanoparticle: Research advances

Journal of International Pharmaceutical Research

Volumn 37, Issue 1, 2010, Pages 40-42

  Wang, Bin Yan ^a   Xia, Ai Xiao ^a   Chen, Ping Ping ^a   Ni, Ling ^a   Liu, Fu He ^a   Li, Fan Zhu ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Blood brain barrier; Central nervous system agents; Drug carrier; Nanoparticle

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN E; BOVINE SERUM ALBUMIN; DRUG; DRUG CARRIER; ENBUCRILATE; GLYCOPROTEIN P; LOW DENSITY LIPOPROTEIN; NANOPARTICLE;

BLOOD BRAIN BARRIER; BRAIN TISSUE; CENTRAL NERVOUS SYSTEM; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RESEARCH; DRUG TRANSPORT; ENDOCYTOSIS; HOMEOSTASIS; HUMAN; NEUROPROTECTION; REVIEW;

EID: 77952900358     PISSN: 16740440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (19)

1. Kreuter J, Alyautolin RN, Kharkevieh DA, et al. Passage of peptides through the blood-brain barrier with colloidal polymer particles(nanoparticles) [J]. Brain Res, 1995, 67 4(1): 171-174.
2. Kreuter J. Nanoparticle systems for brain delivery of drugs [J]. Adv Drug Deliv Rev, 2001, 47:65-81. (Pubitemid 32209233)
3. Kreuter J. Transport of drugs across the blood-brain barrier by nanoparitcles[J]. Curr Med Chem CNS Agents, 2002, 2(3): 241-249. (Pubitemid 36267728)
4. Kreuter J. Swarbrcik JC, et al. Encyclopedia of pharmaceutical technology[M]. Third Edition-6 Volume Set(Print). Dekker, New York:Marcel, 1994:165-190.
5. Sun W, Xie C, Wang H, et al. Specific role of polysorbate-80-coated on the targeting of nanoparticles to the brain [J]. Biomaterials, 2004, 25(15):3065-3071. (Pubitemid 38210199)
6. Kreuter J, Shamenkov D, Petrov V, et al. Apolipoprotein-media-mediated transport of nanoparticle-bound drugs across the blood-brain barrier[J]. J Drug Target, 2002, 10(4):317-325. (Pubitemid 34746313)
7. Michaelis K, Hoffmann MM, Dreis S, et al. Covalent linkage of apolipoprotein E to albumin nanoparticles strongly enhances drug transport into the brain[J] . J Pharmacol Exp Ther, 2006, 317 (3):1246-1253. (Pubitemid 43764130)
8. Kim HR, Gil S, Andrieux K, et al. Low-density ipoprotein receptor-mediated endocytosis of pegylated nanoparticles in rat brain endothelial cells [J]. Cell Mol Life Sci, 2007, 64(3): 356-364. (Pubitemid 46440206)
9. Kreuter J, Hekmatara T, Dreis S, et al. Covalent attachment of apolipoprotein A-I and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain [J]. J Controlled Release, 2007, 118(1):54-58.
10. Beduneau A, Saulnier P, Benoit JP. Active targeting of brain tumors using nanocarriers [J]. Biomaterials, 2007, 28(33); 4947-4967. (Pubitemid 47362345)
11. Vinogradov SV, Batrakova EV, Kabanov AV. Nanogels for oligonucleotide delivery to the brain[J]. Bioconjug Chem, 2004, 15 (1):50-60.
12. Lu W, Tan YZ, Hu KL, et al. Cationic albumin conjugated pegylated nanoparticle with its transcytosis ability and little toxicity against blood-brain barrier[J]. Int J Pharm, 2005, 295(1/2): 247-260. (Pubitemid 40558807)
13. Lu W, Wan J, Zhang Q, et al. Aclarubicin-loaded cationic albumin-conjugated pegylated nanoparticle for glioma chemotherapy in rats [J]. Int J Cancer, 2007, 120(2):420-431. (Pubitemid 44956856)
14. Schroeder U, Sommerfeld P, Ulrich S, et al. Nanoparticle technology for delivery of drugs across the blood-brain barrier[J]. J Pharm Sci, 2001, 87(11):1305-1307.
15. Koziara JM, Lockman PR, Alen DD, et al. Paclitaxel nanoparticles for the potential treatment of brain tumors[J]. J Controlled Release, 2004, 99(2):259-269. (Pubitemid 39222111)
16. Batrakova EV, Li S, Vinogradov. SV, et al. Mechanism of pluronic effect on p-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization [J]. J Pharmacol Exp Ther, 2001, 299(2):483-493.
17. Olivier JC, Fenart L, Chauvet R, et al. Indirect evidence that drug brain targeting using polysorbate-80-coated polybutylcyanoacrylate nanoparticles is related to toxicity [J]. Pharm Res, 1999, 16(12):1836-1842. (Pubitemid 30040699)
18. Gessner A, Olbrich C, Schroder W, et al. The role of plasma proteins in brain targeting: species dependent protein adsorption patterns on brain-specific lipid drug conjugate (LDC) nanoparticles[J]. Int J Pharm, 2001, 214(1/2):87-91. (Pubitemid 32244084)
19. Ambruosi A, Gelperina S, Khalansky A, et al. Influence of surfactants, polymer and doxorubicin loading on the antitumour effect of polybutylcyanoacrylate nanoparticles in a rat glioma model [J]. J Microencapsul, 2006, 23(5):582-592. (Pubitemid 44446597)