Integrating lys-n proteolysis and n-terminal guanidination for improved fragmentation and relative quantification of singly-charged ions

Journal of the American Society for Mass Spectrometry

Volumn 21, Issue 6, 2010, Pages 1050-1060

  Carabetta, Valerie J ^a   Li, Tuo ^a   Shakya, Anisha ^a   Greco, Todd M ^a   Cristea, Ileana M ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROTEINS; CHARGED IONS; COMPLEMENTARY PROTEINS; E. COLI; FRAGMENTATION EFFICIENCY; FRAGMENTATION PATTERNS; ISOTOPE LABELING; MALDI MS/MS; MALDI-MASS SPECTROMETRY; N-TERMINALS; PEPTIDE SEQUENCES; POLYADENYLATION; PROTEIN COMPLEXES; PROTEIN INTERACTION; PROTEIN SEQUENCES; PROTEOMIC ANALYSIS; PROTEOMIC STUDIES; RELATIVE ABUNDANCE; RELATIVE QUANTIFICATION; TANDEM MS; TRYPSIN DIGESTION; TRYPTIC PEPTIDES;

COMPLEXATION; ESCHERICHIA COLI; ISOTOPES; MASS SPECTROMETRY;

PEPTIDES;

ACTIN RELATED PROTEIN 2; BACTERIAL PROTEIN; LYSINE; PROTEIN PAP I; TRYPSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; ESCHERICHIA COLI; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION MASS SPECTROMETRY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SENSITIVITY AND SPECIFICITY; SURFACE CHARGE; TANDEM MASS SPECTROMETRY; YEAST;

ACTIN-RELATED PROTEIN 2; AMINO ACID SEQUENCE; ESCHERICHIA COLI PROTEINS; GUANIDINE; LYSINE; METALLOENDOPEPTIDASES; METHYLUREA COMPOUNDS; NITROGEN ISOTOPES; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PROTEOMICS; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY; TRYPSIN;

EID: 77952883912     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2010.02.004     Document Type: Article

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