Antioxidant capability and efficacy of Mega-H™ silica hydride, an antioxidant dietary supplement, by in vitro cellular analysis using photosensitization and fluorescence detection

Journal of Medicinal Food

Volumn 5, Issue 1, 2002, Pages 9-16

  Stephanson, Cory J ^a   Stephanson, Anne M ^b   Flanagan, G Patrick ^c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b NORTHWESTERN HEALTH SCIENCES UNIVERSITY   (United States)

^c Flantech Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FREE RADICAL; HYDROXYL RADICAL; MEGA H; REACTIVE OXYGEN METABOLITE; SCAVENGER; SILICON DERIVATIVE; SILICON DIOXIDE; SINGLET OXYGEN; SUPEROXIDE; ANTIOXIDANT; COLORING AGENT; FLUORESCENT DYE; FUCHSINE; MALACHITE GREEN; OXYGEN; ROSE BENGAL;

ANALYTIC METHOD; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL MEMBRANE; CELL VIABILITY; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; DIET SUPPLEMENTATION; DRUG EFFICACY; ENZYME ACTIVITY; HYBRIDOMA CELL CULTURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHOTOSENSITIZATION; PRIORITY JOURNAL; SPECTROFLUOROMETRY; ANIMAL; CELL SURVIVAL; CYTOLOGY; FLUORESCENCE MICROSCOPY; HAMSTER; HYBRIDOMA; METABOLISM; OXIDATION REDUCTION REACTION; PHOTOCHEMISTRY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; SIPROETA STELENES;

ANIMALS; ANTIOXIDANTS; CELL SURVIVAL; CHO CELLS; COLORING AGENTS; CRICETINAE; DIETARY SUPPLEMENTS; FLUORESCENT DYES; HYBRIDOMAS; HYDROXYL RADICAL; MICE; MICROSCOPY, FLUORESCENCE; OXIDATION-REDUCTION; OXYGEN; PHOTOCHEMISTRY; REACTIVE OXYGEN SPECIES; ROSANILINE DYES; ROSE BENGAL; SILICON DIOXIDE; SINGLET OXYGEN; SPECTROMETRY, FLUORESCENCE;

EID: 0036011230     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/109662002753723179     Document Type: Article

References (37)

1. Oxidative stress and antioxidant response during exercise
2. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
3. Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite
4. Biochemistry and pathology of radical mediated protein oxidation
5. Oxidative stress: Adaptation, damage, repair, and death
6. Myocardial aging: Antioxidant enzyme system and related biochemical properties
7. Inactivation of sunflower NADH: Nitrate reductase by white light-activated rose bengal
8. Characterization of antioxidant properties of natural killer-enhancing factor-B and induction of its expression by hydrogen peroxide
9. Nutrient supply and mitochondrial function
10. Activation of thiol-dependent antioxidant activity of human serum albumin by alkaline pH is due to the B-like conformational change
11. A silicate mineral supplement, Microhydrin®, traps reduced hydrogen providing in vitro biological antioxidant properties
12. Silica and aluminum in drinking water and cognitive impairment in the elderly
13. Chemical analysis of water used in Hunza, Pakistan
14. Evidence of stable hydrides in an aqueous solution using modern analytical techniques
15. Studies of oxidation-reduction: II. An analysis of the relations between reduction potential and pH
16. Sensitive spectrophotometric determination of formaldehyde by inhibition of the malachite green-sulfite reaction
17. L-Selectin signaling of neutrophil adhesion and degranulation involves p38 mitogen-activated protein kinase
18. Quantification of total oxidant scavenging capacity of antioxidants for peronitrite, peroxyl radicals, and hydroxyl radicals
19. Photomodification of the electrical properties of the plasma membrane: A comparison between 6 different membrane-active photosensitizers
20. 2)
21. The specificity and product of quenching singlet oxygen by 2,2,6,6-tetramethylpiperidine
22. Oxygen-radical absorbance capacity assay for antioxidants
23. Evaluation of antioxidant activity by chemiluminescence
24. Photodynamic therapy-induced death of mcf-7 human breast cancer cells: A role for caspase-3 in the late steps of apoptosis but not for the critical lethal event
25. A fluorescence-based method for measuring total plasma antioxidant capability
26. Enzyme-assisted cell photosensitization: A proposal for an efficient approach to tumor therapy and diagnosis. The rose bengal fluorogenic substrate
27. Colorimetric determination of sulfuric dioxide in air using a droplet collector of malachite green solution
28. Malignant transformation of Syrian hamster embryo (SHE) cells in primary culture by malachite green: Transformation is associated with abrogation of G2/M checkpoint control
29. CH3 cells, ionic currents and cell killing: Photomodification sensitized by rose bengal
30. Local endostatin treatment of gliomas administered by microencapsulated producer cells
31. Neuronal death is an active, caspase-dependent process after moderate but not severe DNA damage
32. Equilibrium and kinetic measurements of muscarinic receptor antagonism on living cells using bead injection spectroscopy
33. Import of firefly luciferase into peroxisomes of permeabilized Chinese hamster ovary cells: A model system to study peroxisomal protein import in vitro
34. Expression of the 6C3 antigen on murine hematopoietic neoplasms: Association with expression of abl, ras, fes, src, rbB, and Cas NS-1 oncogenes but not with myc
35. DNA damage vs. cell killing by low-dose-rate gamma radiation ultrasensitive measures, and implications for mechanistically modeled cancer risk