Application of the comet assay for assessment of oxidative DNA damage in circulating lymphocytes of Tetralogy of Fallot patients

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 688, Issue 1-2, 2010, Pages 62-65

  Srujana, Kola ^a   Begum, Syed Sunayana ^a   Rao, Koneti Nageswara ^b   Devi, Gundimeda Sandhya ^a   Jyothy, Akka ^a   Prasad, Mundluru Hema ^a  

^a OSMANIA UNIVERSITY   (India)

^b CARE HOSPITAL   (India)

Author keywords

Comet assay; Hypoxia; Oxidative DNA damage; Tetralogy of Fallot

Indexed keywords

ANTIOXIDANT; DNA; OXIDIZING AGENT; SILVER;

ADOLESCENT; ARTICLE; CASE CONTROL STUDY; CELL NUCLEUS; CHILD; COMET ASSAY; CONTROLLED STUDY; CYANOSIS; DISEASE ASSOCIATION; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; FALLOT TETRALOGY; FEMALE; HUMAN; HUMAN CELL; HYPOXIA; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE; PRESCHOOL CHILD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCHOOL CHILD; SENSITIVITY ANALYSIS; SINGLE STRANDED DNA BREAK; TWO DIMENSIONAL ECHOCARDIOGRAPHY;

ADOLESCENT; ANOXIA; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; COMET ASSAY; DNA DAMAGE; HUMANS; OXIDATIVE STRESS; TETRALOGY OF FALLOT;

EID: 77952878667     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2010.03.009     Document Type: Article

References (30)

1. Hoffman J.I., Kaplan S. The incidence of congenital heart disease. J. Am. Coll. Cardiol. 2002, 39:1890-1900.
2. Botto L.D., Khoury M.J., Mulinare J., Erickson J.D. Periconceptional multivitamin use and the occurrence of conotruncal heart defects: results from a population-based, case-control study. Pediatrics 1996, 98:911-917.
3. Wernovsky G, Mayer J.E., Jonas R.A., Hanley F.L., Blackstone E.H., Kirklin J.W., Castañeda A.R. Factors influencing early and late outcome of the arterial switch operation for transposition of the great arteries. J. Thorac. Cardiovasc. Surg. 1995, 109:289-301.
4. Li R.K., Mickle D.A., Weisel R.D., Tumiati L.C., Jackowski G., Wu T.W., Williams W.G. Effect of oxygen tension on the anti-oxidant enzyme activities of Tetralogy of Fallot ventricular myocytes. J. Mol. Cell. Cardiol. 1989, 21:567-575.
5. Rokicki W., Strzałkowski A., Kłapcińska B., Danch A., Sobczak A. Antioxidant status in newborns and infants suffering from congenital heart defects. Wiad. Lek. 2003, 56:337-340.
6. Bogie R.G., Coade S.B., Moncada S., Pearson J.D., Mann G.E. Bradykinin and ATP stimulate l-arginine uptake and nitric oxide release in vascular endothelial cells. Biochem. Biophys. Res. Commun. 1991, 180:926-932.
7. Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantification of low levels of DNA damage in individual cells. Exp. Cell Res. 1988, 175:184-191.
8. Nadin S.B., Vargas-Roig L.M., Ciocca D.R. A silver staining method for single-cell gel assay. J. Histochem. Cytochem. 2001, 49:1183-1186.
9. Zana M., Szécsényi A., Czibula A., Bjelik A., Juhász A., Rimanóczy A., Szabó K., Vetró A., Szucs P., Várkonyi A., Pákáski M., Boda K., Raskó I., Janka Z., Kálmán J. Age dependent oxidative stress induced DNA damage in Down's lymphocytes. Biochem. Biophys. Res. Commun. 2006, 345:726-733.
10. Morawiec Z., Janik K., Kowalski M., Stetkiewicz T., Szaflik J., Morawiec-Bajda A., Sobczuk A., Blasiak J. DNA damage and repair in children with Down's syndrome. Mutat. Res. 2008, 637:118-123.
11. Tsui H.C., Wu H.D., Lin C.J., Wang R.Y., Chiu H.T., Cheng Y.C., Chiu T.H., Wu F.Y. Prenatal smoking exposure and neonatal DNA damage in relation to birth outcomes. Pediatr. Res. 2008, 64:131-134.
12. Madamanchi N.R., Vendrov A., Runge M. Oxidative stress and vascular disease. Arterioscler. Thromb. Vasc. Biol. 2005, 25:29-38.
13. Stocker R., Keaney J.F. New insights on oxidative stress in the artery wall. J. Thromb. Haemost. 2005, 3:1825-1834.
14. Botto N., Masetti S., Petrozzi L., Vassalle C., Manfredi S., Biagini A., Andreassi M.G. Elevated levels of oxidative DNA damage in patients with coronary artery disease. Coron. Artery Dis. 2002, 13:269-274.
15. Demirbag R., Yilmaz R., Gur M., Kocyigit A., Celik H., Guzel S., Selek S. Lymphocyte DNA damage in patients with acute coronary syndrome and its relationship with severity of acute coronary syndrome. Mutat. Res. 2005, 578:298-307.
16. Demirbag R., Yilmaz R., Kocyigit A., Guzel S. Effect of coronary angiography on oxidative DNA damage observed in circulating lymphocytes. Angiology 2007, 58:141-147.
17. Mesbah-Namin S.A., Nemati A., Tiraihi T. Evaluation of DNA damage in leukocytes of G6PD deficient Iranian newborns using comet assay. Mutat. Res. 2004, 568:179-185.
18. Ceylan E., Kocyigit A., Gencer M., Aksoy N., Selek S. Increased DNA damage in patients with chronic obstructive pulmonary disease who had once smoked or been exposed to biomass. Respir. Med. 2006, 100:1270-1276.
19. Stap J., Krawczyk P.M., Van Oven C.H., Barendsen G.W., Essers J., Kanaar R., Aten J.A. Induction of linear tracks of DNA double-strand breaks by alpha-particle irradiation of cells. Nat. Methods 2008, 5:261-266.
20. Arbillaga L., Azqueta A., Ezpeleta O., Lopez de Cerain A. Oxidative DNA damage induced by Ochratoxin A in the HK-2 human kidney cell line: evidence of the relationship with cytotoxicity. Mutagenesis 2007, 22:35-42.
21. Chye S.M., Hseu Y.C., Liang S.H., Chen C.H., Chen S.C. Single strand DNA breaks in human lymphocytes exposed to paraphenylenediamine and its derivatives. Bull. Environ. Contam. Toxicol. 2008, 80:58-62.
22. Li L., Jiang L., Geng C., Cao J., Zhong L. The role of oxidative stress in acrolein-induced DNA damage in HepG2 cells. Free Radic. Res. 2008, 42:354-361.
23. Pavlova E.L., Marinov R.A., Savov V.M., Pilossoff V.B. Oxidative stress in children undergoing surgical corrections of congenital heart malformations. Pediatr. Oncall 2009, 6. Article number 49.
24. Ercan S., Çakmak A., Kösecik M., Erel O. The oxidative state of children with cyanotic and acyanotic congenital heart disease. Anadolu Kardiyol. Derg. 2009, 9:486-490.
25. Huang Y., Hickey R.P., Yeh J.L., Liu D., Dadak A., Young L.H., Johnson R.S., Giordano F.J. Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart. FASEB J. 2004, 18:1138-1140.
26. Snider B.J., Gottron F.J., Choi D.W. Apoptosis and necrosis in cerebrovascular disease. Ann. N. Y. Acad. Sci. 1999, 893:243-253.
27. Guo K., Searfoss G., Krolikowski D., Pagnoni M., Franks C., Clark K., Yu K.T., Jaye M., Ivashchenko Y. Hypoxia induces the expression of the pro-apoptotic gene. BNIP3 Cell Death Differ. 2001, 8:367-376.
28. Qing M., Görlach A., Schumacher K., Wöltje M., Vazquez-Jimenez J.F., Hess J., Seghaye M.C. The hypoxia-inducible factor HIF-1 promotes intramyocardial expression of VEGF in infants with congenital cardiac defects. Basic Res. Cardiol. 2007, 102:368.
29. Ferreiro C.R., Chagas A.C.P., Carvalho M.H.C., Dantas A.P., Jatene M.B., de-Souza L.C.B., da-Luz P'sio.L. Influence of hypoxia on nitric oxide synthase activity and gene expression in children with congenital heart disease a novel pathophysiological adaptive mechanism. Circulation 2001, 103:2272-2276.
30. Roos W.P., Kaina B. DNA damage-induced cell death by apoptosis. Trends Mol. Med. 2006, 12:440-450.