A simplified approach to human islet quality assessment

Transplantation

Volumn 89, Issue 10, 2010, Pages 1178-1188

  Hanson, Matthew S ^a   Park, Elisa E ^a   Sears, Mallory L ^a   Greenwood, Krista K ^a   Danobeitia, Juan Sebastian ^a   Hullett, Debra A ^a   Fernandez, Luis A ^a  

^a University of Wisconsin Health   (United States)

Author keywords

Diabetes; Flow cytometry; Islet; Mitochondria; Transplantation

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL COUNT; CELL LOSS; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; QUALITY CONTROL; STREPTOZOCIN DIABETES; TREATMENT RESPONSE;

ANIMALS; BIOLOGICAL MARKERS; CELL CULTURE TECHNIQUES; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; ELECTRON TRANSPORT; FLOW CYTOMETRY; GLUCOSE; GRAFT SURVIVAL; HUMANS; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED NOD; MITOCHONDRIA; TREATMENT OUTCOME;

EID: 77952841443     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3181d54bce     Document Type: Article

References (31)

1. Collaborative Islet Transplant Registry. Sixth Annual Report. Rock-ville, MD: Collaborative Islet Transplant Registry, 2009: 240.
2. Abdelli S, Ansite J, Roduit R, et al. Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure. Diabetes 2004; 53: 2815.
3. Schwarznau A, Hanson MS, Sperger JM, et al. IL-1beta receptor blockade protects islets against pro-inflammatory cytokine induced necrosis and apoptosis. J Cell Physiol 2009; 220: 341.
4. Armann B, Hanson MS, Hatch E, et al. Quantification of basal and stimulated ROS levels as predictors of islet potency and function. Am J Transplant 2007; 7: 38.
5. Thomas DA, Stauffer C, Zhao K, et al. Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function. J Am Soc Nephrol 2007; 18: 213.
6. van Loo G, Saelens X, van Gurp M, et al. The role of mitochondrial factors in apoptosis: A Russian roulette with more than one bullet. Cell Death Differ 2002; 9: 1031.
7. Fariss MW, Chan CB, Patel M, et al. Role of mitochondria in toxic oxidative stress. Mol Interv 2005; 5: 94.
8. Ricordi C, Lacy PE, Finke EH, et al. Automated method for isolation of human pancreatic islets. Diabetes 1988; 37: 413.
9. Hohmeier HE, Mulder H, Chen G, et al. Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and-independent glucose-stimulated insulin secretion. Diabetes 2000; 49: 424.
10. Gellerich FN, Kunz W. Cause and consequences of dynamic compart-mentation of adenine nucleotides in the mitochondrial intermem-brane space in respect to exchange of energy rich phosphates between cytosol and mitochondria. Biomed Biochim Acta 1987; 46: S545.
11. Noack H, Kunz WS, Augustin W. Evaluation of a procedure for the simultaneous determination of oxidized and reduced pyridine nucleotides and adenylates in organic phenol extracts from mitochondria. Anal Biochem 1992; 202: 162.
12. Linden A. Measuring diagnostic and predictive accuracy in disease management: An introduction to receiver operating characteristic (ROC) analysis. J Eval ClinPract 2006; 12: 132.
13. Ricordi C, Gray DW, Hering BJ, et al. Islet isolation assessment in man and large animals. Acta Diabetol Lat 1990; 27: 185.
14. Eckhard M, Brandhorst D, Winter D, et al. The role of current product release criteria for identification of human islet preparations suitable for clinical transplantation. Transplant Proc 2004; 36: 1528.
15. Barnett MJ, McGhee-Wilson D, Shapiro AM, et al. Variation in human islet viability based on different membrane integrity stains. Cell Transplant 2004; 13: 481.
16. Campbell PM, Senior PA, Salam A, et al. High risk of sensitization after failed islet transplantation. Am J Transplant 2007; 7: 2311.
17. Ichii H, Inverardi L, Pileggi A, et al. A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations. Am J Transplant 2005; 5: 1635.
18. Street CN, Lakey JR, Shapiro AM, et al. Islet graft assessment in the Edmonton Protocol: Implications for predicting long-term clinical outcome. Diabetes 2004; 53: 3107.
19. Papas KK, Colton CK, Nelson RA, et al. Human islet oxygen consumption rate and DNA measurements predict diabetes reversal in nude mice. Am J Transplant 2007; 7: 707.
20. Fraker C, Timmins MR, Guarino RD, et al. The use of the BD oxygen biosensor system toassess isolated human islets of Langerhans: Oxygen consumption as a potential measure of islet potency. Cell Transplant 2006; 15: 745.
21. Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 1998; 60: 619.
22. Duchen MR. Roles of mitochondria in health and disease. Diabetes 2004; 53(suppl 1): S96.
23. Lakey JR, Warnock GL, Rajotte RV,etal. Variablesinorgan donors that affect the recovery of human islets of Langerhans. Transplantation 1996; 61: 1047.
24. Nano R, Clissi B, Melzi R, et al. Islet isolation for allotransplantation: Variables associated with successful islet yield and graft function. Dia-betologia 2005; 48: 906.
25. Sweet IR, Gilbert M,JensenR, et al. Glucose stimulationofcytochrome C reduction and oxygen consumption as assessment of human islet quality. Transplantation 2005; 80: 1003.
26. Matsui Y, Kitade H, Kamiya T, et al. Adenylate energy charge of rat and human cultured hepatocytes. In Vitro Cell Dev Biol Anim 1994; 30A: 609.
27. Leist M, Single B, Castoldi AF, et al. Intracellular adenosine triphos-phate (ATP) concentration: Aswitchin the decision between apoptosis and necrosis. J Exp Med 1997; 185: 1481.
28. Bradbury DA, Simmons TD, Slater KJ, Crouch SP. Measurementof the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis. J Immunol Methods 2000; 240: 79.
29. Li G, Segu VB, Rabaglia ME, et al. Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis. Endocrinology 1998; 139: 3752.
30. Pipeleers D, Keymeulen B, Chatenoud L, et al. A view on beta cell transplantation in diabetes. Ann N Y Acad Sci 2002; 958: 69.
31. Jayaraman S. A novel method for the detection of viable human pancreatic beta cells by flow cytometry using fluorophores that selectively detect labile zinc, mitochondrial membrane potential and protein thi-ols. Cytometry A 2008; 73: 615.