Effect of geranylgeranylaceton on cellular damage induced by proteasome inhibition in cultured spinal neurons

Journal of Neuroscience Research

Volumn 69, Issue 3, 2002, Pages 373-381

  Kikuchi, Seiji ^a   Shinpo, Kazuyoshi ^a   Takeuchi, Masayoshi ^b   Tsuji, Sachiko ^a   Yabe, Ichiro ^a   Niino, Masaaki ^a   Tashiro, Kunio ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKURIKU UNIVERSITY   (Japan)

Author keywords

ALS; Apoptosis; Glycoxidation; Motor neuron; Ubiquitin

Indexed keywords

ANTIULCER AGENT; EPOXOMICIN; GLUTAMINE; HEAT SHOCK PROTEIN 70; LACTACYSTIN; PROTEASOME; PROTEASOME INHIBITOR; TEPRENONE; THIOREDOXIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DEGENERATIVE DISEASE; DOSE TIME EFFECT RELATION; ENZYME INHIBITION; ENZYME MECHANISM; GLUTATHIONE METABOLISM; GRANULAR CELL; MOTOR NEURON DISEASE; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PROCESSING; RAT; SHORT SURVEY; SPINAL CORD NERVE CELL;

ACETYLCYSTEINE; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HSP70 HEAT-SHOCK PROTEINS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MITOCHONDRIA; MULTIENZYME COMPLEXES; NEURONS; NEUROPROTECTIVE AGENTS; OLIGOPEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SPINAL CORD; THIOREDOXIN; TIME FACTORS;

EID: 0036681984     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10298     Document Type: Short Survey

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