Effects of Different Intensity Resistance Exercise Programs on Bone Turnover Markers, Osteoprotegerin and Receptor Activator of Nuclear Factor Kappa? Ligand in Post-Menopausal Women;Farklı şiddetteki direnç egzersiz programlarının postmenopozal kadınların kemik turn-over markerleri, osteoprotegerin ve nükleer faktör kappa B reseptör aktivatör ligandı üzerine etkileri

Turkiye Klinikleri Journal of Medical Sciences

Volumn 30, Issue 1, 2010, Pages 123-134

  Karaarslan, Serkan ^a   Büyükyazi, Gürbüz ^a   Taneli, Fatma ^a   Ulmans, Cevval ^a   Tikiz, Canan ^a   Gümüşer, Gül ^a   Şahan, Pinar ^a  

^a CELAL BAYAR UNIVERSITY   (Turkey)

Author keywords

Osteoporosis; Osteoprotegerin; Postmenopausal; RANK ligand

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; CARBOXY TERMINAL TELOPEPTIDE; OSTEOCALCIN; OSTEOPROTEGERIN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

ADULT; ARTICLE; BONE DENSITY; BONE TURNOVER; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME BLOOD LEVEL; EXERCISE INTENSITY; FEMALE; HUMAN; HUMAN EXPERIMENT; MUSCLE STRENGTH; NORMAL HUMAN; OSSIFICATION; OSTEOLYSIS; POSTMENOPAUSE; PREDICTION; PROTEIN BLOOD LEVEL; RESISTANCE TRAINING;

EID: 77952797017     PISSN: 13000292     EISSN: None     Source Type: Journal    
DOI: 10.5336/medsci.2008-8721     Document Type: Article

References (66)

1. Nelson ME, Fiatarone MA, Morganti CM, Trice I, Greenberg RA, Evans WJ. Effects of high-intensity strength training on multiple risk factors for osteoporotic fractures. A randomized controlled trial. JAMA 1994;272(24):1909-14.
2. Pruitt LA, Jackson RD, Bartels RL, Lehnhard HJ. Weight-training effects on bone mineral density in early postmenopausal women. J Bone Miner Res 1992;7(2):179-85.
3. Menkes A, Mazel S, Redmond RA, Koffler K, Libanati CR, Gundberg CM, et al. Strength training increases regional bone mineral density and bone remodeling in middle-aged and older men. J Appl Physiol 1993;74(5):2478-84.
4. Pruitt LA, Taaffe DR, Marcus R. Effects of a one-year high-intensity versus low-intensity resistance training program on bone mineral density in older women. J Bone Miner Res 1995;10(11):1788-95.
5. Ivaska KK, Hentunen TA, Vääräniemi J, Ylipahkala H, Pettersson K, Väänänen HK. Release of intact and fragmented osteocalcin molecules from bone matrix during bone resorption in vitro. J Biol Chem 2004;279(18):18361-9.
6. Fedde KN, Lane CC, Whyte MP. Alkaline phosphatase is an ectoenzyme that acts on micromolar concentrations of natural substrates at physiologic pH in human osteosarcoma (SAOS-2) cells. Arch Biochem Biophys 1988;264(2):400-9.
7. Ebeling PR, Peterson JM, Riggs BL. Utility of type I procollagen propeptide assays for assessing abnormalities in metabolic bone diseases. J Bone Miner Res 1992;7(11):1243-50.
8. Eriksen EF, Charles P, Melsen F, Mosekilde L, Risteli L, Risteli J. Serum markers of type I collagen formation and degradation in metabolic bone disease: correlation with bone histomorphometry. J Bone Miner Res 1993;8(2):127-32.
9. Kandemir N. [Osteocalcine, a new index for bone metabolism]. Turkiye Klinikleri J Med Sci 1991;11(3):194-6.
10. Ay A, Yurtkuran M. [Serum parathormone levels in postmenopausal healthy and osteoporotic women]. Turkiye Klinikleri J PM & R 2003;3(1):15-8.
11. Acar B, Şentürk T, Bilgehan Y. [Paget's disease of the bone in an asymptomatic case: differential diagnosis]. Turkiye Klinikleri J Med Sci 2008;28(3):415-8.
12. Hatori M, Hasegawa A, Adachi H, Shinozaki A, Hayashi R, Okano H, et al. The effects of walking at the anaerobic threshold level on vertebral bone loss in postmenopausal women. Calcif Tissue Int 1993;52(6):411-4.
13. Milliken LA, Going SB, Houtkooper LB, Flint-Wagner HG, Figueroa A, Metcalfe LL, et al. Effects of exercise training on bone remodeling, insulin-like growth factors, and bone mineral density in postmenopausal women with and without hormone replacement therapy. Calcif Tissue Int 2003;72(4):478-84.
14. Etherington J, Keeling J, Bramley R, Swaminathan R, McCurdie I, Spector TD. The effects of 10 weeks military training on heel ultrasound and bone turnover. Calcif Tissue Int 1999;64(5):389-93.
15. Chapurlat RD, Garnero P, Bréart G, Meunier PJ, Delmas PD. Serum type I collagen breakdown product (serum CTX) predicts hip fracture risk in elderly women: the EPIDOS study. Bone 2000;27(2):283-6.
16. Herrmann M, Herrmann W. The assessment of bone metabolism in female elite endurance athletes by biochemical bone markers. Clin Chem Lab Med 2004;42(12):1384-9.
17. Khosla S. Minireview: the OPG/RANKL/RANK system. Endocrinology 2001;142(12):5050-5.
18. Chambers TJ. Regulation of the differentiation and function of osteoclasts. J Pathol 2000;192(1):4-13.
19. Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki S, et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci U S A 1998;95(7):3597-602.
20. Takahashi N, Udagawa N, Suda T. A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function. Biochem Biophys Res Commun 1999;256(3):449-55.
21. Schoppet M, Preissner KT, Hofbauer LC. RANK ligand and osteoprotegerin: paracrine regulators of bone metabolism and vascular function. Arterioscler Thromb Vasc Biol 2002;22(4):549-53.
22. Yano K, Tsuda E, Washida N, Kobayashi F, Goto M, Harada A, et al. Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: increased serum concentrations in postmenopausal women with osteoporosis. J Bone Miner Res 1999 14(4):518-27.
23. Fraher LJ, Watson PH, Kisiel M, Natale BV, Hodsman AB. Measurement of circulating osteoprotegerin (OPG) in human sera: inhibition of circulating OPG in osteoporotic patients treated with hPTH (1-34). J Bone Miner Res 2000;15(Suppl 1):S441.
24. Bekker PJ, Holloway D, Nakanishi A, Arrighi M, Leese PT, Dunstan CR. The effect of a single dose of osteoprotegerin in postmenopausal women. J Bone Miner Res 2001;16(2):348-60.
25. Khosla S, Arrighi HM, Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Dunstan C, et al. Correlates of osteoprotegerin levels in women and men. Osteoporos Int 2002;13(5):394-9.
26. Browner WS, Lui LY, Cummings SR. Associations of serum osteoprotegerin levels with diabetes, stroke, bone density, fractures, and mortality in elderly women. J Clin Endocrinol Metab 2001;86(2):631-7.
27. Indridason OS, Franzson L, Sigurdsson G. Serum osteoprotegerin and its relationship with bone mineral density and markers of bone turnover. Osteoporos Int 2005;16(4):417-23.
28. Kudlacek S, Schneider B, Woloszczuk W, Pietschmann P, Willvonseder R; Austrian Study Group on Normative Values of Bone Metabolism. Serum levels of osteoprotegerin increase with age in a healthy adult population. Bone 2003;32(6):681-6.
29. Kim JG, Kim JH, Lee DO, Kim H, Kim JY, Suh CS, et al. Changes in the serum levels of osteoprotegerin and soluble receptor activator for nuclear factor kappaB ligand after estrogenprogestogen therapy and their relationships with changes in bone mass in postmenopausal women. Menopause 2008;15(2):357-62.
30. Liu JM, Zhao HY, Ning G, Zhao YJ, Chen Y, Zhang Zh, et al. Relationships between the changes of serum levels of OPG and RANKL with age, menopause, bone biochemical markers and bone mineral density in Chinese women aged 20-75. Calcif Tissue Int 2005;76(1):1-6.
31. Hinton PS, Rector RS, Thomas TR. Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women. Metabolism 2006;55(12):1616-8.
32. Kanis JA. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. WHO Study Group. Osteoporos Int 1994;4(6):368-81.
33. Walker SN, Sechrist KR, Pender NJ. The HealthPromoting Lifestyle Profile: development and psychometric characteristics. Nurs Res 1987;36(2):76-81.
34. American College of Sports Medicine Position Stand. The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc 1998;30(6):975-91.
35. Chamay A, Tschantz P. Mechanical influences in bone remodeling. Experimental research on Wolff's law. J Biomech 1972;5(2):173-80.
36. Karlsson MK, Johnell O, Obrant KJ. Bone mineral density in weight lifters. Calcif Tissue Int 1993;52(3):212-5.
37. Hamdy RC, Anderson JS, Whalen KE, Harvill LM. Regional differences in bone density of young men involved in different exercises. Med Sci Sports Exerc 1994;26(7):884-8.
38. Heinonen A, Oja P, Kannus P, Sievänen H, Mänttäri A, Vuori I. Bone mineral density of female athletes in different sports. Bone Miner 1993;23(1):1-14.
39. Fehling PC, Alekel L, Clasey J, Rector A, Stillman RJ. A comparison of bone mineral densities among female athletes in impact loading and active loading sports. Bone 1995;17(3):205-10.
40. Taaffe DR, Marcus R. Regional and total body bone mineral density in elite collegiate male swimmers. J Sports Med Phys Fitness 1999;39(2):154-9.
41. Vincent KR, Braith RW. Resistance exercise and bone turnover in elderly men and women. Med Sci Sports Exerc 2002;34(1):17-23.
42. Nichols JF, Nelson KP, Peterson KK, Sartoris DJ. Bone mineral density responses to high-intensity strength training in active older women. JAPA 1995;3(1):26-38.
43. Wallace BA, Cumming RG. Systematic review of randomized trials of the effect of exercise on bone mass in preand postmenopausal women. Calcif Tissue Int 2000;67(1):10-8.
44. Bérard A, Bravo G, Gauthier P. Meta-analysis of the effectiveness of physical activity for the prevention of bone loss in postmenopausal women. Osteoporos Int 1997;7(4):331-7.
45. Colletti LA, Edwards J, Gordon L, Shary J, Bell NH. The effects of muscle-building exercise on bone mineral density of the radius, spine, and hip in young men. Calcif Tissue Int 1989;45(1):12-4.
46. Conroy BP, Kraemer WJ, Maresh CM, Fleck SJ, Stone MH, Fry AC, et al. Bone mineral density in elite junior Olympic weightlifters. Med Sci Sports Exerc 1993;25(10):1103-9.
47. Kerr D, Morton A, Dick I, Prince R. Exercise effects on bone mass in postmenopausal women are site-specific and load-dependent. J Bone Miner Res 1996;11(2):218-25.
48. Tsuzuku S, Ikegami Y, Yabe K. Effects of high-intensity resistance training on bone mineral density in young male powerlifters. Calcif Tissue Int 1998;63(4):283-6.
49. Granhed H, Jonson R, Hansson T. The loads on the lumbar spine during extreme weight lifting. Spine (Phila Pa 1976) 1987;12(2):146-9.
50. Davey RC, Fongchotip P, Cochrane T, Heffron M. Bone mineral response to exercise in postmenopausal women. Br J Therapy Rehabil 2002;9(7):260-5.
51. Taaffe DR, Pruitt L, Pyka G, Guido D, Marcus R. Comparative effects of high and low-intensity resistance training on thigh muscle strength, fiber area, and tissue composition in elderly women. Clin Physiol 1996;16(4):381-92.
52. Brown AB, McCartney N, Sale DG. Positive adaptations to weight-lifting training in the elderly. J Appl Physiol 1990;69(5):1725-33.
53. Frontera WR, Meredith CN, O'Reilly KP, Knuttgen HG, Evans WJ. Strength conditioning in older men: skeletal muscle hypertrophy and improved function. J Appl Physiol 1988;64(3):1038-44.
54. Hagberg JM, Graves JE, Limacher M, Woods DR, Leggett SH, Cononie C, et al. Cardiovascular responses of 70 to 79-yr-old men and women to exercise training. J Appl Physiol 1989;66(6):2589-94.
55. Charhon SA, Delmas PD, Malaval L, Chavassieux PM, Arlot M, Chapuy MC, et al. Serum bone Gla-protein in renal osteodystrophy: comparison with bone histomorphometry. J Clin Endocrinol Metab 1986;63(4):892-7.
56. Brooke-Wavell K, Jones PR, Hardman AE, Yamada Y. Commencing, continuing and stopping brisk walking: effects on bone mineral density, quantitative ultrasound of bone and markers of bone metabolism in postmenopausal women. Osteoporos Int 2001;12(7):581-7.
57. Rudberg A, Magnusson P, Larsson L, Joborn H. Serum isoforms of bone alkaline phosphatase increase during physical exercise in women. Calcif Tissue Int 2000;66(5):342-7.
58. Fujimura R, Ashizawa N, Watanabe M, Mukai N, Amagai H, Fukubayashi T, et al. Effect of resistance exercise training on bone formation and resorption in young male subjects assessed by biomarkers of bone metabolism. J Bone Miner Res 1997;12(4):656-62.
59. Menkes A, Mazel S, Redmond RA, Koffler K, Libanati CR, Gundberg CM, et al. Strength training increases regional bone mineral density and bone remodeling in middle-aged and older men. J Appl Physiol 1993;74(5):2478-84.
60. Fahrleitner A, Prenner G, Leb G, Tscheliessnigg KH, Piswanger-Sölkner C, Obermayer-Pietsch B, et al. Serum osteoprotegerin is a major determinant of bone density development and prevalent vertebral fracture status following cardiac transplantation. Bone 2003;32(1):96-106.
61. Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Spelsberg TC, Riggs BL. Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology 1999;140(9):4367-70.
62. Doumouchtsis KK, Kostakis AI, Doumouchtsis SK, Tziamalis MP, Stathakis CP, Diamanti-Kandarakis E, et al. Associations between osteoprotegerin and femoral neck BMD in hemodialysis patients. J Bone Miner Metab 2008;26(1):66-72.
63. Franchimont N, Reenaers C, Lambert C, Belaiche J, Bours V, Malaise M, et al. Increased expression of receptor activator of NF-kappaB ligand (RANKL), its receptor RANK and its decoy receptor osteoprotegerin in the colon of Crohn's disease patients. Clin Exp Immunol 2004;138(3):491-8.
64. Kim HR, Lee SH, Kim HY. Elevated serum levels of soluble receptor activator of nuclear factorskappaB ligand (sRANKL) and reduced bone mineral density in patients with ankylosing spondylitis (AS). Rheumatology (Oxford) 2006;45(10):1197-200.
65. Uemura H, Yasui T, Miyatani Y, Yamada M, Hiyoshi M, Arisawa K, et al. Circulating profiles of osteoprotegerin and soluble receptor activator of nuclear factor kappaB ligand in post-menopausal women. J Endocrinol Invest 2008;31(2):163-8.
66. Oh KW, Rhee EJ, Lee WY, Kim SW, Baek KH, Kang MI, et al. Circulating osteoprotegerin and receptor activator of NF-kappaB ligand system are associated with bone metabolism in middle-aged males. Clin Endocrinol (Oxf) 2005;62(1):92-8.