Effects of exercise training on bone remodeling, insulin-like growth factors, and bone mineral density in postmenopausal women with and without hormone replacement therapy

Calcified Tissue International

Volumn 72, Issue 4, 2003, Pages 478-484

  Milliken, L A ^a   Going, S B ^b   Houtkooper, L B ^b   Flint Wagner, H G ^c   Figueroa, A ^c   Metcalfe, L L ^c   Blew, R M ^c   Sharp, S C ^c   Lohman, T G ^c  

^a UNIVERSITY OF MASSACHUSETTS BOSTON   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Bone remodeling; Exercise training; Hormone therapy

Indexed keywords

ESTROGEN; PROGESTERONE; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; TESTOSTERONE;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; BONE DENSITY; BONE GROWTH; BONE MASS; BONE MINERAL; BONE REMODELING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; EXERCISE; FEMALE; HORMONE SUBSTITUTION; HUMAN; MAJOR CLINICAL STUDY; OSTEOLYSIS; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUBSTITUTION THERAPY; TRAINING; WEIGHT BEARING;

ADULT; AGED; BONE DENSITY; BONE REMODELING; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; EXERCISE THERAPY; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; MIDDLE AGED; OSTEOPOROSIS; OSTEOPOROSIS, POSTMENOPAUSAL; PHYSICAL FITNESS; PROGESTERONE; SOMATOMEDINS; TESTOSTERONE; TREATMENT OUTCOME;

EID: 0042267854     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-001-1128-5     Document Type: Article

References (19)

1. Layne JE, Nelson M (1999) The effects of progressive resistance training on bone density: a review. Med Sci Sports Exerc 31:25-30
2. Wolff I, van Croonenborg JJ, Kemper HCG, Kostense PJ, Twisk JWR (1999) The effect of exercise training programs on bone mass: a meta-analysis of published controlled trials in pre- and post-menopausal women. Osteoporos Int 9:1-12
3. Smith EL, Gilligan C (1996) Dose-response relationship between physical loading and mechanical competence of bone. Bone 18:S45-S50
4. Isaksson O, Lindahl A, Nilsson A, Isgaard J (1987) Mechanism of the stimulatory effect of growth hormone on longitudinal bone growth. Endocr Rev 8:426-438
5. Rosen CJ, Donahue LR, Hunter SJ (1994) Insulin-like growth factors and bone: the osteoporosis connection. Proc Soc Exp Biol Med 206:83-102
6. Bennet AE, Wahner HW, Riggs BL, Hintz R (1984) Insulin-like growth factors I and II: aging and bone density in women. J Clin Endocrinol Metab 59:701-704
7. Nicolas V, Prewett A, Bettica P, Mohan S, Finkelman RD, Baylink DJ, Farley JR (1994) Age-related decreases in insulin-like growth factor-I and transforming growth factor beta in femoral cortical bone from both men and women: implications for bone loss with aging. J Clin Endocrinol Metab 78:1011-1016
8. Kohrt WM, Snead DB, Slatopolsky E, Birge Jr SJ (1995) Additive effects of weight-bearing exercise and estrogen on bone mineral density in older women. J Bone Miner Res 10:1303-1311
9. Prince RL, Smith M, Dick IM, Price RI, Webb PG, Henderson NK, Harris MM (1991) Prevention of postmenopausal osteoporosis: a comparative study of exercise, calcium supplementation, and hormone-replacement therapy. N Engl J Med 325:1189-1195
10. Prestwood KM, Pilbeam CC, Burleson JA, Woodiel FN, Delmas PD, Deftos LJ, Raisz LG (1994) The short-term effects of conjugated estrogen on bone turnover in older women. J Clin Endocrinol Metab 79:366-371
11. Raisz LG, Wiita B, Artis A, Bowen A, Schwartz S, Trahiotis M, Shoukri K, Smith J (1996) Comparison of the effects of estrogen alone and estrogen plus androgen on biochemical markers of bone formation and resorption in postmenopausal women. J Clin Endocrinol Metab 81:37-43
12. Dalsky GP, Stocke KS, Elsani AA, Statopolsky E, Waldon CL, Binge SJ (1988) Weight-bearing exercise training and lumbar bone mineral content on postmenopausal women. Ann Int Med 108:824-828
13. Hatori M, Hasegawa A, Adachi H, Shinozaki A, Hayashi H, Okano H, Mizunuma H, Murata K (1993) The effects of walking at the anaerobic threshold level on vertebral bone loss in postmenopausal women. Calcif Tissue Int 52:411-414
14. Nelson ME, Fiatarone MA, Morganti CM, Trice I, Greenberg RA, Evans WJ (1994) Effects of high-intensity strength training on multiple risk factors for osteoporotic fractures: a controlled clinical trial. JAMA 272:1909-1914
15. Turner CH (1991) Homeostatic control of bone structure: an application of feedback theory. Bone 12:203-217
16. Massa G, Igout A, Rombauts L, Frankenne F, Vanderschueren-Lodeweychx M (1993) Effect of oestrogen status on serum levels of growth hormone-binding protein and insulin-like growth factor-1 in non-pregnant and pregnant women. Clin Endocrinol 39:569-575
17. Weissberger AJ, Ho KY, Lazarus L (1991) Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24 hour growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women. J Clin Endocrinol Metab 72:374-381
18. Kohrt WM, Ehsani AA, Birge Jr SJ (1997) Effects of exercise involving predominantly either joint-reaction or ground-reaction forces on bone mineral density in older women. J Bone Miner Res 12:1253-1261
19. Lanyon LE (1996) Using functional loading to influence bone mass and architecture: objectives, mechanisms, and relationship with estrogen of the mechanically adaptive process in bone. Bone 18:S37-S43