Acetaminophen-induced cytotoxicity on human normal liver L-02 cells and the protection of antioxidants

Toxicology Mechanisms and Methods

Volumn 20, Issue 5, 2010, Pages 273-278

  Liang, Qingning ^a,b   Sheng, Yuchen ^b   Ji, Lili ^a,c   Min, Yang ^b   Xia, Yuye ^b   Wang, Zhengtao ^a,c  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY   (China)

^c Shanghai R and D Centre for Standardization of Chinese Medicines   (China)

Author keywords

Apoptosis; CYP2E1; GSH; Hepatocytes; Oxidative stress injury

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; BUTHIONINE SULFOXIMINE; CASPASE 3; CYTOCHROME P450 2E1; GLUTATHIONE; PARACETAMOL;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER TOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; WESTERN BLOTTING;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANTIOXIDANTS; BUTHIONINE SULFOXIMINE; CELL LINE; CYTOCHROME P-450 CYP2E1; HUMANS; LIVER; OXIDATIVE STRESS;

EID: 77952790315     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2010.482963     Document Type: Article

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