Differential response of heat-shock-induced p38 MAPK and JNK activity in PC12 mutant and PC12 parental cells for differentiation and apoptosis

Acta Medica Okayama

Volumn 64, Issue 1, 2010, Pages 55-62

  Murai, Hiroyasu ^a   Hiragami, Fukumi ^a   Kawamura, Kenji ^a   Motoda, Hirotoshi ^a   Koike, Yoshihisa ^b   Inoue, Shigeki ^a   Kumagishi, Kanae ^c   Ohtsuka, Aiji ^c   Kano, Yoshio ^a  

^a KIBI INTERNATIONAL UNIVERSITY   (Japan)

^b PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

Heat shock; JNK; Neurite outgrowth; p38 MAP kinase; PC12 mutant cells

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN; HEAT SHOCK RESPONSE; METABOLISM; NERVE CELL; NEURITE; PHYSIOLOGICAL STRESS; PHYSIOLOGY; RAT; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; HEAT-SHOCK RESPONSE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NEURITES; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PC12 CELLS; RATS; STRESS, PHYSIOLOGICAL;

EID: 77952765908     PISSN: 0386300X     EISSN: 0386300X     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Mielke K and Herdegen T: JNK and p38 stresskinases-degenerative effectors of signal-transduction-cascades in the nervous system. Prog Neurobiol (2000) 61: 45-60.
2. Martin SJ, Newmeyer DD, Mathias S, Farschon DM, Wang HG, Reed JC, Kolesnick RN and Green DR: Cell-free reconstitution of Fas-, UV radiation-and ceramide-induced apoptosis. EMBO J (1995) 14: 5191-5200.
3. Rosette C and Karin M: Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science (1996) 274: 1194-1197.
4. Morooka T and Nishida E: Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells. J Biol Chem (1998) 273: 24285-24288.
5. Kano Y, Nohno T, Shimada K, Nakagiri S, Hiragami F, Kawamura K, Motoda H, Numata K, Murai H, Koike Y, Inoue S and Miyamoto K: Osmotic shock-induced neurite extension via activation of p38 mitogen-activated protein kinase and CREB. Brain Res (2007) 1154: 1-7.
6. Kano Y, Nohno T, Takahashi R, Hasegawa T, Hiragami F, Kawamura K, Motoda H and Sugiyama T: cAMP and calcium ion-ophore induce outgrowth of neuronal processes in PC12 mutant cells in which nerve growth factor-induced outgrowth of neuronal processes is impaired. Neurosci Lett (2001) 303: 21-24.
7. Kano Y, Nakagiri S, Nohno T, Hiragami F, Kawamura K, Kadota M, Numata K, Koike T and Furuta T: Heat shock induces neurite out-growth in PC12m3 cells via the p38 mitogen-activated protein kinase pathway. Brain Res (2004) 1026: 302-306.
8. Muniyappa H and Das KC: Activation of c-jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: A MLK-3-MKK7-dependent mechanisms. Cellular Signal (2008)20: 675-683.
9. 2+ influx. J Biol Chem (1999) 274: 29666-29671.
10. Xia Z, Dickens M, Raingeaud J, Davis RJ and Greenberg ME: Opposing effects of ERK and JNL-p38 MAP kinases on apoptosis. Science (1995) 270: 1326-1331.
11. di Mari JF, Davis R and Safirstein RL: MAPK activation determines renal epithelial cell survival during oxidative injury. Am J Physiol (1999) 277: F195-203.
12. Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, Jones SN, Flavell RA and Davis RJ: Requirement of JNK for stress-induced activation of the cytochrom c-mediated death pathway. Science (2000) 288: 870-874.
13. Nagata Y and Todokoro K: Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis. Blood (1999) 94: 853-863.
14. Chen YR, Wang X, Templeton D, Davis RJ and Tan TH: The role of c-jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem (1996) 271: 31929-31936.
15. Phang D, Joyce EM and Heikkila JJ: Heat shock-induced acquisition of thermotolerance at the levels of cell survival and translation in Xenopus A6 kidney epithelial cells. Biochem Cell Biol (1999) 77:141-151.
16. Mearow KM, Dodge ME, Rahimtula M and Yegappan C: Stress-mediated signaling in PC12 cells-the role of small heat shock protein, Hsp27, and Akt in protecting cells from heat stress and nerve growth factor withdrawal. J Neurochem (2002) 83: 452-462.
17. Mearow KM, Dodge ME, Rahimtula M and Yegappan C: Stress-mediated signaling in PC12 cells-the role of the small heat shock protein, Hsp27, and Akt in protecting cells from heat stress and nerve growth factor withdrawal. J Neurochem (2002) 83: 452-462.
18. Samali A and Cotter TG: Heat shock proteins increase resistance to apoptosis. Exp Cell Res (1996) 223: 163-170.
19. Lee JS, Lee JJ and Seo JS: HSP70 deficiency results in activation of c-Jun N-terminal kinase, extracellular signal-regulated kinase, and caspase-3 in hyperosmolarity-induced apoptosis. J Biol Chem (2005) 280: 6634-6641.
20. Park HS, Lee JS, Huh SH, Seo JS and Choi EJ: Hsp72 functions as a natural inhibitory protein of c-Jun N-terninal kinase. EMBO J (2001) 20: 446-456.