cAMP and calcium ionophore induce outgrowth of neuronal processes in PC12 mutant cells in which nerve growth factor-induced outgrowth of neuronal processes is impaired

Neuroscience Letters

Volumn 303, Issue 1, 2001, Pages 21-24

  Kano, Yoshio ^a   Nohno, Tsutomu ^b   Takahashi, Rei ^c   Hasegawa, Toru ^b   Hiragami, Fukumi ^a   Kawamura, Kenji ^a   Motoda, Hirotoshi ^c   Sugiyama, Taketoshi ^d  

^a KIBI INTERNATIONAL UNIVERSITY   (Japan)

^b KAWASAKI MEDICAL SCHOOL   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d Shiga Medical Center   (Japan)

Author keywords

A23187; Cydic adenosine monophosphate; Mitogen activated protein; PC12 mutant cells

Indexed keywords

CALCIMYCIN; CALCIUM IONOPHORE; CYCLIC AMP; HYALURONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL MUTANT; CONTROLLED STUDY; DENDRITE; ENZYME ACTIVITY; NERVE FIBER GROWTH; NONHUMAN; OSMOLARITY; PRIORITY JOURNAL; RAT;

ANIMALS; AXONS; CALCIMYCIN; CALCIUM-BINDING PROTEINS; CYCLIC AMP; DENDRITES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTOR; OSMOLAR CONCENTRATION; PC12 CELLS; RATS;

EID: 0035957869     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01676-7     Document Type: Article

References (19)

1. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH3T3 cells
2. JNKI: A protein kinase stimulated by UV light and Ha-ras that phosphorylates the c-jun activation domain
3. Induction of neurite outgrowth by MAP kinase in PC12 cells
4. An osmosensing signal transduction pathway in mammalian cells
5. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
6. Nerfilin I, a novel microbial metabolite inducing neurite outgrowth of PC12 cells
7. The trk proto-oncogene product: A signal transducing receptor for nerve growth factor
8. The stress-activated protein kinase subfamily of c-Jun kinases
9. Activation of protein kinase cascades by osmotic shock
10. Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active ras GTP complex in rat pheochromocytoma PC12 cells
11. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
12. Calcium influx induces neurite growth through a src-ras signaling cassette
13. Enhancement of neurite outgrowth in PC12h cells by a protease inhibitor
14. 2+ influx
15. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
16. Induction of neurite outgrowth in PC12 cells by γ -lactam-related compounds via Ras-MAP kinase signaling pathway independent mechanism
17. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
18. Differentiation of PC12 cells in response to a cAMP analog is accompanied by sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters
19. Ras and rap1: Two highly related small GTPases with distinct function