Controlled release of dexamethasone from subcutaneouslyimplanted biosensors in pigs: Localized anti-inflammatory benefit without systemic effects

Journal of Biomedical Materials Research - Part A

Volumn 94, Issue 1, 2010, Pages 280-287

  Ward, W Kenneth ^a,b   Hansen, Jillian C ^a   Massoud, Ryan G ^a   Engle, Julia M ^a   Takeno, Marc M ^c   Hauch, Kip D ^c  

^a LEGACY HEALTH SYSTEM   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c University of Washington   (United States)

Author keywords

Dexamethasone; Eosinophil; Foreign body response; Glucose sensor; Medical device

Indexed keywords

ANALYTES; ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY EFFECTS; COLLAGEN DEPOSITION; CONTROLLED RELEASE; DEXAMETHASONES; EOSINOPHIL; FOREIGN BODY RESPONSE; LARGE PARTS; MEDICAL DEVICES; RELEASE RATE; SIDE EFFECT;

BIOMEDICAL ENGINEERING; BIOSENSORS; BODY FLUIDS; COLLAGEN; ENZYME SENSORS; GLUCOSE; GLUCOSE SENSORS; MACROPHAGES;

DRUG PRODUCTS;

DEXAMETHASONE; HYDROCORTISONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOSENSOR; BLOOD SAMPLING; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG IMPLANT; EOSINOPHIL; EXPLANT; GRANULOCYTE; HISTOLOGY; HYDROCORTISONE BLOOD LEVEL; IMPLANT; MACROPHAGE; MALE; NONHUMAN; SINGLE BLIND PROCEDURE; SUBCUTANEOUS TISSUE; TREATMENT DURATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOSENSING TECHNIQUES; DEXAMETHASONE; GRANULOCYTES; HUMANS; HYDROCORTISONE; IMPLANTS, EXPERIMENTAL; MACROPHAGES; SUS SCROFA;

EID: 77952710571     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32651     Document Type: Article

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