Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia

Journal of Lipid Research

Volumn 51, Issue 6, 2010, Pages 1524-1534

  Sundaram, Meenakshi ^a   Zhong, Shumei ^a   Khalil, Maroun Bou ^a   Zhou, Hu ^b   Jiang, Zhenghui G ^b   Zhao, Yang ^c   Iqbal, Jahangir ^d   Hussain, M Mahmood ^a,b,c,d   Figeys, Daniel ^a   Wang, Yuwei ^a   Yao, Zemin ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MAZANKOWSKI ALBERTA HEART INSTITUTE   (Canada)

^d SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

Apolipoprotein C III; Lumenal lipid droplets; Triacylglycerol; VLDL assembly

Indexed keywords

ALANINE; APOLIPOPROTEIN C3; BREFELDIN A; FAT DROPLET; HISTONE H3; INTERMEDIATE DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; SERINE; THREONINE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; HYPOTRIGLYCERIDEMIA; LIPOGENESIS; METABOLIC DISORDER; MICROSOME; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; WILD TYPE;

ALANINE; APOLIPOPROTEINS C; BREFELDIN A; CARRIER PROTEINS; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM DISORDERS; LIPOPROTEINS, IDL; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; MICROSOMES; MODELS, MOLECULAR; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; THREONINE; TRIGLYCERIDES;

EID: 77952709284     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M005108     Document Type: Article

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