IL-4Rα-responsive smooth muscle cells increase intestinal hypercontractility and contribute to resistance during acute schistosomiasis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 298, Issue 6, 2010, Pages

  Marillier, Reece G ^a   Brombacher, Tiroyaone M ^a   Dewals, Benjamin ^a   Leeto, Mosiuoa ^a   Barkhuizen, Mark ^a   Govender, Dhirendra ^b   Kellaway, Lauriston ^c   Horsnell, William G C ^a   Brombacher, Frank ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b Faculty of Health Sciences   (South Africa)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Helminth; Intestine; Murine; Nippostrongylus brasiliensis; Schistosoma mansoni

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE PREDISPOSITION; EXPERIMENTAL INFECTION; FECES CULTURE; FEMALE; HOST RESISTANCE; IMMUNE RESPONSE; INTESTINE CONTRACTION; MORTALITY; MOUSE; MOUSE MUTANT; NONHUMAN; PARASITE IDENTIFICATION; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SEPSIS; SMOOTH MUSCLE FIBER; TH2 CELL; TISSUE INJURY; WEIGHT REDUCTION;

ANIMALS; GASTROINTESTINAL MOTILITY; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; INTERLEUKIN-13; INTESTINES; MICE; MICE, KNOCKOUT; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; RECEPTORS, CELL SURFACE; SCHISTOSOMIASIS MANSONI; SIGNAL TRANSDUCTION; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 77952697466     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00321.2009     Document Type: Article

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