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Volumn 6, Issue , 2010, Pages

Two four-marker haplotypes on 7q36.1 region indicate that the potassium channel gene HERG1 (KCNH2, Kv11.1) is related to schizophrenia: A case control study

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL; ERG1 POTASSIUM CHANNEL; NEUROLEPTIC AGENT; POTASSIUM CHANNEL HERG;

EID: 77952683860     PISSN: 17449081     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-9081-6-27     Document Type: Article
Times cited : (29)

References (66)
  • 1
    • 46449113977 scopus 로고    scopus 로고
    • Schizophrenia, "just the facts": what we know in 2008. 2. Epidemiology and etiology
    • 10.1016/j.schres.2008.04.011, 18514488
    • Tandon R, Keshavan MS, Nasrallah HA. Schizophrenia, "just the facts": what we know in 2008. 2. Epidemiology and etiology. Schizophr Res 2008, 102:1-18. 10.1016/j.schres.2008.04.011, 18514488.
    • (2008) Schizophr Res , vol.102 , pp. 1-18
    • Tandon, R.1    Keshavan, M.S.2    Nasrallah, H.A.3
  • 2
    • 56049085809 scopus 로고    scopus 로고
    • Schizophrenia, "just the facts": what we know in 2008. Part 3: neurobiology
    • 10.1016/j.schres.2008.07.020, 18799287
    • Keshavan MS, Tandon R, Boutros NN, Nasrallah HA. Schizophrenia, "just the facts": what we know in 2008. Part 3: neurobiology. Schizophr Res 2008, 106:89-107. 10.1016/j.schres.2008.07.020, 18799287.
    • (2008) Schizophr Res , vol.106 , pp. 89-107
    • Keshavan, M.S.1    Tandon, R.2    Boutros, N.N.3    Nasrallah, H.A.4
  • 3
    • 50049107823 scopus 로고    scopus 로고
    • Schizophrenia: from developmental deviance to dopamine dysregulation
    • 10.1016/j.euroneuro.2008.04.002, 18499406
    • Murray RM, Lappin J, Di Forti M. Schizophrenia: from developmental deviance to dopamine dysregulation. Eur Neuropsychopharmacol 2008, 18(Suppl 3):S129-S134. 10.1016/j.euroneuro.2008.04.002, 18499406.
    • (2008) Eur Neuropsychopharmacol , vol.18 , Issue.SUPPL 3
    • Murray, R.M.1    Lappin, J.2    Di Forti, M.3
  • 4
    • 53549120606 scopus 로고    scopus 로고
    • Emerging drugs for schizophrenia
    • 10.1517/14728214.13.3.479, 18764724
    • Agid O, Kapur S, Remington G. Emerging drugs for schizophrenia. Expert Opin Emerg Drugs 2008, 13:479-495. 10.1517/14728214.13.3.479, 18764724.
    • (2008) Expert Opin Emerg Drugs , vol.13 , pp. 479-495
    • Agid, O.1    Kapur, S.2    Remington, G.3
  • 5
    • 33646818313 scopus 로고    scopus 로고
    • Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia
    • 10.2165/00023210-200620050-00004, 16696579
    • Horacek J, Bubenikova-Valesova V, Kopecek M, Palenicek T, Dockery C, Mohr P, Hoschl C. Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia. CNS Drugs 2006, 20:389-409. 10.2165/00023210-200620050-00004, 16696579.
    • (2006) CNS Drugs , vol.20 , pp. 389-409
    • Horacek, J.1    Bubenikova-Valesova, V.2    Kopecek, M.3    Palenicek, T.4    Dockery, C.5    Mohr, P.6    Hoschl, C.7
  • 6
    • 11844286960 scopus 로고    scopus 로고
    • Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies
    • 10.1016/j.eurpsy.2004.11.003, 15642439
    • Abi-Dargham A, Laruelle M. Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies. Eur Psychiatry 2005, 20:15-27. 10.1016/j.eurpsy.2004.11.003, 15642439.
    • (2005) Eur Psychiatry , vol.20 , pp. 15-27
    • Abi-Dargham, A.1    Laruelle, M.2
  • 7
    • 34047130777 scopus 로고    scopus 로고
    • Schizophrenia: new pathological insights and therapies
    • 10.1146/annurev.med.58.060904.084114, 16903799
    • Jarskog LF, Miyamoto S, Lieberman JA. Schizophrenia: new pathological insights and therapies. Annu Rev Med 2007, 58:49-61. 10.1146/annurev.med.58.060904.084114, 16903799.
    • (2007) Annu Rev Med , vol.58 , pp. 49-61
    • Jarskog, L.F.1    Miyamoto, S.2    Lieberman, J.A.3
  • 8
    • 34547645771 scopus 로고    scopus 로고
    • The role of dopamine for the pathophysiology of schizophrenia
    • 10.1080/09540260701502468, 17671867
    • Meisenzahl EM, Schmitt GJ, Scheuerecker J, Moller HJ. The role of dopamine for the pathophysiology of schizophrenia. Int Rev Psychiatry 2007, 19:337-345. 10.1080/09540260701502468, 17671867.
    • (2007) Int Rev Psychiatry , vol.19 , pp. 337-345
    • Meisenzahl, E.M.1    Schmitt, G.J.2    Scheuerecker, J.3    Moller, H.J.4
  • 9
    • 46749102129 scopus 로고    scopus 로고
    • Antipsychotic-induced extrapyramidal symptoms and their management
    • 10.1517/14656566.9.9.1451, 18518777
    • Dayalu P, Chou KL. Antipsychotic-induced extrapyramidal symptoms and their management. Expert Opin Pharmacother 2008, 9:1451-1462. 10.1517/14656566.9.9.1451, 18518777.
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 1451-1462
    • Dayalu, P.1    Chou, K.L.2
  • 10
    • 34547110810 scopus 로고    scopus 로고
    • Antipsychotic efficacy: relationship to optimal D2-receptor occupancy
    • 10.1016/j.eurpsy.2007.02.005, 17419008
    • Pani L, Pira L, Marchese G. Antipsychotic efficacy: relationship to optimal D2-receptor occupancy. Eur Psychiatry 2007, 22:267-275. 10.1016/j.eurpsy.2007.02.005, 17419008.
    • (2007) Eur Psychiatry , vol.22 , pp. 267-275
    • Pani, L.1    Pira, L.2    Marchese, G.3
  • 11
    • 14544268139 scopus 로고    scopus 로고
    • QT prolongation through hERG K+ channel blockade: current knowledge and strategies for the early prediction during drug development
    • 10.1002/med.20019, 15389727
    • Recanatini M, Poluzzi E, Masetti M, Cavalli A, De Ponti F. QT prolongation through hERG K+ channel blockade: current knowledge and strategies for the early prediction during drug development. Med Res Rev 2005, 25:133-166. 10.1002/med.20019, 15389727.
    • (2005) Med Res Rev , vol.25 , pp. 133-166
    • Recanatini, M.1    Poluzzi, E.2    Masetti, M.3    Cavalli, A.4    De Ponti, F.5
  • 12
    • 23644450590 scopus 로고    scopus 로고
    • Genetics of acquired long QT syndrome
    • 10.1172/JCI25539, 1180553, 16075043
    • Roden DM, Viswanathan PC. Genetics of acquired long QT syndrome. J Clin Invest 2005, 115:2025-2032. 10.1172/JCI25539, 1180553, 16075043.
    • (2005) J Clin Invest , vol.115 , pp. 2025-2032
    • Roden, D.M.1    Viswanathan, P.C.2
  • 13
    • 23944521812 scopus 로고    scopus 로고
    • Antipsychotic drugs and QT prolongation
    • 10.1097/01.yic.0000166405.49473.70, 16096514
    • Stollberger C, Huber JO, Finsterer J. Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol 2005, 20:243-251. 10.1097/01.yic.0000166405.49473.70, 16096514.
    • (2005) Int Clin Psychopharmacol , vol.20 , pp. 243-251
    • Stollberger, C.1    Huber, J.O.2    Finsterer, J.3
  • 14
    • 0028292927 scopus 로고
    • A family of potassium channel genes related to eag in Drosophila and mammals
    • 10.1073/pnas.91.8.3438, 43592, 8159766
    • Warmke JW, Ganetzky B. A family of potassium channel genes related to eag in Drosophila and mammals. Proc Natl Acad Sci USA 1994, 91:3438-3442. 10.1073/pnas.91.8.3438, 43592, 8159766.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3438-3442
    • Warmke, J.W.1    Ganetzky, B.2
  • 16
    • 3142674930 scopus 로고    scopus 로고
    • Functions of erg K+ channels in excitable cells
    • 10.1111/j.1582-4934.2004.tb00256.x, 15090257
    • Schwarz JR, Bauer CK. Functions of erg K+ channels in excitable cells. J Cell Mol Med 2004, 8:22-30. 10.1111/j.1582-4934.2004.tb00256.x, 15090257.
    • (2004) J Cell Mol Med , vol.8 , pp. 22-30
    • Schwarz, J.R.1    Bauer, C.K.2
  • 17
    • 3342961787 scopus 로고    scopus 로고
    • The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics
    • 10.1007/s00249-004-0419-y, 13680209
    • Vandenberg JI, Torres AM, Campbell TJ, Kuchel PW. The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics. Eur Biophys J 2004, 33:89-97. 10.1007/s00249-004-0419-y, 13680209.
    • (2004) Eur Biophys J , vol.33 , pp. 89-97
    • Vandenberg, J.I.1    Torres, A.M.2    Campbell, T.J.3    Kuchel, P.W.4
  • 18
    • 33645979028 scopus 로고    scopus 로고
    • Structural determinants of potassium channel blockade and drug-induced arrhythmias
    • Wehrens XHT. Structural determinants of potassium channel blockade and drug-induced arrhythmias. Handb Exp Pharmacol 2005, 171:123-157.
    • (2005) Handb Exp Pharmacol , vol.171 , pp. 123-157
    • Wehrens, X.H.T.1
  • 19
    • 30444457229 scopus 로고    scopus 로고
    • Potassium channels: multiplicity and challenges
    • 10.1038/sj.bjp.0706447, 1760724, 16402122
    • Jenkinson DH. Potassium channels: multiplicity and challenges. Br J Pharmacol 2006, 147(Suppl 1):S63-S71. 10.1038/sj.bjp.0706447, 1760724, 16402122.
    • (2006) Br J Pharmacol , vol.147 , Issue.SUPPL 1
    • Jenkinson, D.H.1
  • 20
    • 1542298958 scopus 로고    scopus 로고
    • Pharmacology of cardiac potassium channels
    • 10.1016/j.cardiores.2003.12.026, 15023549
    • Tamargo J, Caballero R, Gomez R, Valenzuela C, Delpon E. Pharmacology of cardiac potassium channels. Cardiovasc Res 2004, 62:9-33. 10.1016/j.cardiores.2003.12.026, 15023549.
    • (2004) Cardiovasc Res , vol.62 , pp. 9-33
    • Tamargo, J.1    Caballero, R.2    Gomez, R.3    Valenzuela, C.4    Delpon, E.5
  • 21
    • 0035144415 scopus 로고    scopus 로고
    • Erg1, erg2 and erg3 K channel subunits are able to form heteromultimers
    • 10.1007/s004240000467, 11212207
    • Wimmers S, Wulfsen I, Bauer CK, Schwarz JR. Erg1, erg2 and erg3 K channel subunits are able to form heteromultimers. Pflugers Arch 2001, 441:450-455. 10.1007/s004240000467, 11212207.
    • (2001) Pflugers Arch , vol.441 , pp. 450-455
    • Wimmers, S.1    Wulfsen, I.2    Bauer, C.K.3    Schwarz, J.R.4
  • 22
    • 0141481906 scopus 로고    scopus 로고
    • Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system
    • 10.1002/cne.10886, 14515244
    • Papa M, Boscia F, Canitano A, Castaldo P, Sellitti S, Annunziato L, Taglialatela M. Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system. J Comp Neurol 2003, 466:119-135. 10.1002/cne.10886, 14515244.
    • (2003) J Comp Neurol , vol.466 , pp. 119-135
    • Papa, M.1    Boscia, F.2    Canitano, A.3    Castaldo, P.4    Sellitti, S.5    Annunziato, L.6    Taglialatela, M.7
  • 23
    • 0344876518 scopus 로고    scopus 로고
    • Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3
    • 10.1016/S1567-133X(03)00124-8, 14643686
    • Polvani S, Masi A, Pillozzi S, Gragnani L, Crociani O, Olivotto O, Becchetti A, Wanke E, Arcangeli A. Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3. Gene Expr Patterns 2003, 3:767-776. 10.1016/S1567-133X(03)00124-8, 14643686.
    • (2003) Gene Expr Patterns , vol.3 , pp. 767-776
    • Polvani, S.1    Masi, A.2    Pillozzi, S.3    Gragnani, L.4    Crociani, O.5    Olivotto, O.6    Becchetti, A.7    Wanke, E.8    Arcangeli, A.9
  • 24
    • 0031452869 scopus 로고    scopus 로고
    • Identification of two nervous system-specific members of the erg potassium channel gene family
    • Shi W, Wymore RS, Wang HS, Pan Z, Cohen IS, McKinnon D, Dixon JE. Identification of two nervous system-specific members of the erg potassium channel gene family. J Neurosci 1997, 17:9423-9432.
    • (1997) J Neurosci , vol.17 , pp. 9423-9432
    • Shi, W.1    Wymore, R.S.2    Wang, H.S.3    Pan, Z.4    Cohen, I.S.5    McKinnon, D.6    Dixon, J.E.7
  • 26
    • 33745153776 scopus 로고    scopus 로고
    • The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications
    • 10.2174/138161206777585102, 16787254
    • Thomas D, Karle CA, Kiehn J. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications. Curr Pharm Des 2006, 12:2271-2283. 10.2174/138161206777585102, 16787254.
    • (2006) Curr Pharm Des , vol.12 , pp. 2271-2283
    • Thomas, D.1    Karle, C.A.2    Kiehn, J.3
  • 27
    • 33847139443 scopus 로고    scopus 로고
    • The hERG potassium channel as a therapeutic target
    • 10.1517/14728222.11.3.321, 17298291
    • Witchel HJ. The hERG potassium channel as a therapeutic target. Expert Opin Ther Targets 2007, 11:321-336. 10.1517/14728222.11.3.321, 17298291.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 321-336
    • Witchel, H.J.1
  • 28
    • 50249099700 scopus 로고    scopus 로고
    • The hERG potassium channel and hERG screening for drug-induced torsades de pointes
    • 10.1016/j.pharmthera.2008.05.009, 18616963
    • Hancox JC, McPate MJ, El Harchi A, Zhang YH. The hERG potassium channel and hERG screening for drug-induced torsades de pointes. Pharmacol Ther 2008, 119:118-132. 10.1016/j.pharmthera.2008.05.009, 18616963.
    • (2008) Pharmacol Ther , vol.119 , pp. 118-132
    • Hancox, J.C.1    McPate, M.J.2    El Harchi, A.3    Zhang, Y.H.4
  • 29
    • 50149112857 scopus 로고    scopus 로고
    • The QT syndromes: long and short
    • 10.1016/S0140-6736(08)61307-0, 18761222
    • Morita H, Wu J, Zipes DP. The QT syndromes: long and short. Lancet 2008, 372:750-763. 10.1016/S0140-6736(08)61307-0, 18761222.
    • (2008) Lancet , vol.372 , pp. 750-763
    • Morita, H.1    Wu, J.2    Zipes, D.P.3
  • 30
    • 61849180389 scopus 로고    scopus 로고
    • Human ether-a-go-go-related gene (hERG) K+ channels: function and dysfunction
    • 10.1016/j.pbiomolbio.2008.10.006, 19027781
    • Perrin MJ, Subbiah RN, Vandenberg JI, Hill AP. Human ether-a-go-go-related gene (hERG) K+ channels: function and dysfunction. Prog Biophys Mol Biol 2008, 98:137-148. 10.1016/j.pbiomolbio.2008.10.006, 19027781.
    • (2008) Prog Biophys Mol Biol , vol.98 , pp. 137-148
    • Perrin, M.J.1    Subbiah, R.N.2    Vandenberg, J.I.3    Hill, A.P.4
  • 31
    • 43049112043 scopus 로고    scopus 로고
    • Molecular aspects of the congenital and acquired long QT syndrome: clinical implications
    • 10.1016/j.yjmcc.2008.01.006, 18336833
    • Saenen JB, Vrints JC. Molecular aspects of the congenital and acquired long QT syndrome: clinical implications. J Mol Cell Cardiol 2008, 44:633-646. 10.1016/j.yjmcc.2008.01.006, 18336833.
    • (2008) J Mol Cell Cardiol , vol.44 , pp. 633-646
    • Saenen, J.B.1    Vrints, J.C.2
  • 32
    • 34547747282 scopus 로고    scopus 로고
    • Novel targets for drugs in schizophrenia
    • 10.2174/187152707781387323, 17691983
    • Stone JM, Pilowsky LS. Novel targets for drugs in schizophrenia. CNS Neurol Disord Drug Targets 2007, 6:265-272. 10.2174/187152707781387323, 17691983.
    • (2007) CNS Neurol Disord Drug Targets , vol.6 , pp. 265-272
    • Stone, J.M.1    Pilowsky, L.S.2
  • 33
    • 33846427359 scopus 로고    scopus 로고
    • EPS profiles: the atypical antipsychotics are not all the same
    • 10.1097/00131746-200701000-00003, 17242588
    • Weiden PJ. EPS profiles: the atypical antipsychotics are not all the same. J Psychiatr Pract 2007, 13:13-24. 10.1097/00131746-200701000-00003, 17242588.
    • (2007) J Psychiatr Pract , vol.13 , pp. 13-24
    • Weiden, P.J.1
  • 34
    • 57749100301 scopus 로고    scopus 로고
    • Building a better antipsychotic: receptor targets for the treatment of multiple symptom dimensions of schizophrenia
    • 10.1016/j.nurt.2008.10.020, 19110200
    • Kim DH, Maneen MJ, Stahl SM. Building a better antipsychotic: receptor targets for the treatment of multiple symptom dimensions of schizophrenia. Neurotherapeutics 2009, 6:78-85. 10.1016/j.nurt.2008.10.020, 19110200.
    • (2009) Neurotherapeutics , vol.6 , pp. 78-85
    • Kim, D.H.1    Maneen, M.J.2    Stahl, S.M.3
  • 36
    • 0004235298 scopus 로고
    • Washington DC: American Psychiatric Association, 4, American Psychiatric Association
    • American Psychiatric Association Diagnostic and statistical manual of mental disorders 1994, Washington DC: American Psychiatric Association, 4, American Psychiatric Association.
    • (1994) Diagnostic and statistical manual of mental disorders
  • 37
    • 53049089951 scopus 로고    scopus 로고
    • Long QT syndrome
    • 10.1016/j.cpcardiol.2008.07.002, 18835466
    • Goldenberg I, Zareba W, Moss AJ. Long QT syndrome. Curr Probl Cardiol 2008, 33:629-694. 10.1016/j.cpcardiol.2008.07.002, 18835466.
    • (2008) Curr Probl Cardiol , vol.33 , pp. 629-694
    • Goldenberg, I.1    Zareba, W.2    Moss, A.J.3
  • 38
    • 77954176679 scopus 로고    scopus 로고
    • Rockville: US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research, International Conference on Harmonisation
    • International Conference on Harmonisation Guidance for industry: E14 clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs 2005, Rockville: US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research, International Conference on Harmonisation.
    • (2005) Guidance for industry: E14 clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs
  • 41
    • 34548541233 scopus 로고    scopus 로고
    • KBiosciences
    • KBiosciences. , http://kbioscience.co.uk
  • 42
    • 84870445213 scopus 로고    scopus 로고
    • International HapMap Project
    • International HapMap Project. , http://hapmap.ncbi.nlm.nih.gov
  • 43
    • 46949107578 scopus 로고    scopus 로고
    • Neurobiology of the early course of schizophrenia
    • 10.1586/14737175.8.7.1093, 18590479
    • Jindal RD, Keshavan MS. Neurobiology of the early course of schizophrenia. Expert Rev Neurother 2008, 8:1093-1100. 10.1586/14737175.8.7.1093, 18590479.
    • (2008) Expert Rev Neurother , vol.8 , pp. 1093-1100
    • Jindal, R.D.1    Keshavan, M.S.2
  • 45
    • 24344487347 scopus 로고    scopus 로고
    • Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: evidence for coassembly of different subunits
    • 10.1002/cne.20721, 16127690
    • Guasti L, Cilia E, Crociani O, Hofmann G, Polvani S, Becchetti A, Wanke E, Tempia F, Arcangeli A. Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: evidence for coassembly of different subunits. J Comp Neurol 2005, 491:157-174. 10.1002/cne.20721, 16127690.
    • (2005) J Comp Neurol , vol.491 , pp. 157-174
    • Guasti, L.1    Cilia, E.2    Crociani, O.3    Hofmann, G.4    Polvani, S.5    Becchetti, A.6    Wanke, E.7    Tempia, F.8    Arcangeli, A.9
  • 46
    • 0035399872 scopus 로고    scopus 로고
    • Differential expression of genes encoding subthreshold-operating voltage-gated K+ channels in brain
    • Saganich MJ, Machado E, Rudy B. Differential expression of genes encoding subthreshold-operating voltage-gated K+ channels in brain. J Neurosci 2001, 21:4609-4624.
    • (2001) J Neurosci , vol.21 , pp. 4609-4624
    • Saganich, M.J.1    Machado, E.2    Rudy, B.3
  • 47
  • 48
    • 0036451892 scopus 로고    scopus 로고
    • Biophysical properties of heteromultimeric erg K+ channels
    • 10.1007/s00424-002-0936-4, 12466946
    • Wimmers S, Bauer CK, Schwarz JR. Biophysical properties of heteromultimeric erg K+ channels. Pflugers Arch 2002, 445:423-430. 10.1007/s00424-002-0936-4, 12466946.
    • (2002) Pflugers Arch , vol.445 , pp. 423-430
    • Wimmers, S.1    Bauer, C.K.2    Schwarz, J.R.3
  • 49
    • 66549126615 scopus 로고    scopus 로고
    • Ether-a-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons
    • 10.1113/jphysiol.2009.170548, 2714015, 19359372
    • Hardman RM, Forsythe ID. Ether-a-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons. J Physiol 2009, 587:2487-2497. 10.1113/jphysiol.2009.170548, 2714015, 19359372.
    • (2009) J Physiol , vol.587 , pp. 2487-2497
    • Hardman, R.M.1    Forsythe, I.D.2
  • 50
    • 0030989240 scopus 로고    scopus 로고
    • A novel role for HERG K+ channels: spike-frequency adaptation
    • 10.1111/j.1469-7793.1997.313bn.x, 1159479, 9192303
    • Chiesa N, Rosati B, Arcangeli A, Olivotto M, Wanke E. A novel role for HERG K+ channels: spike-frequency adaptation. J Physiol 1997, 501:313-318. 10.1111/j.1469-7793.1997.313bn.x, 1159479, 9192303.
    • (1997) J Physiol , vol.501 , pp. 313-318
    • Chiesa, N.1    Rosati, B.2    Arcangeli, A.3    Olivotto, M.4    Wanke, E.5
  • 51
    • 67649872815 scopus 로고    scopus 로고
    • Functional properties of human neuronal Kv11 channels
    • 10.1007/s00424-009-0651-5, 19319565
    • Einarsen K, Calloe K, Grunnet M, Olesen SP, Schmitt N. Functional properties of human neuronal Kv11 channels. Pflugers Arch 2009, 458:689-700. 10.1007/s00424-009-0651-5, 19319565.
    • (2009) Pflugers Arch , vol.458 , pp. 689-700
    • Einarsen, K.1    Calloe, K.2    Grunnet, M.3    Olesen, S.P.4    Schmitt, N.5
  • 52
    • 54049090005 scopus 로고    scopus 로고
    • ERG voltage-gated K+ channels regulate excitability and discharge dynamics of the medial vestibular nucleus neurones
    • 10.1113/jphysiol.2008.155762, 2614050, 18718985
    • Pessia M, Servettini I, Panichi R, Guasti L, Grassi S, Arcangeli A, Wanke E, Pettorossi VE. ERG voltage-gated K+ channels regulate excitability and discharge dynamics of the medial vestibular nucleus neurones. J Physiol 2008, 586:4877-4890. 10.1113/jphysiol.2008.155762, 2614050, 18718985.
    • (2008) J Physiol , vol.586 , pp. 4877-4890
    • Pessia, M.1    Servettini, I.2    Panichi, R.3    Guasti, L.4    Grassi, S.5    Arcangeli, A.6    Wanke, E.7    Pettorossi, V.E.8
  • 53
    • 0141856608 scopus 로고    scopus 로고
    • Functional roles of an ERG current isolated in cerebellar purkinje neurons
    • 10.1152/jn.00104.2003, 12750425
    • Sacco T, Bruno A, Wanke E, Tempia F. Functional roles of an ERG current isolated in cerebellar purkinje neurons. J Neurophysiol 2003, 90:1817-1828. 10.1152/jn.00104.2003, 12750425.
    • (2003) J Neurophysiol , vol.90 , pp. 1817-1828
    • Sacco, T.1    Bruno, A.2    Wanke, E.3    Tempia, F.4
  • 54
    • 2142710079 scopus 로고    scopus 로고
    • A Ca2+-independent slow afterhyperpolarization in substantia nigra compacta neurons
    • 10.1016/j.neuroscience.2004.02.030, 15120845
    • Nedergaard S. A Ca2+-independent slow afterhyperpolarization in substantia nigra compacta neurons. Neuroscience 2004, 125:841-852. 10.1016/j.neuroscience.2004.02.030, 15120845.
    • (2004) Neuroscience , vol.125 , pp. 841-852
    • Nedergaard, S.1
  • 55
    • 35649002144 scopus 로고    scopus 로고
    • Computational model predicts a role for ERG current in repolarizing plateau potentials in dopamine neurons: implications for modulation of neuronal activity
    • 10.1152/jn.00422.2007, 17699694
    • Canavier CC, Oprisan SA, Callaway JC, Ji H, Shepard PD. Computational model predicts a role for ERG current in repolarizing plateau potentials in dopamine neurons: implications for modulation of neuronal activity. J Neurophysiol 2007, 98:3006-3022. 10.1152/jn.00422.2007, 17699694.
    • (2007) J Neurophysiol , vol.98 , pp. 3006-3022
    • Canavier, C.C.1    Oprisan, S.A.2    Callaway, J.C.3    Ji, H.4    Shepard, P.D.5
  • 57
    • 31144469134 scopus 로고    scopus 로고
    • Structural variation in the human genome
    • 10.1038/nrg1767, 16418744
    • Feuk L, Carson AR, Scherer SW. Structural variation in the human genome. Nat Rev Genet 2006, 7:85-97. 10.1038/nrg1767, 16418744.
    • (2006) Nat Rev Genet , vol.7 , pp. 85-97
    • Feuk, L.1    Carson, A.R.2    Scherer, S.W.3
  • 58
    • 63149198301 scopus 로고    scopus 로고
    • Copy number variants, diseases and gene expression
    • 10.1093/hmg/ddp011, 19297395, Review Issue 1
    • Henrichsen CN, Chaignat E, Reymond A. Copy number variants, diseases and gene expression. Hum Mol Genet 2009, 18(Review Issue 1):R1-R8. 10.1093/hmg/ddp011, 19297395.
    • (2009) Hum Mol Genet , vol.18
    • Henrichsen, C.N.1    Chaignat, E.2    Reymond, A.3
  • 59
    • 6044278223 scopus 로고    scopus 로고
    • Receptor mechanisms in the treatment of schizophrenia
    • 10.1177/026988110401800303, 15358977
    • Reynolds GP. Receptor mechanisms in the treatment of schizophrenia. J Psychopharmacol 2004, 18:340-345. 10.1177/026988110401800303, 15358977.
    • (2004) J Psychopharmacol , vol.18 , pp. 340-345
    • Reynolds, G.P.1
  • 60
    • 12344326514 scopus 로고    scopus 로고
    • Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs
    • 10.1038/sj.mp.4001556, 15289815
    • Miyamoto S, Duncan GE, Marx CE, Lieberman JA. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry 2005, 10:79-104. 10.1038/sj.mp.4001556, 15289815.
    • (2005) Mol Psychiatry , vol.10 , pp. 79-104
    • Miyamoto, S.1    Duncan, G.E.2    Marx, C.E.3    Lieberman, J.A.4
  • 61
    • 0034815059 scopus 로고    scopus 로고
    • The antipsychotic drugs sertindole and pimozide block erg3, a human brain K+ channel
    • 10.1006/bbrc.2001.5434, 11511086
    • Kang J, Chen XL, Rampe D. The antipsychotic drugs sertindole and pimozide block erg3, a human brain K+ channel. Biochem Biophys Res Commun 2001, 286:499-504. 10.1006/bbrc.2001.5434, 11511086.
    • (2001) Biochem Biophys Res Commun , vol.286 , pp. 499-504
    • Kang, J.1    Chen, X.L.2    Rampe, D.3
  • 62
    • 0032410714 scopus 로고    scopus 로고
    • The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG
    • Rampe D, Murawsky MK, Grau J, Lewis EW. The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG. J Pharmacol Exp Ther 1998, 286:788-793.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 788-793
    • Rampe, D.1    Murawsky, M.K.2    Grau, J.3    Lewis, E.W.4
  • 63
    • 35648982545 scopus 로고    scopus 로고
    • Ether-a-go-go-related gene potassium channels: what's all the buzz about?
    • 10.1093/schbul/sbm106, 2779881, 17905786
    • Shepard PD, Canavier CC, Levitan ES. Ether-a-go-go-related gene potassium channels: what's all the buzz about?. Schizophr Bull 2007, 33:1263-1269. 10.1093/schbul/sbm106, 2779881, 17905786.
    • (2007) Schizophr Bull , vol.33 , pp. 1263-1269
    • Shepard, P.D.1    Canavier, C.C.2    Levitan, E.S.3
  • 64
    • 50349096365 scopus 로고    scopus 로고
    • Serotonin and dopamine interactions in psychosis prevention
    • full_text, 18772031
    • Richtand NM, McNamara RK. Serotonin and dopamine interactions in psychosis prevention. Prog Brain Res 2008, 172:141-153. full_text, 18772031.
    • (2008) Prog Brain Res , vol.172 , pp. 141-153
    • Richtand, N.M.1    McNamara, R.K.2
  • 65
    • 65349168411 scopus 로고    scopus 로고
    • Psychosis genetics: modeling the relationship between schizophrenia, bipolar disorder, and mixed (or "schizoaffective") psychoses
    • 10.1093/schbul/sbp020, 2669589, 19329560
    • Craddock N, O'Donovan MC, Owen MJ. Psychosis genetics: modeling the relationship between schizophrenia, bipolar disorder, and mixed (or "schizoaffective") psychoses. Schizophr Bull 2009, 35:482-490. 10.1093/schbul/sbp020, 2669589, 19329560.
    • (2009) Schizophr Bull , vol.35 , pp. 482-490
    • Craddock, N.1    O'Donovan, M.C.2    Owen, M.J.3
  • 66
    • 39449117941 scopus 로고    scopus 로고
    • Intermediate phenotypes in schizophrenia genetics redux: is it a no brainer?
    • 10.1038/sj.mp.4002145, 18285755
    • Tan HY, Callicott JH, Weinberger DR. Intermediate phenotypes in schizophrenia genetics redux: is it a no brainer?. Mol Psychiatry 2008, 13:233-238. 10.1038/sj.mp.4002145, 18285755.
    • (2008) Mol Psychiatry , vol.13 , pp. 233-238
    • Tan, H.Y.1    Callicott, J.H.2    Weinberger, D.R.3


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