Dietary iron restriction or iron chelation protects from diabetes and loss of β-cell function in the obese (ob/ob lep-/-) mouse

American Journal of Physiology - Endocrinology and Metabolism

Volumn 298, Issue 6, 2010, Pages

  Cooksey, Robert C ^a,b   Jones, Deborah ^a   Gabrielsen, Scott ^a   Huang, Jingyu ^a   Simcox, Judith A ^a   Luo, Bai ^a   Soesanto, Yudi ^a   Rienhoff, Hugh ^c,d   Abel, E Dale ^a   McClain, Donald A ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c FerroKin BioSciences   (United States)

^d CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

Insulin secretion; Type 2 diabetes

Indexed keywords

GLUCOSE; INSULIN; IRON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; GLUCOSE TOLERANCE; INSULIN SENSITIVITY; IRON CHELATION; IRON INTAKE; IRON OVERLOAD; IRON RESTRICTION; MOUSE; MOUSE MUTANT; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; CALORIMETRY, INDIRECT; DIABETES MELLITUS, TYPE 2; GLUCOSE; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; IRON CHELATING AGENTS; IRON, DIETARY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; MITOCHONDRIA, HEART; OXYGEN CONSUMPTION; REGRESSION ANALYSIS;

EID: 77952616427     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00022.2010     Document Type: Article

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