Blood letting in high-ferritin type 2 diabetes: Effects on insulin sensitivity and β-cell function

Diabetes

Volumn 51, Issue 4, 2002, Pages 1000-1004

  Fernández Real, José Manuel ^a   Peñarroja, Georgina ^a   Castro, Antoni ^a   García Bragado, Fernando ^a   Hernández Aguado, Ildefonso ^b   Ricart, Wifredo ^a  

^a HOSPITAL JOSEP TRUETA   (Spain)

^b MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; FERRITIN; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN; HEMOGLOBIN A1C; INSULIN; IRON CHELATING AGENT; TRANSFERRIN;

ADULT; AGE; AREA UNDER THE CURVE; ARTICLE; BLOOD PRESSURE; BODY MASS; BODY WEIGHT; CELL FUNCTION; CLINICAL ARTICLE; CLINICAL OBSERVATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FERRITIN BLOOD LEVEL; FOLLOW UP; HEMATOCRIT; HEMOCHROMATOSIS; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PHLEBOTOMY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS;

EID: 0036231727     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.51.4.1000     Document Type: Article

References (31)

1. Carbohydrate homeostasis and pancreatic islet cell function in thalassemia
2. The haemochromatotic human pancreas: A quantitative immunohistochemical and ultrastructural study
3. Hyperinsulinemia in non-cirrhotic haemochromatosis: Impaired hepatic insulin degradation?
4. Insulin resistance and hyperinsulinemia in patients with thalassemia major treated by hypertransfusion
5. Insulin stimulates cellular iron uptake and causes the redistribution on intracellular transferrin receptors to the plasma membrane
6. Serum ferritin as a component of the insulin resistance syndrome
7. Body iron stores are associated with serum insulin and blood glucose concentrations
8. Relation between iron stores and non-insulin-dependent diabetes in men: Case-control study
9. Diabetes and serum ferritin concentration among U.S. adults
10. Iron-chelating therapy and the treatment of thalassenua
11. Factors determining glucose tolerance in patients with thalassemia major
12. Hereditary hemochromatosis: Diagnosis and management in the gene era
13. Response to repeated phlebotomies in patients with non-insulindependent diabetes mellitus
14. Non-insulin-dependent diabetes mellitus and elevated serum ferritin level
15. Increased serum ferritin in insulin-dependent diabetes mellitus: Relation to glycemic control
16. Response of normal subjects to acute blood loss
17. Protein glycation and oxidative stress in diabetes mellitus and ageing
18. Response of pancreatic β-cells to improved insulin sensitivity in women at high risk for type 2 diabetes
19. Effect of phlebotomy on plasma glucose and insulin concentrations
20. Blood donations and risk of coronary heart disease in men
21. Transition metals bind to glycated proteins forming redox active "glycochelates": Implications for the pathogenesis of certain diabetic complications
22. Oxidative stress impairs insulin internalization in endothelial cells in vitro
23. The role of oxidative stress in the onset and progression of diabetes and its complications
24. Insulin resistance and iron overload
25. A new syndrome of liver iron overload with normal transferrin saturation
26. Deferoxamine therapy in high-ferritin diabetes
27. No effect of deferoxamine therapy on glucose homeostasis and insulin secretion in individuals with NIDDM and elevated serum ferritin
28. Diabetes-induced endothelial dysfunction is prevented by long-term treatment with the modified iron chelator, hydroxyethyl starch conjugated-deferoxamine
29. High stored iron levels are associated with excess risk of myocardial infarction in Eastern Finnish men
30. Role of hemochromatosis C282Y and H63D mutations in HFE gene in development of type 2 diabetes and diabetic nephropathy
31. C282Y and H63D mutations of the hemochromatosis candidate gene in type 2 diabetes