Integrated control of pulmonary vascular tone by endothelin and angiotensin II in exercising swine depends on gender

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 6, 2010, Pages

  De Beer, Vincent J ^a   De Graaff, Henri J D ^a   Hoekstra, Maaike ^a   Duncker, Dirk J ^a   Merkus, Daphne ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Exercise; Microcirculation

Indexed keywords

ANGIOTENSIN II; ENDOTHELIN; IRBESARTAN; TEZOSENTAN;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BLOOD VESSEL TONE; CARBON DIOXIDE TENSION; CARDIOPULMONARY HEMODYNAMICS; CONDUCTANCE; CONTROLLED STUDY; EXPERIMENTAL PIG; FEMALE; HEART OUTPUT; LUNG BLOOD VESSEL; LUNG CIRCULATION; MALE; NONHUMAN; OXYGEN SATURATION; PRIORITY JOURNAL; PROTEIN INTERACTION; SEX DIFFERENCE; SYSTEMIC CIRCULATION; TREADMILL EXERCISE; VASCULAR RESISTANCE; VASOCONSTRICTION; VASODILATATION;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BIPHENYL COMPOUNDS; ENDOTHELINS; FEMALE; MALE; MODELS, ANIMAL; PHYSICAL CONDITIONING, ANIMAL; PULMONARY ARTERY; PYRIDINES; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ENDOTHELIN; SEX CHARACTERISTICS; SWINE; TETRAZOLES; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 77952595544     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00459.2009     Document Type: Article

References (40)

1. Chai SY, Fernando R, Peck G, Ye SY, Mendelsohn FA, Jenkins TA, Albiston AL. The angiotensin IV/AT4 receptor. Cell Mol Life Sci 61: 2728-2737, 2004.
2. Chung O, Unger T. Pharmacology of angiotensin receptors and AT1 receptor blockers. Basic Res Cardiol 93, Suppl 2: 15-23, 1998. (Pubitemid 28498125)
3. 1 angiotensin II receptor inhibition in pacing-induced heart failure: effects on left ventricular performance and regional blood flow patterns. J Card Fail 4: 311-323, 1998.
4. Clozel M. Endothelin receptor antagonist. Heart Fail Rev 6: 249-251, 2001.
5. Duncker DJ, Stubenitsky R, Verdouw PD. Role of adenosine in the regulation of coronary blood flow in swine at rest and during treadmill exercise. Am J Physiol Heart Circ Physiol 275: H1663-H1672, 1998. (Pubitemid 128784589)
6. 2 receptors. J Vasc Res 43: 19-26, 2006.
7. Franciosa JA, Baker BJ, Seth L. Pulmonary versus systemic hemodynamics in determining exercise capacity of patients with chronic left ventricular failure. Am Heart J 110: 807-813, 1985. (Pubitemid 16027010)
8. Gomez-Alamillo C, Juncos LA, Cases A, Haas JA, Romero JC. Interactions between vasoconstrictors and vasodilators in regulating hemodynamics of distinct vascular beds. Hypertension 42: 831-836, 2003. (Pubitemid 37237332)
9. Hahn AW, Resink TJ, Scott-Burden T, Powell J, Dohi Y, Buhler FR. Stimulation of endothelin mRNA and secretion in rat vascular smooth muscle cells: a novel autocrine function. Cell Regul 1: 649-659, 1990.
10. Hamed AT, Lokhandwala MF, Jandhyala BS. Comparative evaluation of the factors regulating vascular resistance in dogs, anesthetized with morphine-chloralose or pentobarbital. Arch Int Pharmacodyn Ther 249: 264-274, 1981.
11. Hong HJ, Chan P, Liu JC, Juan SH, Huang MT, Lin JG, Cheng TH. Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells. Cardiovasc Res 61: 159-168, 2004. (Pubitemid 38056692)
12. Hopkins SR, Stary CM, Falor E, Wagner H, Wagner PD, McKirnan MD. Pulmonary gas exchange during exercise in pigs. J Appl Physiol 86: 93-100, 1999. (Pubitemid 29046945)
13. Houweling B, Merkus D, Dekker MM, Duncker DJ. Nitric oxide blunts the endothelin-mediated pulmonary vasoconstriction in exercising swine. J Physiol 568: 629-638, 2005. (Pubitemid 41555462)
14. Kawaguchi H, Sawa H, Yasuda H. Endothelin stimulates angiotensin I to angiotensin II conversion in cultured pulmonary artery endothelial cells. J Mol Cell Cardiol 22: 839-842, 1990. (Pubitemid 20281896)
15. Laplante MA, de Champlain J. The interrelation of the angiotensin and endothelin systems on the modulation of NAD(P)H oxidase. Can J Physiol Pharmacol 84: 21-28, 2006.
16. Lautt WW. Resistance or conductance for expression of arterial vascular tone. Microvasc Res 37: 230-236, 1989. (Pubitemid 19102295)
17. Lipworth BJ, Dagg KD. Vasoconstrictor effects of angiotensin II on the pulmonary vascular bed. Chest 105: 1360-1364, 1994. (Pubitemid 24152588)
18. Massart PE, Hodeige DG, Van Mechelen H, Charlier AA, Ketelslegers JM, Heyndrickx GR, Donckier JE. Angiotensin II and endothelin-1 receptor antagonists have cumulative hypotensive effects in canine Page hypertension. J Hypertens 16: 835-841, 1998. (Pubitemid 28247967)
19. McLaughlin VV, Rich S. Pulmonary hypertension. Curr Probl Cardiol 29: 575-634, 2004.
20. Merkus D, de Beer VJ, Houweling B, Duncker DJ. Control of pulmonary vascular tone during exercise in health and pulmonary hypertension. Pharmacol Ther 119: 242-263, 2008.
21. Merkus D, Haitsma DB, Sorop O, Boomsma F, de Beer VJ, Lamers JM, Verdouw PD, Duncker DJ. Coronary vasoconstrictor influence of angiotensin II is reduced in remodeled myocardium after myocardial infarction. Am J Physiol Heart Circ Physiol 291: H2082-H2089, 2006.
22. Merkus D, Houweling B, Mirza A, Boomsma F, van den Meiracker AH, Duncker DJ. Contribution of endothelin and its receptors to the regulation of vascular tone during exercise is different in the systemic, coronary and pulmonary circulation. Cardiovasc Res 59: 745-754, 2003. (Pubitemid 38368691)
23. Merkus D, Houweling B, van den Meiracker AH, Boomsma F, Duncker DJ. Contribution of endothelin to coronary vasomotor tone is abolished after myocardial infarction. Am J Physiol Heart Circ Physiol 288: H871-H880, 2005. (Pubitemid 40139674)
24. + channel by angiotensin II and endothelin-1. Biochem Pharmacol 49: 1051-1056, 1995.
25. Munzel T, Hink U, Heitzer T, Meinertz T. Role for NADPH/NADH oxidase in the modulation of vascular tone. Ann NY Acad Sci 874: 386-400, 1999. (Pubitemid 29351959)
26. Nickenig G, Baumer AT, Grohe C, Kahlert S, Strehlow K, Rosenkranz S, Stablein A, Beckers F, Smits JF, Daemen MJ, Vetter H, Bohm M. Estrogen modulates AT1 receptor gene expression in vitro and in vivo. Circulation 97: 2197-2201, 1998. (Pubitemid 28265380)
27. O'Leary DS, Johnson JM. Baroreflex control of the rat tail circulation in normothermia and hyperthermia. J Appl Physiol 66: 1234-1241, 1989.
28. Patel HH, Murray F, Insel PA. Caveolae as organizers of pharmacologically relevant signal transduction molecules. Annu Rev Pharmacol Toxicol 48: 359-391, 2008. (Pubitemid 351738158)
29. Reeves JT, Taylor AE. Pulmonary hemodynamics and fluid exchange in the lungs during exercise. In: Handbook of Physiology. Exercise: Regulation and Intergration of Multiple Systems. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 12, chapt. 13p. 585-613.
30. Reeves JT, Grover RF. Pulmonary circulation during exercise. In: Lung Biology in Health and Disease, edited by Weir EK, Reeves JT. New York: Dekker, 1989, p. 107-134.
31. Richard V, Hogie M, Thuillez C. Angiotensin II receptor blockade unmasks a depressor response to endothelin antagonists in rats. Fundam Clin Pharmacol 14: 101-106, 2000. (Pubitemid 30204969)
32. 2 receptors of angiotensin II is found in female than in male spontaneously hypertensive rats. Cardiovasc Res 62: 587-593, 2004.
33. Spieker LE, Noll G, Ruschitzka FT, Luscher TF. Endothelin A receptor antagonists in congestive heart failure: blocking the beast while leaving the beauty untouched? Heart Fail Rev 6: 301-315, 2001. (Pubitemid 32725189)
34. Stewart JM. Role of the lungs in the metabolism of circulating hormones. Chest 59, Suppl: 7S-8S, 1971.
35. Stubenitsky R, Verdouw PD, Duncker DJ. Autonomic control of cardiovascular performance and whole body O2 delivery and utilization in swine during treadmill exercise. Cardiovasc Res 39: 459-474, 1998. (Pubitemid 28346542)
36. Takamura M, Parent R, Cernacek P, Lavallee M. Influence of dual ETA/ETB-receptor blockade on coronary responses to treadmill exercise in dogs. J Appl Physiol 89: 2041-2048, 2000.
37. Toma I, Sax B, Nagy A, Entz L, Jr, Rusvai M, Juhasz-Nagy A, Kekesi V. Intrapericardial angiotensin II stimulates endothelin-1 and atrial natriuretic peptide formation of the in situ dog heart. Exp Biol Med (Maywood) 231: 847-851, 2006. (Pubitemid 43845539)
38. Tsyrlin VA, Gerasimenko VS. Effect of pentobarbital and sodium hydroxybutyrate on central mechanisms regulating vascular tone. Bull Exp Biol Med 76: 1421-1424, 1974.
39. Vatner SF, Braunwald E. Cardiovascular control mechanisms in the conscious state. N Engl J Med 293: 970-976, 1975.
40. Xue B, Pamidimukkala J, Hay M. Sex differences in the development of angiotensin II-induced hypertension in conscious mice. Am J Physiol Heart Circ Physiol 288: H2177-H2184, 2005. (Pubitemid 40604103)