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Volumn 26, Issue 5, 2010, Pages 569-575

Deglycosylation of HIV-1 AE Gp140 enhances the capacity to elicit neutralizing antibodies against the heterologous HIV-1 clade

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; GLYCOPROTEIN GP 140; NEUTRALIZING ANTIBODY; VIRUS ENVELOPE PROTEIN;

EID: 77952561004     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2009.0228     Document Type: Article
Times cited : (6)

References (30)
  • 1
    • 0027978367 scopus 로고
    • Envelope sequence variation, neutralizing antibodies, and primate lentivirus persistence
    • Burns DP, Desrosiers RC: Envelope sequence variation, neutralizing antibodies, and primate lentivirus persistence. Curr Top Microbiol Immunol 1994;188:185-219.
    • (1994) Curr Top Microbiol Immunol , vol.188 , pp. 185-219
    • Burns, D.P.1    Desrosiers, R.C.2
  • 2
    • 0036719574 scopus 로고    scopus 로고
    • Antibodies, viruses and vaccines
    • Burton DR: Antibodies, viruses and vaccines. Nat Rev Immunol 2002;2:706-713.
    • (2002) Nat Rev Immunol , vol.2 , pp. 706-713
    • Burton, D.R.1
  • 3
    • 0037069682 scopus 로고    scopus 로고
    • HIV-1 evades antibody- mediated neutralization through conformational masking of receptor-binding sites
    • Kwong PD, Doyle ML, Casper DJ, et al.: HIV-1 evades antibody- mediated neutralization through conformational masking of receptor-binding sites. Nature 2002;420(6916): 678-682.
    • (2002) Nature , vol.420 , Issue.6916 , pp. 678-682
    • Kwong, P.D.1    Doyle, M.L.2    Casper, D.J.3
  • 4
    • 0037456827 scopus 로고    scopus 로고
    • Antibody neutralization and escape by HIV-1
    • Wei X, Decker JM, Wang S, et al.: Antibody neutralization and escape by HIV-1. Nature 2003;422:307-312.
    • (2003) Nature , vol.422 , pp. 307-312
    • Wei, X.1    Decker, J.M.2    Wang, S.3
  • 5
    • 0000604395 scopus 로고    scopus 로고
    • The neutralizing antibody response to HIV-1: Viral evasion and escape from humoral immunity
    • Parren PW, Moore JP, Burton DR, et al.: The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity. AIDS 1999;13(Suppl A):S137-162.
    • (1999) AIDS , vol.13 , Issue.SUPPL. A
    • Parren, P.W.1    Moore, J.P.2    Burton, D.R.3
  • 6
    • 0032546844 scopus 로고    scopus 로고
    • The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens
    • Wyatt R, Sodroski J: The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. Science 1998;280(5371): 1884-1888.
    • (1998) Science , vol.280 , Issue.5371 , pp. 1884-1888
    • Wyatt, R.1    Sodroski, J.2
  • 7
    • 0032543307 scopus 로고    scopus 로고
    • Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
    • Kwong PD, Wyatt R, Robinson J, et al.: Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 1998; 393(6686):648-659.
    • (1998) Nature , vol.393 , Issue.6686 , pp. 648-659
    • Kwong, P.D.1    Wyatt, R.2    Robinson, J.3
  • 8
    • 0027535672 scopus 로고
    • Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding
    • Li Y, Luo L, Rasool N, Kang CY: Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding. J Virol 1993; 67: 584-588.
    • (1993) J Virol , vol.67 , pp. 584-588
    • Li, Y.1    Luo, L.2    Rasool, N.3    Kang, C.Y.4
  • 9
    • 0035199412 scopus 로고    scopus 로고
    • N-linked glycosylation in the V3 region of HIV type 1 surface antigen modulates coreceptor usage in viral infection
    • Li Y, Rey-Cuille MA, Hu SL: N-linked glycosylation in the V3 region of HIV type 1 surface antigen modulates coreceptor usage in viral infection. AIDS Res Hum Retrovir 2001; 17:1473-1479.
    • (2001) AIDS Res Hum Retrovir , vol.17 , pp. 1473-1479
    • Li, Y.1    Rey-Cuille, M.A.2    Hu, S.L.3
  • 10
    • 0345016834 scopus 로고
    • Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: Role of carbohydrate in binding and cell fusion
    • Matthews TJ, Weinhold KJ, Lyerly HK, et al.: Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion. Proc Natl Acad Sci USA 1987;84:5424-5428.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5424-5428
    • Matthews, T.J.1    Weinhold, K.J.2    Lyerly, H.K.3
  • 11
    • 0034974149 scopus 로고    scopus 로고
    • N-Linked glycosylation sites adjacent to and within the V1=V2 and the V3 loops of dualtropic human immunodeficiency virus type 1 isolate DH12 gp120 affect coreceptor usage and cellular tropism
    • Ogert RA, Lee MK, Ross W, et al.: N-Linked glycosylation sites adjacent to and within the V1=V2 and the V3 loops of dualtropic human immunodeficiency virus type 1 isolate DH12 gp120 affect coreceptor usage and cellular tropism. J Virol 2001;75(13):5998-6006.
    • (2001) J Virol , vol.75 , Issue.13 , pp. 5998-6006
    • Ogert, R.A.1    Lee, M.K.2    Ross, W.3
  • 12
    • 0028244285 scopus 로고
    • Glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization
    • Back NK, Smit L, De Jong JJ, et al.: Glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization. Virology 1994;199:431-438.
    • (1994) Virology , vol.199 , pp. 431-438
    • Back, N.K.1    Smit, L.2    De Jong, J.J.3
  • 13
    • 0035131175 scopus 로고    scopus 로고
    • Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants
    • Kolchinsky P, Kiprilov E, Sodroski L: Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants. J Virol 2001;75:2041-2050.
    • (2001) J Virol , vol.75 , pp. 2041-2050
    • Kolchinsky, P.1    Kiprilov, E.2    Sodroski, L.3
  • 14
    • 1842562419 scopus 로고    scopus 로고
    • Nlinked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies
    • McCaffrey RA, Saunders C, Hensel M, et al.: Nlinked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies. J Virol 2004;78:3279-3295.
    • (2004) J Virol , vol.78 , pp. 3279-3295
    • McCaffrey, R.A.1    Saunders, C.2    Hensel, M.3
  • 15
    • 0031749469 scopus 로고    scopus 로고
    • A role for carbohydrates in immune evasion in AIDS
    • Reitter JN, Means RE, Desrosiers RC: A role for carbohydrates in immune evasion in AIDS. Nat Med 1998;4(6):679-684.
    • (1998) Nat Med , vol.4 , Issue.6 , pp. 679-684
    • Reitter, J.N.1    Means, R.E.2    Desrosiers, R.C.3
  • 16
    • 0037213247 scopus 로고    scopus 로고
    • Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120
    • Pantophlet R, Saphire EO, Poignard P, et al.: Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120. J Virol 2003; 77: 642-658.
    • (2003) J Virol , vol.77 , pp. 642-658
    • Pantophlet, R.1    Saphire, E.O.2    Poignard, P.3
  • 17
    • 0041920924 scopus 로고    scopus 로고
    • Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition
    • Koch M, Pancera M, Kwong PD, et al.: Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition. Virology 2003;313(2):387-400.
    • (2003) Virology , vol.313 , Issue.2 , pp. 387-400
    • Koch, M.1    Pancera, M.2    Kwong, P.D.3
  • 18
    • 0035100868 scopus 로고    scopus 로고
    • Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1=V2 variable loops
    • Kolchinsky P, Kiprilov E, Bartley P, et al.: Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1=V2 variable loops. J Virol 2001; 75(7):3435-3443.
    • (2001) J Virol , vol.75 , Issue.7 , pp. 3435-3443
    • Kolchinsky, P.1    Kiprilov, E.2    Bartley, P.3
  • 19
    • 0033942750 scopus 로고    scopus 로고
    • V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies
    • Ly A, Stamatatos L. V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies. J Virol 2000;74(15):6769-6776.
    • (2000) J Virol , vol.74 , Issue.15 , pp. 6769-6776
    • Ly, A.1    Stamatatos, L.2
  • 20
    • 37849026069 scopus 로고    scopus 로고
    • Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses
    • Li Y, Cleveland B, Klots I, et al.: Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses. J Virol 2008;82(2):638-651.
    • (2008) J Virol , vol.82 , Issue.2 , pp. 638-651
    • Li, Y.1    Cleveland, B.2    Klots, I.3
  • 21
    • 0030016341 scopus 로고    scopus 로고
    • Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response
    • Bolmstedt A, Sjolander S, Hansen JE, et al.: Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response. J Acquir Immune Defic Syndr Hum Retrovirol 1996;12:213-220.
    • (1996) J Acquir Immune Defic Syndr Hum Retrovirol , vol.12 , pp. 213-220
    • Bolmstedt, A.1    Sjolander, S.2    Hansen, J.E.3
  • 22
    • 67651177546 scopus 로고    scopus 로고
    • Deglycosylation or partial removal of HIV-1 CN54 gp140 V1=V2 domain enhances env-specific T cells
    • Wan Y, Liu L, Wu L, et al.: Deglycosylation or partial removal of HIV-1 CN54 gp140 V1=V2 domain enhances env-specific T cells. AIDS Res Hum Retroviruses 2009;25(6):607-617.
    • (2009) AIDS Res Hum Retroviruses , vol.25 , Issue.6 , pp. 607-617
    • Wan, Y.1    Liu, L.2    Wu, L.3
  • 23
    • 0026555178 scopus 로고
    • Native but not denatured recombinant human immunodeficiency virus type 1 gp120 generates broad-spectrum neutralizing antibodies in baboons
    • Haigwood NL, Nara PL, Brooks E, et al.: Native but not denatured recombinant human immunodeficiency virus type 1 gp120 generates broad-spectrum neutralizing antibodies in baboons. J Virol 1992;66:172-182.
    • (1992) J Virol , vol.66 , pp. 172-182
    • Haigwood, N.L.1    Nara, P.L.2    Brooks, E.3
  • 24
    • 33751226889 scopus 로고    scopus 로고
    • Sequential priming and boosting with heterologous HIV immunogens predominantly stimulated T cell immunity against conserved epitopes
    • Xu J, Ren L, Huang X, et al.: Sequential priming and boosting with heterologous HIV immunogens predominantly stimulated T cell immunity against conserved epitopes. AIDS 2006;20(18):2293-2303.
    • (2006) AIDS , vol.20 , Issue.18 , pp. 2293-2303
    • Xu, J.1    Ren, L.2    Huang, X.3
  • 25
    • 0032543307 scopus 로고    scopus 로고
    • Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
    • Kwong PD, Wyatt R, Robinson J, et al.: Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 1998; 393(6686): 648-659.
    • (1998) Nature , vol.393 , Issue.6686 , pp. 648-659
    • Kwong, P.D.1    Wyatt, R.2    Robinson, J.3
  • 26
    • 34547127164 scopus 로고    scopus 로고
    • Identification of the optimal DC-SIGN binding site on human immunodeficiency virus type 1 gp120
    • Hong PW, Nguyen S, Young S, et al.: Identification of the optimal DC-SIGN binding site on human immunodeficiency virus type 1 gp120. J Virol 2007;81(15):8325-18236
    • (2007) J Virol , vol.81 , Issue.15 , pp. 8325-18236
    • Hong, P.W.1    Nguyen, S.2    Young, S.3
  • 27
    • 0036785596 scopus 로고    scopus 로고
    • Addition of a single gp120 glycan confers increased binding to dendritic cell-specific ICAM-3-grabbing nonintegrin and neutralization escape to human immunodeficiency virus type 1
    • Lue J, Hsu M, Yang D, et al.: Addition of a single gp120 glycan confers increased binding to dendritic cell-specific ICAM-3-grabbing nonintegrin and neutralization escape to human immunodeficiency virus type 1. J Virol 2002;76(20): 10299-10306.
    • (2002) J Virol , vol.76 , Issue.20 , pp. 10299-10306
    • Lue, J.1    Hsu, M.2    Yang, D.3
  • 28
    • 0036113771 scopus 로고    scopus 로고
    • Critical role for Env as well as Gag-Pol in control of a simian-human immunodeficiency virus 89.6P challenge by a DNA prime= recombinant modified vaccinia virus Ankara vaccine
    • Amara RR, Smith JM, Staprans SI, et al.: Critical role for Env as well as Gag-Pol in control of a simian-human immunodeficiency virus 89.6P challenge by a DNA prime= recombinant modified vaccinia virus Ankara vaccine. J Virol 2002;76(12):6138-6146.
    • (2002) J Virol , vol.76 , Issue.12 , pp. 6138-6146
    • Amara, R.R.1    Smith, J.M.2    Staprans, S.I.3
  • 29
    • 34047113368 scopus 로고    scopus 로고
    • Envelope-specific T-helper and cytotoxic T-lymphocyte responses associated with protective immunity to equine infectious anemia virus
    • Tagmyer TL, Craigo JK, Cook SJ, et al.: Envelope-specific T-helper and cytotoxic T-lymphocyte responses associated with protective immunity to equine infectious anemia virus. J Gen Virol 2007;88(Pt 4):1324-1336.
    • (2007) J Gen Virol , vol.88 , Issue.PART 4 , pp. 1324-1336
    • Tagmyer, T.L.1    Craigo, J.K.2    Cook, S.J.3
  • 30
    • 0037225248 scopus 로고    scopus 로고
    • Immunogenicity and ability of variable loop-deleted human immunodeficiency virus type 1 envelope glycoproteins to elicit neutralizing antibodies
    • Kim YB, Han DP, Cao C, et al.: Immunogenicity and ability of variable loop-deleted human immunodeficiency virus type 1 envelope glycoproteins to elicit neutralizing antibodies. Virology 2002;305(1): 124-137.
    • (2002) Virology , vol.305 , Issue.1 , pp. 124-137
    • Kim, Y.B.1    Han, D.P.2    Cao, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.