Salvianolic acid B attenuates hepatocyte apoptosis by regulating mediators in death receptor and mitochondrial pathways

Experimental Biology and Medicine

Volumn 235, Issue 5, 2010, Pages 623-632

  Yan, Xiuchuan ^a   Zhou, Tao ^a   Tao, Yanyan ^a   Wang, Qinglan ^a   Liu, Ping ^a,b   Liu, Chenghai ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Apoptosis; Hepatocytes; High content screening; Mitochondria; Receptors; Salvianolic acid B; Tumor necrosis factor; Type I

Indexed keywords

CASPASE 3; CYTOCHROME C; DEATH RECEPTOR; GALACTOSAMINE; LIPOPOLYSACCHARIDE; PROTEIN BCL 2; SALVIANOLIC ACID B; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR ALPHA RECEPTOR TYPE 1; UNCLASSIFIED DRUG; BENZOFURAN DERIVATIVE; DNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; ENZYME INHIBITION; ENZYME RELEASE; FLOW CYTOMETRY; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER INJURY; LIVER MITOCHONDRION; MALE; MEDIATOR RELEASE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; AGAR GEL ELECTROPHORESIS; ANIMAL; CELL LINE; DNA FRAGMENTATION; INFLAMMATION; LIVER DISEASE; LIVER FUNCTION TEST; METABOLISM; MITOCHONDRION; PATHOLOGY; PATHOPHYSIOLOGY;

MUS;

ANIMALS; APOPTOSIS; BENZOFURANS; CELL LINE; DNA; DNA FRAGMENTATION; ELECTROPHORESIS, AGAR GEL; FLOW CYTOMETRY; GALACTOSAMINE; HEPATOCYTES; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; MICE; MITOCHONDRIA; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77952556468     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2009.009293     Document Type: Article

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