Aquilegia vulgaris L. extract counteracts oxidative stress and cytotoxicity of fumonisin in rats

Toxicon

Volumn 56, Issue 1, 2010, Pages 8-18

  Hassan, Aziza M ^a   Mohamed, Sherif R ^a   El Nekeety, Aziza A ^a   Hassan, Nabila S ^a   Abdel Wahhab, Mosaad A ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Aquilegia vulgaris; Cytotoxicity; DNA; Fumonisins; Liver; Mycotoxins; Oxidative stress

Indexed keywords

ALCOHOL; ANTIOXIDANT; AQUILEGIA VULGARIS EXTRACT; DNA; FUMONISIN; LIPID; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AQUILEGIA; AQUILEGIA VULGARIS; ARTICLE; BONE MARROW TOXICITY; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; ERYTHROCYTE STRUCTURE; FEMALE; HISTOPATHOLOGY; LIPID BLOOD LEVEL; LIPID PEROXIDATION; LIVER LEVEL; LIVER TOXICITY; LOW DRUG DOSE; MICRONUCLEUS TEST; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RANDOM AMPLIFIED POLYMORPHIC DNA; RAT; SPRAGUE DAWLEY RAT; TREATMENT DURATION;

ANIMALS; ANTIOXIDANTS; AQUILEGIA; BONE MARROW CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOODBORNE DISEASES; FUMONISINS; LIPID PEROXIDATION; LIPIDS; LIVER; MEDICINE, TRADITIONAL; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MUTAGENS; MYCOTOXICOSIS; NUCLEIC ACIDS; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANT STEMS; RATS; RATS, SPRAGUE-DAWLEY; SPHINGOSINE;

ANIMALIA; AQUILEGIA VULGARIS; RATTUS;

EID: 77952553027     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.03.006     Document Type: Article

References (109)

1. 1: implication of lipid peroxidation and inhibition of protein and DNA syntheses. Arch. Toxicol. 1998, 72:233-236.
2. Abdel-Wahhab M.A., Ahmed H.H. Protective effects of Korean panax ginseng against chromium VI toxicity and free radical generation in rats. J. Ginseng Res. 2004, 28(1):11-17.
3. Abdel-Wahhab M.A., Aly S.E. Antioxidants and radical scavenging properties of vegetable extracts in rats fed aflatoxin-contaminated diet. J. Agric. Food Chem. 2003, 51:2409-2414.
4. Abdel-Wahhab M.A., Aly S.E. Antioxidant Property of Nagilia Sativa (Black cumin) and Syzygium Aromaticum (Clove) in rats during Aflatoxicosis. J. Appl. Toxicol 2005, 25:218-223.
5. Abdel-Wahhab M.A., Amer H.A., Hassan N.S., Hassan A.M., Naguib K.M. Effects of garlic and cabbage extracts on fuminisin-induced toxicity in rats. J. Egypt. Soc. Toxicol. 2002, 26:1-12.
6. Abdel-Wahhab M.A., Hassan A.M., Amer H.A., Naguib K.M. Prevention of fumonisin-induced maternal and developmental toxicity in rats by certain plant extracts. J. Appl. Toxicol. 2004, 24:469-474.
7. 1 and fumonisins-induced hepatic pre-cancerous lesions in rats. Food Chem. Toxicol. 2010, 48(2):733-742.
8. 1-induced toxicity in primary rat hepatocytes and rat liver in vivo. Toxicology 1998, 131(2-3):121-131.
9. Adamska T., Młynarczyk W., Jodynis-Liebert J., Bylka W., Matlawska I. Hepatoprotective effect of the extract and isocytisoside from Aquilegia vulgaris. Phytother. Res. 2003, 17:691-696.
10. Adler I.D. Cytogenetic tests in mammals. Mutagenecity Testing: A Practical Approach 1984, 298-302. IRL Press, Oxford. S. Venitt, J.M. Parry (Eds.).
11. 1 in Egyptian markets corn. J. Union Arab. Biol. 1997, 4(B):13-26.
12. Aquardo C.F., Noom W.A., Begun S.J. RFLP analysis using heterologous probes. Molecular Genetic Analysis of Populations, a Practical Approach 1992, 115-157. IRL Press, Oxford. A.R. Hoelzel (Ed.).
13. 1. Mutagenesis 2000, 15(6):469-471.
14. Assmann G. Current diagnosis of hyperlipidemias. Internist (Berl.) 1979, 20(11):559-564.
15. Atienzar F., Conradi M., Evenden A., Jha A., Depledge M. Qualitative assessment of genotoxicity using RAPD: comparison of genomic template stability with key fitness parameters in Daphnia magna exposed to benzo(a)pyrene. Environ. Toxicol. Chem. 1999, 18:2275-2282.
16. Atroshi F., Rizzo A., Biese I., Lindberg L.A., Saloniemi H. Effects of feeding T-2 toxin and deoxynivalenol on DNA and GSH contents of brain and spleen of rats supplemented with vitamin E and C and selenium combination. J. Anim. Physiol. Anim. Nutr. 1995, 74:157-164.
17. 1-induced DNA damage in rat liver and spleen: effects of pretreatment with coenzyme Q10, L-carnitine, alpha-tocopherol and selenium. Pharmacol. Res. 1999, 40:459-467.
18. Becerril C., Ferrero M., Sanz F., Castano A. Detection of mitomycin C-induced genetic damage in fish cells by use of RAPD. Mutagenesis 1999, 14:449-456.
19. Bezuidenhout S.C., Gelderblom W.C.A., Gorst-Allman C.P., Horak R.M., Marasas W.F.O., Spiteller G., Vleggaar R. Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme. J. Chem. Soc. Chem. Commun. 1988, 11:743-745.
20. Binder E.M., Tan L.M., Chin L.J., Handl J., Richard J. Worldwide occurrence of mycotoxins in commodities, animal feed and feed ingredients. Fusarium and their Toxins: Mycology, Occurrence, Toxicity, Control and Economic Impact 2007, Anim. Feed Sci. Technol. D.P. Morgavi, R.T. Riley (Eds.).
21. Bolger M., Coker R.D., DiNovi M., Gaylor D., Gelderblom W.C.A., Olsen M., Paster N., Riley R.T., Shephard G., Speijers G.J.A. Fumonisins. Safety Evaluation of Certain Mycotoxins in Foods. FAO Food and Nutrition Paper 74 2001, World Health Organization, Geneva, pp. 103-279.
22. 1. Nat. Toxins 1996, 4:51-52.
23. Bylka W. Isovitexin o-glucosides from Aquilegia vulgaris L. Acta Pol. Pharm. 2001, 58:273-275.
24. Bylka W., Franski R., Stobiecki M. Differentiation between isomeric acacetin-6-C-(6'-O-malonyl) glucoside and acacetin-8-C-(6'-O-malonyl) glucoside by using lower energy CID mass spectra. J. Mass Spectrom. 2002, 37:648-650.
25. Bylka W., Matlawska I. Flavonoids from Aquilegia vulgaris L. part I. Isocytisoside and its derivatives. Acta Pol. Pharm. 1997, 54:331-333.
26. Bylka W., Matlawska I. Flavonoids from Aquilegia vulgaris L. part II. Derivatives of apigenin and luteolin. Acta Pol. Pharm. 1997, 54:335-337.
27. Cetin Y., Bullerman L.B. Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. Food Chem. Toxicol. 2005, 43(5):755-764.
28. Charles C.A., Richmond W. Enzymatic determination of total serum cholesterol. Clin. Chem. 1974, 20(4):470-475.
29. Colvin B.M., Cooley A.J., Beaver R.W. Fumonisin toxicosis in swine: clinical and pathologic findings. J. Vet. Diagn. Invest. 1993, 5:232-236.
30. 1 mycotoxin in cultures of bovine lymphocytes Ital. J. Anim. Sci. 2005, 4:395-402.
31. 1: oxidative status and DNA damage in rats. Toxicology 2007, 232(3):163-169.
32. 1 as an example. Toxicol. Sci. 2001, 61(1):6-17.
33. Drost-Karbowska K., Szaufer-Hajdrych M., Kowalewski Z., Zgorka G. Phenolic acids in Aquilegia vulgaris (Ranuculaceae). Herba Polonica 1996, 42:21-24.
34. Drury R.A., Wallington E.A., Cancerson R. Carlton's Histopathological Techniques 1976, Oxford University Press, Oxford, London, New York. fourth ed.
35. Edrington T.S., Kamps-Holtzapple C.A., Harvey R.B., Kubena L.F., Elissalde M.H., Rottinghaus G.E. Acute hepatic and renal toxicity in lambs dosed with fumonisin containing culture materials. J. Anim. Sci. 1995, 73:508-515.
36. 1 is genotoxic in human derived hepatoma (HepG2) cells. Mutagenesis 2002, 17:257-260.
37. El-Nekeety A.A., El-Kholy W., Abbas N.F., Ebaid A., Amra H.A., Abdel-Wahhab M.A. Efficacy of royal jelly against the oxidative stress of fumonisin in rats. Toxicon 2007, 50:256-269.
38. El-Nekeety A.A., El-Kady M.A., Soliman M.S., Hassan N.S., Abdel-Wahhab M.A. Protective effect of Aquilegia vulgaris (L.) against lead acetate-induced oxidative stress in rats. Food Chem. Toxicol. 2009, 47:2209-2215.
39. Esterbauer H., Schaure R.J., Zollner H. Chemistry and biochemistry of 40 hydroxy-nonenal malonaldehyde and related aldehydes. Free Radic. Biol. Med. 1991, 11:81-128.
40. Ewertowska M., Jodynis-Liebert J., Kujawska M., Adamska T., Matławska I., Szaufer-Hajdrych M. Effect of Aquilegia vulgaris (L.) ethyl ether extract on liver antioxidant defense system in rats. Int. J. Occup. Med. Environ. Health 2009, 22(2):115-123.
41. Fincham J.E., Marasas W.F.O., Taljaard J.J., Kriek N.P., Badenhorst C.J., Gelderblom W.C., Seier J.V., Smuts C.M., Faber M., Weight M.J. Atherogenic effects in a non-human primate of Fusarium moniliforme cultures added to a carbohydrate diet. Atherosclerosis 1992, 94:13-25.
42. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 1972, 18(6):499-502.
43. Gelderblom W.C.A., Jaskiewicz K., Marasas W.F.O., Thiel P.G., Horak R.M., Vleggaar R., Kriek N.P. Fumonisins-novel mycotoxins with cancer promoting activity produced by Fusarium moniliforme. Appl. Environ. Microbiol. 1988, 54:1806-1811.
44. 1 in rats. Carcinogenesis 1991, 12:1247-1251.
45. 1 dosimetry in relation to cancer initiation in rat liver. Carcinogenesis 1994, 15:209-214.
46. Gelderblom W.C.A., Snyman S.D., Abel S., Lebepe-Mazur S., Smuts C.M., van der Westhuizen L., Marasas W.F.O., Victor T.C., Knasmüller S., Huber W. Hepatotoxicity and carcinogenicity of the fumonisins in rats: a review regarding mechanistic implications for establishing risk in humans. Adv. Exp. Med. Biol. 1996, 392:279-296.
47. 1 in rat liver using diethylnitrosamine as cancer initiator. Cancer Lett. 1996, 109:101-108.
48. Gelineau-van Waes J.B., Starr L., Maddox J.R., Aleman F., Voss K., Wilberding J., Riley R.T. Maternal fumonisin exposure and risk for neural tube defects: mechanisms in an in vivo mouse model. Birth Defects Res. Part A: Clin. Mol. Teratol. 2005, 73:487-497.
49. Glenn A.E. Mycotoxigenic Fusarium species in animal feed. Fusarium and their Toxins: Mycology, Occurrence, Toxicity, Control and Economic Impact 2007, Anim. Feed Sci. Technol. D.P. Morgavi, R.T. Riley (Eds.).
50. Hansel R., Keller H., Rimpler H., Schneider G. Bd.4 Drogen A-D. Handbuch der Pharmaceutische Praxis 1992, 312-316. Springer Verlag, Berlin, Heidelberg.
51. 1 treatment activates sphingolipid-metabolizing systems in mouse liver. Toxicol. Sci. 2006, 94(2):388-397.
52. Hoehler D. Ochratoxin a in food and feed: occurrence, legislation and mode of action. Z. Ernahrungswiss 1998, 37:2-12.
53. Jodynis-Liebert J., Matławska I., Bylka W., Murias M. Protective effect of Aquilegia vulgaris (L.) on APAP-induced oxidative stress in rats. J. Ethnopharmacol. 2005, 97(2):351-358.
54. 1-induced hepatic damage in rats. Environ. Toxicol. Pharmacol. 2006, 22:58-63.
55. Jodynis-Liebert J., Adamska T., Ewertowska M., Bylka W., Matławska I. Aquilegia vulgaris extract attenuates carbon tetrachloride-induced liver fibrosis in rats. Exp. Toxicol. Pathol. 2009, 61(5):443-451.
56. 1-treated pig kidney cells. J. Biochem. Toxicol. 1996, 11:121-126.
57. Ketterer B., Beale D., Taylor J.B., Meyer D.J. The genetic relationships and inducibility of soluble glutathione transferases of the rat liver. Biochem. Soc. Trans. 1983, 11(4):466-467.
58. Kim D.H., Yoo H.S., Lee Y.M., Kie J.H., Jang S., Oh S. Elevation of sphinganine 1-phosphate as a predictive biomarker for fumonisin exposure and toxicity in mice. J. Toxicol. Environ. Health A 2006, 69(23):2071-2082.
59. 1, moniliformin and vomitoxin in bacteria and in primary cultures of rat hepatocytes. Mutat. Res. 1997, 391(1-2):39-48.
60. Koracevic D., Koracevic G., Djordjevic V., Andrejevic S., Cosic V. Method for the measurement of antioxidant activity in human fluids. J. Clin. Pathol. 2001, 54(5):356-361.
61. Kritzinger Q., Aveling T.A.S., Marasas W.F.O., Rheeder J.P., van der Westhuizen L., Shepard G.S. Mycoflora and fumonisin mycotoxins associated with cowpea (Vigna unguiculata (L.) Walp) seeds. J. Agric. Food Chem. 2003, 51:2188-2192.
62. Laurent D., Platzer N., Koh F., Sauviat M.P., Pellegrin F. Macrofusin and micromonilin: two new mycotoxins isolated from corn infested by Fusarium moniliforme sheld. Microbiol. Aliments Nutr. 1989, 7:9-16.
63. Ledoux D.R., Brown T.P., Weibking T.S., Rottinghaus G.E. Fumonisin toxicity in broiler chicks. J. Vet. Diagn. Invest. 1992, 4:330-337.
64. Lerda D., Bistoni B.M., Peralta N., Ychari S., Vazquez M., Bosio G. Fumonisins in foods from Cordoba (Argentina), presence and genotoxicity. Food Chem. Toxicol. 2005, 43(5):691-698.
65. Lin C.C., Hsu Y.F., Lin T.C., Hsu F.L., Hsu H.Y. Antioxidant and hepatoprotective activity of punicalagin and punicalin on carbon tetrachloride-induced liver damage in rats. J. Pharm. Pharmacol. 1998, 50:789-794.
66. Marasas W.F.O. Discovery and occurrence of the fumonisins: a historical perspective. Environ. Health Perspect. 2001, 109(Suppl. 2):239-243.
67. 1 isolated from Fusarium moniliforme. Onderstepoort J. Vet. Res. 1988, 55:197-203.
68. 1 on inducible nitric oxide synthase and cyclooxygenase-2 in LPS-stimulated J774A.1 cells. Life Sci. 2000, 67(23):2845-2853.
69. Merrill A.H., Wang E., Vales T.R., Smith E.R., Schroeder J.J., Menaldino D.S., Alexander C., Crane H.M., Xia J., Liotta D.C., Meredith F.I., Riley R.T. Fumonisin toxicity and sphingolipid biosynthesis. Adv. Exp. Med. Biol. 1996, 392:297-306.
70. Missmer S.A., Suarez L., Felkner M., Wang E., Merrill A.E., Rothman K.J., Hendricks K.A. Exposure to fumonisins and the occurrence of neural tube defects along the Texas-Mexico border. Environ. Health Perspect. 2006, 114:237-241.
71. Mitchell J.R., Jollow D.J., Potter W.Z., Gillette J.R., Brodie B.B. Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J. Pharmacol. Exp. Ther. 1973, 187:211-217.
72. 1: cell cycle arrest and DNA base modification in C6 glioma cells. Toxicol. Appl. Pharmacol. 2000, 164:91-96.
73. 3 content of Iowa, Wisconsin and Illinois corn and corn screenings. J. Agric. Food Chem. 1993, 41:263-266.
74. Nishida M., Yoshimitsu H., Okawa M., Nohara T. Four new cycloartane glycosides from Aquilegia vulgaris and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction. Chem. Pharm. Bull. 2003, 51:683-687.
75. Norred W.P., Voss K.A. Toxicity and role of fumonisins in animal and human esophagal cancer. J. Food Prot. 1994, 57:522-527.
76. Osweiler G.D., Kehrli M.E., Stabel J.R., Thurston J.R., Ross P.F., Wilson T.M. Effects of fumonisin-contaminated corn screenings on growth and health of feeder calves. J. Anim. Sci. 1993, 71:459-463.
77. P.D.R. for Herbal Medicines 2000, Medical Economics Company, Montreal, New Jersey, pp. 211-212. second ed.
78. Peares A.G.E. Histochemistry Theoretical and Applied. Analytical Technology 1985, vol. 2. Churchill Living Stone, Edinburgh, London, Melbourne and New York. fourth ed.
79. 1 stimulates cPLA(2) phosphorylation, the arachidonic acid cascade and cAMP production. Carcinogenesis 1999, 20(9):1683-1688.
80. 2 in corn base products from Swiss market. J. Agric. Food Chem. 1992, 40:1352-1354.
81. Plotsky Y., Kaiser M.G., Lamont S.J. Genetic characterization of highly inbred chicken lines by two DNA methods: DNA fingerprinting and polymerase chain reaction using arbitrary primers. Anim. Genet. 1995, 26:163-170.
82. Riley R.T., Showker J.L., Joo H.S., Norred W.P., Chamberlain W.J., Haschek N.M. Alteration of tissue and serum sphingonine to sphingosin ratio: an early biomarker in pigs of exposure to fumonisin containing feeds. Toxicol. Appl. Pharmacol. 1993, 118:105-112.
83. 1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: a new mechanism of nephrotoxicity1,2,3. J. Nutr. 1994, 124:594-603.
84. Rizzo A., Atroshi F., Hirvi T., Saloniemi H. The hemolytic activity of deoxynivalenol and T-2 toxin. Nat. Toxins 1992, 1:106-110.
85. SAS SAS User's Guide: Statistics 1982, SAS Institute, Cary, NC.
86. Schneider W.C. Determination of acids in tissues by pentose analysis. Method Enzymology 1957, 680-684. Academic Press, New York. S.P. Colowick, N.O. Kaplan (Eds.).
87. 1 in Fusarium proliferatum-infected asparagus spears and garlic bulbs from Germany by liquid chromatography-electrospray ionization mass spectrometry. J. Agric. Food Chem. 2002, 50:2778-2881.
88. 1 influenced the effects of arachidonic acid, prostaglandins E2 and A2 on cell cycle progression, apoptosis induction, tyrosine- and CDC2-kinase activity in oesophageal cancer cells. Prostaglandins Leukot. Essent. Fatty Acids 2000, 62(2):75-84.
89. Sharby T.F., Templeton G.E., Beasley J.N., Stephenson E.L. Toxicity resulting from feeding experimentally molded corn to broiler chicks. Poult. Sci. 1992, 52:1007-1014.
90. Sharma D., Appa Rao K.B.C., Totey S.M. Measurement of within and between population genetic variability in quails. Br. Poult. Sci. 2000, 41:29-32.
91. 2 by high performance liquid chromatography with fluorescence detection. J. Liq. Chromatogr. 1990, 13:2077-2087.
92. Silber R., Farber M.C., Papdopoulos E. Glutathione depletion in chronic lymphocytic leukemia B-lymphocytes. Blood 1992, 80:2038-2043.
93. 1 during storage of Brazilian sorghum. J. Agric. Food Chem. 2000, 48:4352-4356.
94. Sokall R.R., Rohlf F.J. Biometry 1961, Ferman, W.H., and Company, pp. 204-252 (Chapter 9).
95. 1 in continuous human and rodent neural cell cultures. Free Radic. Res. 2004, 38(9):933-942.
96. Szaufer-Hajdrych M., Drost-Karbowska K., Kowalewski Z. Phenolic acids and alkaloids in roots of Aquilegia vulgaris L. (Ranunculaceae) part IV. Herba Polonica 1998, 44:165-171.
97. Ueno Y., Aoyama S., Sugiura Y., Wang D.S., Lee U.S., Hirooka E.Y., Hara S., Karki T., Chen G., Yu S.Z. A limited survey of fumonisins in corn and corn-based products in Asian countries. Mycotoxin Res. 1993, 9:27-34.
98. Ueno Y., Iijima K., Wang S.D., Sugiura Y., Sekijima M., Tanaka T., Chen C., Yu S.Z. Fumonisins as a possible contributory risk factor for primary liver cancer: a 3-year study of corn harvested in Haiman, China by HPLC and ELISA. Food Chem. Toxicol. 1997, 35:1143-1150.
99. Visconti A., Boenke A., Doko M.B., Solfrizzo M., Pascale M. Occurrence of fumonisins in Europe and BCR measurement and testing projects. Nat. Toxins 1995, 3:269-274.
100. 1. Nat. Toxins 1993, 1:222-228.
101. Voss K.A., Bacon C.W., Meredith F.I., Norred W.P. Comparative subchronic toxicity studies of Nixtamalized and water-extracted Fusarium moniliforme culture material. Food Chem. Toxicol. 1996, 34:623-632.
102. Wahlefeld A.W. Methods of Enzymatic Analysis 1974, vol. 5:1831-1835. Academic Press, New York. H.U. Bergmeyer (Ed.).
103. Waller R.A., Duncan D.B. A Bayes rule for the symmetric multiple comparison problems. J. Am. Stat. Assoc. 1969, 64:1484-1503.
104. Wang E., Ross P.F., Wilson T.M., Riley R.T., Merrill A.H. Alteration of serum sphingolipids upon dietary exposure of ponies to fumonisins, mycotoxins produced by Fusarium moniliforme. J. Nutr. 1992, 122:1706-1716.
105. Wang J.S., Groopman J.D. DNA damage by mycotoxins. Mutat. Res. 1999, 424(1-2):167-181.
106. 1 on the young broiler chick. Poult. Sci. 1993, 7:266-456.
107. Williams J.K.G., Kubelik A.R., Livak K.J., Rafalsky J.A., Tyngey S.V. DNA polymorphisms amplified by arbitrary primers are useful as genetic markers. Nucleic Acids Res. 1990, 18:6531-6535.
108. Yilmaz S., Aksoy H., Ünal F., Çelik M., Üzbalu D.Y. Genotoxic action of fungicide Conan 5FL (hexaconazole) on mammalian cells in vivo and in vitro. Russ. J. Genet. 2008, 44(3):273-278.
109. 1 on lipid peroxidation in membranes. Biochim. Biophys. Acta 1998, 1371(1):134-142.