메뉴 건너뛰기




Volumn 1798, Issue 6, 2010, Pages 1100-1110

Stability study of the human G-protein coupled receptor, Smoothened

Author keywords

Fluorinated surfactant; GPCR; Hedgehog pathway; Heterologous expression; Smoothened; Thermostability

Indexed keywords

ARGININE; CYCLOPAMINE; GLYCINE; SMOOTHENED PROTEIN; TROMETAMOL;

EID: 77952549881     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2010.02.015     Document Type: Article
Times cited : (19)

References (27)
  • 2
    • 0036366975 scopus 로고    scopus 로고
    • The structural basis of G-protein-coupled receptor function and dysfunction in human diseases
    • Schoneberg T., Schulz A., Gudermann T. The structural basis of G-protein-coupled receptor function and dysfunction in human diseases. Rev. Physiol. Biochem. Pharmacol. 2002, 144:143-227.
    • (2002) Rev. Physiol. Biochem. Pharmacol. , vol.144 , pp. 143-227
    • Schoneberg, T.1    Schulz, A.2    Gudermann, T.3
  • 3
    • 0036676549 scopus 로고    scopus 로고
    • Heterotrimeric G proteins control diverse pathways of transmembrane signaling, a base for drug discovery
    • Landry Y., Gies J.P. Heterotrimeric G proteins control diverse pathways of transmembrane signaling, a base for drug discovery. Mini Rev. Med. Chem. 2002, 2:361-372.
    • (2002) Mini Rev. Med. Chem. , vol.2 , pp. 361-372
    • Landry, Y.1    Gies, J.P.2
  • 6
    • 67650289584 scopus 로고    scopus 로고
    • Mechanisms of Hedgehog pathway activation in cancer and implications for therapy
    • Scales S.J., de Sauvage F.J. Mechanisms of Hedgehog pathway activation in cancer and implications for therapy. Trends Pharmacol. Sci. 2009, 30:303-312.
    • (2009) Trends Pharmacol. Sci. , vol.30 , pp. 303-312
    • Scales, S.J.1    de Sauvage, F.J.2
  • 7
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: paradigms and principles
    • Ingham P.W., McMahon A.P. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 2001, 15:3059-3087.
    • (2001) Genes Dev. , vol.15 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 8
    • 14244253570 scopus 로고    scopus 로고
    • Human receptor Smoothened, a mediator of Hedgehog signalling, expressed in its native conformation in yeast
    • De Rivoyre M., Bonino F., Ruel L., Bidet M., Therond P., Mus-Veteau I. Human receptor Smoothened, a mediator of Hedgehog signalling, expressed in its native conformation in yeast. FEBS Lett. 2005, 579:1529-1533.
    • (2005) FEBS Lett. , vol.579 , pp. 1529-1533
    • De Rivoyre, M.1    Bonino, F.2    Ruel, L.3    Bidet, M.4    Therond, P.5    Mus-Veteau, I.6
  • 9
    • 33749420875 scopus 로고    scopus 로고
    • Human receptors patched and smoothened partially transduce hedgehog signal when expressed in Drosophila cells
    • De Rivoyre M., Ruel L., Varjosalo M., Loubat A., Bidet M., Therond P., Mus-Veteau I. Human receptors patched and smoothened partially transduce hedgehog signal when expressed in Drosophila cells. J. Biol. Chem. 2006, 281:28584-28595.
    • (2006) J. Biol. Chem. , vol.281 , pp. 28584-28595
    • De Rivoyre, M.1    Ruel, L.2    Varjosalo, M.3    Loubat, A.4    Bidet, M.5    Therond, P.6    Mus-Veteau, I.7
  • 10
    • 0026703547 scopus 로고
    • A simple and efficient procedure for transformation of yeasts
    • Elble R. A simple and efficient procedure for transformation of yeasts. Biotechniques 1992, 13:18-20.
    • (1992) Biotechniques , vol.13 , pp. 18-20
    • Elble, R.1
  • 11
    • 77950498036 scopus 로고    scopus 로고
    • Heterologous expression of human membrane receptors in the yeast Saccharomyces cerevisiae
    • Humana Press, Mus-Veteau (Ed.) Heterologous Expression of Membrane Proteins: Methods and Protocols
    • Joubert O., Nehmé R., Bidet M., Mus-Veteau I. Heterologous expression of human membrane receptors in the yeast Saccharomyces cerevisiae. Series: Methods in Molecular Biology 2010, vol. 601:87-103. Humana Press. Mus-Veteau (Ed.).
    • (2010) Series: Methods in Molecular Biology , vol.601 , pp. 87-103
    • Joubert, O.1    Nehmé, R.2    Bidet, M.3    Mus-Veteau, I.4
  • 12
    • 0000511093 scopus 로고
    • New perfluoro alkylated telomeric non ionic surfactants synthesis physicochemical and biological properties
    • Pavia A.A., Pucci B., Riess J.G., Zarif L. New perfluoro alkylated telomeric non ionic surfactants synthesis physicochemical and biological properties. Makromol. Chem. 1992, 193:2505-2517.
    • (1992) Makromol. Chem. , vol.193 , pp. 2505-2517
    • Pavia, A.A.1    Pucci, B.2    Riess, J.G.3    Zarif, L.4
  • 13
    • 0032075801 scopus 로고    scopus 로고
    • Stabilization of integral membrane proteins in aqueous solution using fluorinated surfactants
    • Chabaud E., Barthelemy P., Mora N., Popot J.L., Pucci B. Stabilization of integral membrane proteins in aqueous solution using fluorinated surfactants. Biochimie 1998, 80:515-530.
    • (1998) Biochimie , vol.80 , pp. 515-530
    • Chabaud, E.1    Barthelemy, P.2    Mora, N.3    Popot, J.L.4    Pucci, B.5
  • 14
    • 20444383119 scopus 로고    scopus 로고
    • Functional studies with membrane-bound and detergent-solubilized alpha2-adrenergic receptors expressed in Sf9 cells
    • Sen S., Jaakola V.P., Pirila P., Finel M., Goldman A. Functional studies with membrane-bound and detergent-solubilized alpha2-adrenergic receptors expressed in Sf9 cells. Biochim. Biophys. Acta 2005, 1712:62-70.
    • (2005) Biochim. Biophys. Acta , vol.1712 , pp. 62-70
    • Sen, S.1    Jaakola, V.P.2    Pirila, P.3    Finel, M.4    Goldman, A.5
  • 16
    • 1942532324 scopus 로고    scopus 로고
    • Hemifluorinated surfactants: a non-dissociating environment for handling membrane proteins in aqueous solutions?
    • Breyton C., Chabaud E., Chaudier Y., Pucci B., Popot J.L. Hemifluorinated surfactants: a non-dissociating environment for handling membrane proteins in aqueous solutions?. FEBS Lett. 2004, 564:312-318.
    • (2004) FEBS Lett. , vol.564 , pp. 312-318
    • Breyton, C.1    Chabaud, E.2    Chaudier, Y.3    Pucci, B.4    Popot, J.L.5
  • 17
    • 34147158906 scopus 로고    scopus 로고
    • Fluorinated and hemifluorinated surfactants as alternatives to detergents for membrane protein cell-free synthesis
    • Park K.H., Berrier C., Lebaupain F., Pucci B., Popot J.L., Ghazi A., Zito F. Fluorinated and hemifluorinated surfactants as alternatives to detergents for membrane protein cell-free synthesis. Biochem. J. 2007, 403:183-187.
    • (2007) Biochem. J. , vol.403 , pp. 183-187
    • Park, K.H.1    Berrier, C.2    Lebaupain, F.3    Pucci, B.4    Popot, J.L.5    Ghazi, A.6    Zito, F.7
  • 20
    • 38949158505 scopus 로고    scopus 로고
    • Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form
    • Serrano-Vega M.J., Magnani F., Shibata Y., Tate C.G. Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:877-882.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 877-882
    • Serrano-Vega, M.J.1    Magnani, F.2    Shibata, Y.3    Tate, C.G.4
  • 21
    • 49449114407 scopus 로고    scopus 로고
    • Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor
    • Magnani F., Shibata Y., Serrano-Vega M.J., Tate C.G. Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:10744-10749.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 10744-10749
    • Magnani, F.1    Shibata, Y.2    Serrano-Vega, M.J.3    Tate, C.G.4
  • 23
    • 36049033946 scopus 로고    scopus 로고
    • Hedgehog regulates smoothened activity by inducing a conformational switch
    • Zhao Y., Tong C., Jiang J. Hedgehog regulates smoothened activity by inducing a conformational switch. Nature 2007, 450:252-258.
    • (2007) Nature , vol.450 , pp. 252-258
    • Zhao, Y.1    Tong, C.2    Jiang, J.3
  • 24
    • 0842267080 scopus 로고    scopus 로고
    • Purification and characterization of the recombinant human dopamine D2S receptor from Pichia pastoris
    • de Jong L.A., Grunewald S., Franke J.P., Uges D.R., Bischoff R. Purification and characterization of the recombinant human dopamine D2S receptor from Pichia pastoris. Protein Expr. Purif. 2004, 33:176-184.
    • (2004) Protein Expr. Purif. , vol.33 , pp. 176-184
    • de Jong, L.A.1    Grunewald, S.2    Franke, J.P.3    Uges, D.R.4    Bischoff, R.5
  • 25
    • 12244292640 scopus 로고    scopus 로고
    • Purification and characterization of the human adenosine A(2a) receptor functionally expressed in Escherichia coli
    • Weiss H.M., Grisshammer R. Purification and characterization of the human adenosine A(2a) receptor functionally expressed in Escherichia coli. Eur. J. Biochem. 2002, 269:82-92.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 82-92
    • Weiss, H.M.1    Grisshammer, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.