Endogenous thrombin potential as a novel method for the characterization of procoagulant snake venoms and the efficacy of antivenom

Toxicon

Volumn 56, Issue 1, 2010, Pages 75-85

  Isbister, Geoffrey K ^a,b,c   Woods, David ^a   Alley, Steven ^a   O'Leary, Margaret A ^b   Seldon, Michael ^b   Lincz, Lisa F ^a,b  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

^c MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

Author keywords

Antivenom; Procoagulant venom; Prothrombin activator; Snake; Thrombin potential

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5; CALCIUM; PROCOAGULANT; PROTHROMBIN; SNAKE VENOM; SNAKE VENOM ANTISERUM; THROMBIN;

ARTICLE; AUSTRALIA; BLOOD CLOTTING; BLOOD CLOTTING PARAMETERS; BLOOD CLOTTING TEST; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFICACY; ENDOGENOUS THROMBIN POTENTIAL; ENVENOMATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SYNTHESIS; INTERMETHOD COMPARISON; NONHUMAN; PRIORITY JOURNAL; SPECIES COMPARISON; TOXIN ANALYSIS;

ANTICOAGULANTS; ANTIVENINS; AUSTRALIA; BLOOD COAGULATION; CALCIUM; COAGULANTS; DISSEMINATED INTRAVASCULAR COAGULATION; DRUG DOSAGE CALCULATIONS; ELAPID VENOMS; ENZYME ACTIVATION; HUMANS; KINETICS; PROTHROMBIN; REPTILIAN PROTEINS; SERINE ENDOPEPTIDASES; SNAKE BITES; SNAKE VENOMS; SUBSTRATE SPECIFICITY; THROMBOPLASTIN;

HOPLOCEPHALUS STEPHENSII; NOTECHIS SCUTATUS; OXYURANUS SCUTELLATUS; PSEUDONAJA TEXTILIS; SPILOTES PULLATUS PULLATUS; STORERIA DEKAYI; TROPIDECHIS CARINATUS;

EID: 77952547003     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.03.013     Document Type: Article

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