Neutrophils in biliary atresia. A study on their morphologic distribution and expression of CAP37

Pathology Research and Practice

Volumn 206, Issue 5, 2010, Pages 314-317

  Changho, Sheelah ^a   Ahmed, Atif A ^a  

^a CHILDREN S MERCY HOSPITAL   (United States)

Author keywords

Biliary atresia; CAP37; Immunohistochemistry; Neutrophils

Indexed keywords

AZUROCIDIN; SERINE PROTEINASE;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; BILE DUCT ATRESIA; BILE DUCT OBSTRUCTION; CELL INFILTRATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; COMMON BILE DUCT CYST; DISEASE ASSOCIATION; ENZYME LOCALIZATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER NECROSIS; NEUTROPHIL COUNT; NEWBORN HEPATITIS; PARENCHYMA; PORTOENTEROSTOMY; PROTEIN EXPRESSION;

ANTIMICROBIAL CATIONIC PEPTIDES; BILE DUCTS; BILIARY ATRESIA; BLOOD PROTEINS; CARRIER PROTEINS; CELL COUNT; CELL SHAPE; CHILD; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; NEUTROPHILS;

EID: 77952546781     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2010.02.001     Document Type: Article

References (21)

1. Fischler B., Papadogiannakis N., Nemeth A. Aetiological factors in neonatal cholestasis. Acta Paediatr. 2001, 90:88-92.
2. Mack C.L., Sokol R.J. Unraveling the pathogenesis and etiology of biliary atresia. Pediatr. Res. 2005, 57:87R-94R.
3. Mack C.L. The pathogenesis of biliary atresia: evidence for a virus-induced autoimmune disease. Semin. Liver Dis. 2007, 27:233-242.
4. Bates M.D., Bucuvalas J.C., Alonso M.H., et al. Biliary atresia: pathogenesis and treatment. Semin. Liver Dis. 1998, 18:281-293.
5. Rauschenfels S., Krassmann M., Al-Masri A.N., et al. Incidence of hepatotropic viruses in biliary atresia. Eur. J. Pediatr. 2009, 168:469-476.
6. de Carvalho E., Ivantes C.A.P., Bezerra J.A. Extrahepatic biliary atresia: current concepts and future directions. J. Pediatr. (Rio J.) 2007, 83:105-120.
7. Chardot C. Biliary atresia. Orphanet J. Rare Dis. 2006, 1:28.
8. Kahn E. Biliary atresia revisited. Pediatr. Dev. Pathol. 2004, 7:109-124.
9. Watorek W. Azurocidin-inactive serine proteinase homolog acting as a multifunctional inflammatory mediator. Acta Biochim. Pol. 2003, 50:743-752.
10. Pereira H.A. CAP37, a neutrophil-derived multifunctional inflammatory mediator. J. Leukocyte Biol. 1995, 57:805-812.
11. Bill A.H., Haas J.E., Foster G.L. Biliary atresia: histopathologic observations and reflections upon its natural history. J. Pediatr. Surg. 1977, 12:977-982.
12. Iwanaga M., Nakagawara A., Matsuo S., et al. Impaired polymorphonuclear leukocyte function in biliary atresia: role of bilirubin and bile acids. J. Pediatr. Surg. 1987, 22:967-972.
13. Georgiev P., Jochum W., Heinrich S., et al. Characterization of time-related changes after experimental bile duct ligation. Br. J. Surg. 2008, 95:646-656.
14. Wakabayashi Y., Shimizu H., Kimura F., et al. Mechanism of neutrophil accumulation in sinusoids after extrahepatic biliary obstruction. Hepatogastroenterology 2008, 55:1179-1183.
15. Gujral J.S., Farhood A., Bajt M.L., et al. Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct ligated mice. Hepatology 2003, 38:355-363.
16. Shivakumar P., Campbell K.M., Sabla G.E., et al. Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia. J. Clin. Invest. 2004, 114:322-329.
17. Jafri M., Donnelly B., Bondoc A., et al. Cholangiocyte secretion of chemokines in experimental biliary atresia. J Pediatr. Surg. 2009, 44:500-507.
18. Barnes B.H., Tucker R.M., Wehrmann F., et al. Cholangiocytes as immune modulators in rotavirus-induced murine biliary atresia. Liver Int. 2008, 29:1253-1261.
19. Chuang Y.H., Lan R.Y., Gershwin M.E. The immunopathology of human biliary cell epithelium. Semin. Immunopathol. 2009, 31:323-331.
20. Strazzabosco M., Fabris L., Spirli C. Pathophysiology of cholangiopathies. J. Clin. Gastroenterol. 2005, 39(4 Suppl 2):S90-S102.
21. Strazzabosco M., Spirlí C., Okolicsanyi L. Pathophysiology of the intrahepatic biliary epithelium. J. Gastroenterol. Hepatol. 2000, 15:244-253.