Endothelial cell cytochrome P450 1A1 and 1B1: Up-regulation by shear stress

Endothelium: Journal of Endothelial Cell Research

Volumn 11, Issue 1, 2004, Pages 1-10

  Eskin, Suzanne G ^a   Turner, Nancy A ^a,b   McIntire, Larry V ^a  

^a Emory University   (United States)

^b Rice University   (United States)

Author keywords

CTGF; CYP1A1; CYP1B1; Endothelial cells; ET 1; Shear stress

Indexed keywords

BETA NAPHTHOFLAVONE; CONNECTIVE TISSUE GROWTH FACTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; ENDOTHELIN 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; POLYCYCLIC AROMATIC HYDROCARBON; RNA;

AORTA; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ANALYSIS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN FOLDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RNA TRANSLATION; SHEAR STRESS; UMBILICAL VEIN; UPREGULATION; WESTERN BLOTTING;

BETA-NAPHTHOFLAVONE; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; ENDOTHELIAL CELLS; ENDOTHELIN-1; ENZYME INHIBITORS; HUMANS; IMMEDIATE-EARLY PROTEINS; INFANT, NEWBORN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; REGIONAL BLOOD FLOW; RNA, MESSENGER; STRESS, MECHANICAL; UP-REGULATION;

EID: 1842535528     PISSN: 10623329     EISSN: None     Source Type: Journal    
DOI: 10.1080/10623320490432434     Document Type: Article

References (24)

1. Brooks A.R., Lelkes P.I., and Rubanyi G.M. (2002) Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow. Physiological Genomics, 9, 27-41.
2. Chen B.P.C., Li Y.-S., Zhao Y., Chen K.-D., Li S., Lao J., Yuan S., Shyy J.Y.-J., et al., and Chien S. (2001) DNA microarray analysis of gene expression endothelial cells in response to 24-h shear stress. Physiological Genomics, 7, 55-63.
3. Dekker R.J., van Soest S., Fontijn R.D., Salamanca S., deGroot P.G., VanBavel E., Pannekoek H., et al., and Horrevoets, A.J.G. (2002) Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2). Blood, 100, 1689-1698.
4. Dey A., Jones J.E., and Nebert D.W. (1999) Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hydridization. Biochemical Pharmacology, 58, 525-537.
5. Dichek D., and Quertermous T. (1989) Variability in messenger RNA levels in human umbilical vein endotheliall cells of different lineage and time in culture. In Vitro Cellular and Development Biology, 25, 289-292.
6. Farin F.M., Pohlman T.H., and Omiecinski C.J. (1994) Expression of cytochrome P450s and microsomal epoxide hydrolase in primary cultures of human umbilical vein endothelial cells. Toxicology and Applied Pharmacology, 124, 1-9.
7. Fisslthaler B., Hinsch N., Chataigneau T., Popp T., Kiss L., Busse R., et al., and Fleming I. (2000) Nifedipine increases cytochrome P4502C expression and endothelium-derived hyperpolarizing factor-mediated responses in coronary arteries. Hypertension, 36, 270-275.
8. Fleming I. (2001) Cytochrome p450 and vascular homeostasis. Circulation Research, 89, 753-762.
9. Frangos J.A., McIntire L.V., and Eskin S.G. (1988) Shear stress induced stimulation of mammalian cell metabolism. Biotechnology and Bioengineering, 32, 1053-1060.
10. Garcia-Cardena G., Comander J., Anderson K.R., Blackman B.R., et al., and Gimbrone, M.A. Jr. (2001) Biomechanical activation of vascular endotohelium as a determinant of its functional phenotype. Proceedings of the National Academy of Sciences of the United States of America, 98, 4478-4485.
11. Hahn A., Heusinger-Ribiero J., Lanz T., Zenkel S., et al., and Goppelt-Struebe, M. (2000) Induction of connective tissue growth factor by activation of heptahelical receptors. Modulation by rho proteins and the actin cytoskeleton. Journal of Biological Chemistry, 275, 37429-37435.
12. Lekas P., Tin K.L., Lee C., et al., and Prokipcak R.D. (2000) The human cytochrome P450 1A1 mRNA is rapidly degraded in HepG2 cells. Archives of Biochemistry and Biophysics, 384, 311-318.
13. Libby R.T., Smith R.S., Savinova O.V., Zabaleta A., Martin J.E., Gonzalez F.J., et al., and John S.W. (2003) Modification of ocular defects in mouse developmental glaucoma models by tyrosinase. Science, 299, 1578-1581.
14. McCormick S.M., Eskin S.G., McIntire L.V., Teng C.L., Lu C.-M., Russell C.G., et al., and Chittur K.K. (2001) DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells. Proceedings of the National Academy of Sciences of the United States of America, 98, 8955-8960.
15. Nguyen K.T., Frye S.R., Eskin S.G., Patterson C., Runge M.S., et al., and McIntire L.V. (2001) Cyclic strain increases protease-activated receptor-1 expression in vascular smooth muscle cells. Hypertension, 38, 1038-1043.
16. Oemar B.S., Werner A., Garnier J.M., Do D.D., Godoy N., Nauck M., Marz W., Rupp J., Pech M., et al., and Luscher T.F. (1997) Human connective tissue growth factor is expressed in advanced atherosclerotic lesions. Circulation, 95, 831-839.
17. Ranta V., Orpana A., Mikkola T., Ylikorkala O., et al., and Viinikka L. (1997) Culturing of human vascular endothelial cells strongly affects their endothelin-1 and prostacyclin production. Molecular and Cellular Biochemistry, 177, 251-255.
18. Resnick N., Collins T., Atkinson W., Bothron D.T., Dewey C.F.J., et al., and Gimbrone M.A.J. (1993) Platelet-derived growth factor B chain promoter contains a cis-acting shear-stress-responsive element. Proceedings of the National Academy of Sciences of the United States of America, 90, 4591-4595.
19. Sharefkin J.B., Diamond S.L., Eskin S.G., McIntire L.V., et al., and Dieffenbach C.W. (1991) Fluid flow decreases preproendothelin mRNA levels and suppresses endothelin-1 peptide release in cultured human endothelial cells. Journal of Vascular Surgery, 14, 1-9.
20. Shelton D.N., Chang E., Whittier P.S., Choi D., et al., and Funk W.D. (1999) Microarray analysis of replicative senescence. Current Biology, 9, 939-945.
21. Smeets E.F., v. Asmuth E.J.U., v.d. Linden C.J., Leeuwenberg J.F.M., et al., and Buurman W.A. (1992) A comparison of substrates for human umbilical vein endothelial cell culture. Biotechnic Histochemistry, 67, 241-250.
22. Thum T., Haverich A., and Borlak J. (2000) Cellular dediferentiation of endothelium is linked to activation and silencing of certain nuclear transcription factors: Implications for endothelial dysfunction and vascular biology. FASEB Journal, 14, 740-751.
23. Topper J.N., Cai J., Falb D., et al., and Gimbrone M.A.J. (1996) Identification of vascular endothelial cells differentially responsive to fluid mechanical stimuli: Cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proceedings of the National Academy of Sciences of the United States of America, 93, 10417-10422.
24. Whitlock J.P. (1999) Induction of cytochrome P4501A1. Annual Review of Pharmacology and Toxicology, 39, 103-125.