Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts

Circulation: Cardiovascular Genetics

Volumn 3, Issue 1, 2010, Pages 78-87

  Agnetti, Giulio ^a,b   Kaludercic, Nina ^b   Kane, Lesley A ^a   Elliott, Steven T ^c   Guo, Yurong ^c   Chakir, Khalid ^c   Samantapudi, Daya ^c   Paolocci, Nazareno ^c,d   Tomaselli, Gordon F ^c   Kass, David A ^c   Van Eyk, Jennifer E ^a,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PERUGIA   (Italy)

Author keywords

ATP synthase; Cardiac resynchronization therapy; Mitochondria; Proteomics

Indexed keywords

BRANCHED CHAIN AMINO ACID; CHAPERONE; GLUTAMIC ACID; MALIC ACID; MITOCHONDRIAL PROTEIN; PROTEINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE BETA SUBUNIT; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; UNCLASSIFIED DRUG; PROTEOME; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXYLATION; CARDIAC RESYNCHRONIZATION THERAPY; CITRIC ACID CYCLE; CONTROLLED STUDY; DOG; ENERGY METABOLISM; ENZYME MODIFICATION; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE; MITOCHONDRIAL RESPIRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEOMICS; REGULATORY MECHANISM; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; TWO DIMENSIONAL GEL ELECTROPHORESIS; ANIMAL; BIOSYNTHESIS; HEART MITOCHONDRION; HEART PACING; HEART VENTRICLE; METABOLISM; PATHOPHYSIOLOGY; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; ANIMALS; ATP SYNTHETASE COMPLEXES; CARDIAC PACING, ARTIFICIAL; CITRIC ACID CYCLE; DOGS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HEART FAILURE; HEART VENTRICLES; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOME; PROTEOMICS;

EID: 77952534157     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.109.871236     Document Type: Article

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