Regulation of sarcolemmal transport of substrates in the healthy and diseased heart

Cardiovascular Drugs and Therapy

Volumn 20, Issue 6, 2006, Pages 471-476

  Glatz, Jan F C ^a   Bonen, Arend ^b   Ouwens, D Margriet ^c   Luiken, Joost J F P ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF GUELPH   (Canada)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

CD36; Diabetic cardiomyopathy; Energy production; Fatty acid transporter; Glucose transporter; GLUT4; Sarcolemmal transport

Indexed keywords

CD36 ANTIGEN; FATTY ACID; FATTY ACID BINDING PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN;

ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID TRANSPORT; GENE MUTATION; GLUCOSE TRANSPORT; HEART CONTRACTION; HEART DISEASE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HORMONE ACTION; HUMAN; INSULIN RESISTANCE; MUSCLE BIOPSY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; SARCOLEMMA; SIGNAL TRANSDUCTION; TRANSPORT KINETICS; UPREGULATION;

ANIMALS; BIOLOGICAL TRANSPORT; ENERGY METABOLISM; FATTY ACIDS; GLUCOSE; HEART DISEASES; HUMANS; MEMBRANE TRANSPORT PROTEINS; MYOCARDIUM; SARCOLEMMA; SIGNAL TRANSDUCTION;

EID: 33846408278     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10557-006-0582-8     Document Type: Review

References (30)

1. Stanley WC, Recchia FA, Lopaschuk GD. Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 2005;85:1093-129.
2. Kagaya Y, Kanno Y, Takeyama D, Ishide N, Maruyama Y, Takahashi T, et al. Effects of long-term pressure overload on regional myocardial glucose and free fatty acid uptake in rats. A quantitative autoradiographic study. Circulation 1990;81:1353-61.
3. Carley AN, Severson DL. Fatty acid metabolism is enhanced in type 2 diabetic hearts. Biochim Biophys Acta 2005;1734:112-26.
4. Binas B, Danneberg H, McWhir J, Mullins L, Clark AJ. Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization. FASEB J 1999;13:805-12.
5. Kelly DP, Strauss AW. Inherited cardiomyopathies. N Engl J Med 1994;330:913-9.
6. Hartil K, Charron MJ. Genetic modification of the heart: transgenic modification of cardiac lipid and carbohydrate utilization. J Mol Cell Cardiol 2005;39:581-93.
7. Coort SLM, Bonen A, Van der Vusse GJ, Glatz JFC, Luiken JJFP. Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: role of sarcolemmal substrate transporters. Mol Cell Biochem 2006; (in press).
8. Glatz JFC, Bonen A, Luiken JJFP. Exercise and insulin increase muscle fatty acid uptake by recruiting putative fatty acid transporters to the sarcolemma. Curr Opin Clin Nutr Metab Care 2002;5:365-70.
9. Zorzano A, Sevilla L, Camps M, Becker C, Meyer J, Kammermeier H, et al. Regulation of glucose transport, and glucose transporters expression and trafficking in the heart: studies in cardiac myocytes. Am J Cardiol 1997;80:65A-76A.
10. Glatz JF, Luiken JJ, van Nieuwenhoven FA, Van der Vusse GJ. Molecular mechanism of cellular uptake and intracellular translocation of fatty acids. Prostaglandins Leukot Essent Fatty Acids 1997;57:3-9.
11. Hamilton JA, Guo W, Kamp F. Mechanism of cellular uptake of long-chain fatty acids: do we need cellular proteins? Mol Cell Biochem 2002;239:17-23.
12. Luiken JJFP, Coort SLM, Koonen DPY, Van der Horst DJ, Bonen A, Zorzano A, et al. Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters. Eur J Physiol 2004;448:1-15.
13. Chabowski A, Coort SL, Calles-Escandon J, Tanond NN, Glatz JF, Luiken JJ, et al. The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR. FEBS Lett 2005;579:2428-32.
14. Koonen DPY, Glatz JFC, Bonen A, Luiken JJFP. Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle. Biochim Biophys Acta 2005;1736:163-80.
15. Fischer Y, Thomas J, Sevilla L, Munoz P, Becker C, Holman G, et al. Insulin-induced recruitment of glucose transporter 4 (GLUT4) and GLUT1 in isolated rat cardiac myocytes. Evidence of the existence of different intracellular GLUT4 vesicle populations. J Biol Chem 1997;272:7085-92.
16. Ploug T, van Deurs B, Ai H, Cushman SW, Ralston E. Analysis of GLUT4 distribution in whole skeletal muscle fibers: identification of distinct storage compartments that are recruited by insulin and muscle contractions. J Cell Biol 1998;142:1429-46.
17. Muller H, Deckers K, Eckel J. The fatty acid translocase (FAT)/CD36 and the glucose transporter GLUT4 are localized in different cellular compartments in rat cardiac muscle. Biochem Biophys Res Commun 2002;293:665-9.
18. Luiken JJFP, Coort SLM, Willems J, Coumans WA, Bonen A, Glatz JFC. Dipyridamole alters cardiac substrate preference by inducing translocation of FAT/CD36, but not that of GLUT4. Mol Pharmacol 2004;65:639-45.
19. Coburn CT, Knapp FF Jr, Febbraio M, Beets AL, Silverstein RL, Abumrad NA. Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J Biol Chem 2000;275:32523-9.
20. Goudriaan JR, Dahlmans VE, Teusink B, Ouwens DM, Febbraio M, Maassen JA, et al. CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice. J Lipid Res 2003;44:2270-7.
21. Abel ED, Kaulbach HC, Tian R, Hopkins JC, Duffy J, Doetschman T, et al. Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. J Clin Invest 1999;104:1703-14.
22. Rosenblatt-Velin N, Montessuit C, Papageorgiou I, Terrand J, Lerch R. Postinfarction heart failure in rats is associated with upregulation of GLUT-1 and downregulation of genes of fatty acid metabolism. Cardiovasc Res 2001;52:407-16.
23. Kadowaki T. Insights into insulin resistance and type 2 diabetes from knockout mouse models. J Clin Invest 2000;106:459-65.
24. Luiken JJFP, Arumugam Y, Dyck DJ, Bell RC, Pelsers MM, Turcotte LP, et al. Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats. J Biol Chem 2001;276:40567-73.
25. Coort SLM, Hasselbaink DM, Koonen DPY, Willems J, Coumans WA, Chabowski A, et al. Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese Zucker rats. Diabetes 2004;53:1655-63.
26. Ouwens DM, Boer C, Fodor M, De Galan P, Heine RJ, Maassen JA, et al. Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats. Diabetologia 2005;48:1229-37.
27. Bonen A, Parolin ML, Steinberg GR, Calles-Escandon J, Tandon NN, Glatz JF, et al. Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36. FASEB J 2004;18:1144-6.
28. Taegtmeyer H. Metabolism - the lost child of cardiology. J Am Coll Cardiol 2000;36:1386-8.
29. Lopaschuk GD, Rebeyka IM, Allard MF. Metabolic modulation: a means to mend a broken heart. Circulation 2002;105:140-2.
30. Stanley WC. Rationale for a metabolic approach in diabetic coronary patients. Coron Artery Dis 2005;16 (Suppl 1):S11-5.