Expressions of neuregulin 1β and ErbB4 in prefrontal cortex and hippocampus of a rat schizophrenia model induced by chronic MK-801 administration

Journal of Biomedicine and Biotechnology

Volumn 2010, Issue , 2010, Pages

  Si, Tian Mei ^a   Feng, Yu ^a   Wang, Xiao Dong ^a,b   Guo, Chun Mei ^a   Yang, Yang ^a   Li, Ji Tao ^a   Su, Yun Ai ^a  

^a PEKING UNIVERSITY   (China)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIZOCILPINE; EPIDERMAL GROWTH FACTOR RECEPTOR 4; NEU DIFFERENTIATION FACTOR; NEUREGULIN 1BETA; UNCLASSIFIED DRUG; DIZOCILPINE MALEATE; EPIDERMAL GROWTH FACTOR RECEPTOR; NEUREGULIN BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; GENE EXPRESSION; GENE LOCATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NEUROPATHOLOGY; NONHUMAN; PREFRONTAL CORTEX; RAT; SCHIZOPHRENIA; TISSUE DISTRIBUTION; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; METABOLISM; WISTAR RAT;

ANIMALIA; RATTUS;

ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DIZOCILPINE MALEATE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NEUREGULIN-1; PREFRONTAL CORTEX; RATS; RATS, WISTAR; RECEPTOR, EPIDERMAL GROWTH FACTOR; SCHIZOPHRENIA;

EID: 77952527708     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2010/859516     Document Type: Article

References (35)

1. Harrison P. J., Owen M. J., Genes for schizophrenia? Recent findings and their pathophysiological implications The Lancet 2003 361 9355 417 419
2. Harrison P. J., Weinberger D. R., Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence Molecular Psychiatry 2005 10 1 40 68
3. Law A. J., Kleinman J. E., Weinberger D. R., Weickert C. S., Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia Human Molecular Genetics 2007 16 2 129 141
4. Norton N., Moskvina V., Morris D. W., Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia American Journal of Medical Genetics Part B 2006 141B 1 96 101
5. Silberberg G., Darvasi A., Pinkas-Kramarski R., Navon R., The involvement of ErbB4 with schizophrenia: association and expression studies American Journal of Medical Genetics Part B 2006 141B 2 142 148
6. Gerlai R., Pisacane P., Erickson S., Heregulin, but not ErbB2 or ErbB3, heterozygous mutant mice exhibit hyperactivity in multiple behavioral tasks Behavioural Brain Research 2000 109 2 219 227
7. Golub M. S., Germann S. L., Lloyd K. C. K., Behavioral characteristics of a nervous system-specific erbB4 knock-out mouse Behavioural Brain Research 2004 153 1 159 170
8. Stefansson H., Sigurdsson E., Steinthorsdottir V., Neuregulin 1 and susceptibility to schizophrenia American Journal of Human Genetics 2002 71 4 877 892
9. Fischbach G. D., Rosen K. M., ARIA: a neuromuscular junction neuregulin Annual Review of Neuroscience 1997 20 429 458
10. Buonanno A., Fischbach G. D., Neuregulin and ErbB receptor signaling pathways in the nervous system Current Opinion in Neurobiology 2001 11 3 287 296
11. Mei L., Xiong W.-C., Neuregulin 1 in neural development, synaptic plasticity and schizophrenia Nature Reviews Neuroscience 2008 9 6 437 452
12. Carpenter G., ErbB-4: mechanism of action and biology Experimental Cell Research 2003 284 1 66 77
13. Lemke G., Glial control of neuronal development Annual Review of Neuroscience 2001 24 87 105
14. Garratt A. N., Britsch S., Birchmeier C., Neuregulin, a factor with many functions in the life of a Schwann cell BioEssays 2000 22 11 987 996
15. Michailov G. V., Sereda M. W., Brinkmann B. G., Axonal neuregulin-1 regulates myelin sheath thickness Science 2004 304 5671 700 703
16. Nave K.-A., Salzer J. L., Axonal regulation of myelination by neuregulin 1 Current Opinion in Neurobiology 2006 16 5 492 500
17. Taveggia C., Zanazzi G., Petrylak A., Neuregulin-1 type III determines the ensheathment fate of axons Neuron 2005 47 5 681 694
18. Arnold S. E., Talbot K., Hahn C.-G., Neurodevelopment, neuroplasticity, and new genes for schizophrenia Progress in Brain Research 2004 147 319 345
19. Esper R. M., Pankonin M. S., Loeb J. A., Neuregulins: versatile growth and differentiation factors in nervous system development and human disease Brain Research Reviews 2006 51 2 161 175
20. Hahn C.-G., Wang H.-Y., Cho D.-S., Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia Nature Medicine 2006 12 7 824 828
21. Chong V. Z., Thompson M., Beltaifa S., Webster M. J., Law A. J., Weickert C. S., Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients Schizophrenia Research 2008 100 13 270 280
22. Rujescu D., Bender A., Keck M., A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities Biological Psychiatry 2006 59 8 721 729
23. Kondziella D., Brenner E., Eyjolfsson E. M., Markinhuhta K. R., Carlsson M. L., Sonnewald U., Glial-neuronal interactions are impaired in the schizophrenia model of repeated MK801 exposure Neuropsychopharmacology 2006 31 9 1880 1887
24. Olney J. W., Farber N. B., Glutamate receptor dysfunction and schizophrenia Archives of General Psychiatry 1995 52 12 998 1007
25. Jentsch J. D., Roth R. H., The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia Neuropsychopharmacology 1999 20 3 201 225
26. Duncan G. E., Miyamoto S., Leipzig J. N., Lieberman J. A., Comparison of brain metabolic activity patterns induced by ketamine, MK-801 and amphetamine in rats: support for NMDA receptor involvement in responses to subanesthetic dose of ketamine Brain Research 1999 843 1-2 171 183
27. Weinberger D. R., Aloia M. S., Goldberg T. E., Berman K. F., The frontal lobes and schizophrenia Journal of Neuropsychiatry and Clinical Neurosciences 1994 6 4 419 427
28. Elvevag B., Goldberg T. E., Cognitive impairment in schizophrenia is the core of the disorder Critical Reviews in Neurobiology 2000 14 1 1 21
29. Eisenberg D. P., Berman K. F., Executive function, neural circuitry, and genetic mechanisms in schizophrenia Neuropsychopharmacology 2010 35 1 258 277
30. Seo M. S., Kim S. H., Ahn Y. M., The effects of repeated administrations of MK-801 on ERK and GSK-3 signalling pathways in the rat frontal cortex International Journal of Neuropsychopharmacology 2007 10 3 359 368
31. Paxinos G., Watson C., The Rat Brain in Stereotaxic Coordinate 2005 San Diego, Calif, USA Academic Press
32. Wang X.-D., Su Y.-A., Guo C.-M., Yang Y., Si T.-M., Chronic antipsychotic drug administration alters the expression of neuregulin 1, ErbB2, ErbB3, and ErbB4 in the rat prefrontal cortex and hippocampus International Journal of Neuropsychopharmacology 2008 11 4 553 561
33. Gearhart D. A., Middlemore M.-L., Terry A. V., ELISA methods to measure cholinergic markers and nerve growth factor receptors in cortex, hippocampus, prefrontal cortex, and basal forebrain from rat brain Journal of Neuroscience Methods 2006 150 2 159 173
34. Garcia R. A. G., Vasudevan K., Buonanno A., The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses Proceedings of the National Academy of Sciences of the United States of America 2000 97 7 3596 3601
35. Huang Y. Z., Won S., Ali D. W., Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses Neuron 2000 26 2 443 455