Surface-induced phase separation of a sphingomyelin/cholesterol/ganglioside GM1-planar bilayer on mica surfaces and microdomain molecular conformation that accelerates Aβ oligomerization

Biochimica et Biophysica Acta - Biomembranes

Volumn 1798, Issue 6, 2010, Pages 1090-1099

  Mao, Yanli ^a,b   Shang, Zhiguo ^c   Imai, Yosuke ^d   Hoshino, Tyuji ^d   Tero, Ryugo ^a,c   Tanaka, Motohiko ^c,e   Yamamoto, Naoki ^f,g   Yanagisawa, Katsuhiko ^g   Urisu, Tsuneo ^a,c  

^a INSTITUTE FOR MOLECULAR SCIENCE   (Japan)

^b HENAN UNIVERSITY   (China)

^c GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^d CHIBA UNIVERSITY   (Japan)

^e NATIONAL INSTITUTE FOR FUSION SCIENCE   (Japan)

^f RITSUMEIKAN UNIVERSITY   (Japan)

^g NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Cholesterol; Ganglioside GM1; Lipid bilayer; Molecular dynamics; Phase separation; Sphingomyelin

Indexed keywords

AMYLOID BETA PROTEIN; CHOLESTEROL; GANGLIOSIDE GM1; MICA; SILICON DIOXIDE; SPHINGOMYELIN;

ARTICLE; CHEMICAL STRUCTURE; LIPID BILAYER; MEMBRANE STRUCTURE; MOLECULAR DYNAMICS; OLIGOMERIZATION; PHASE SEPARATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LIPID INTERACTION; SURFACE PROPERTY;

ALUMINUM SILICATES; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; CATTLE; CHOLESTEROL; COMPUTER SIMULATION; G(M1) GANGLIOSIDE; HUMANS; MEMBRANE MICRODOMAINS; PROTEIN MULTIMERIZATION; SILICON DIOXIDE; SPHINGOMYELINS; SWINE;

EID: 77952510090     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2010.03.003     Document Type: Article

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