A single Phe54Tyr substitution improves the catalytic activity and thermostability of Trigonopsis variabilis d-amino acid oxidase

New Biotechnology

Volumn 27, Issue 1, 2010, Pages 78-84

  Wong, Kin Sing ^a   Fong, Wing Ping ^a   Tsang, Paul Wai Kei ^b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; ANTIBIOTICS; HYDROGEN BONDS; ISOMERS; STABILITY; SUBSTRATES;

CEPHALOSPORIN ANTIBIOTICS; CEPHALOSPORIN C; D-AMINO ACID OXIDASE; HOMOLOGY MODELING; HYDROGEN-BOND FORMATION; INDUSTRIAL PRODUCTION; OXIDATIVE DEAMINATION; TRIGONOPSIS VARIABILIS;

CATALYST ACTIVITY;

7 AMINOCEPHALOSPORANIC ACID; CEPHALOSPORIN C; DEXTRO AMINO ACID OXIDASE; TRIGONOPSIS VARIABILIS DEXTRO AMINO ACID OXIDASE; TYROSINE; UNCLASSIFIED DRUG; 7-AMINOCEPHALOSPORANIC ACID; CEPHALOSPORIN DERIVATIVE; FUNGAL PROTEIN; GLUTARYL 7 AMINOCEPHALOSPORANIC ACID; GLUTARYL-7-AMINOCEPHALOSPORANIC ACID; PHENYLALANINE;

ARTICLE; BIOTRANSFORMATION; COMPUTER MODEL; CRYSTAL STRUCTURE; HYDROGEN BOND; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; THERMOSTABILITY; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME STABILITY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCETALES; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; SYNTHESIS; TEMPERATURE;

TRIGONOPSIS VARIABILIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CATALYSIS; CEPHALOSPORINS; D-AMINO-ACID OXIDASE; ENZYME STABILITY; FUNGAL PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCETALES; SEQUENCE ALIGNMENT; TEMPERATURE; TYROSINE;

EID: 77952507592     PISSN: 18716784     EISSN: 18764347     Source Type: Journal    
DOI: 10.1016/j.nbt.2009.11.002     Document Type: Article

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