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Volumn 24, Issue 5, 2010, Pages 909-917

Comparison of fluoroquinolones: Cytotoxicity on human corneal epithelial cells

Author keywords

Cornea; Cytotoxicity; Fluoroquinolones; MTS; Transepithelial electrical resistance

Indexed keywords

3 (4,5 DIMETHYLTHIAZOL 2 YL) 5 (3 CARBOXYMETHOXYPHENYL) 2 (4 SULFOPHENYL) 2H TETRAZOLIUM; BENZALKONIUM CHLORIDE; CEFAZOLIN; CIPROFLOXACIN; EYE DROPS; GATIFLOXACIN; GENTAMICIN; LEVOFLOXACIN; MOXIFLOXACIN; NORFLOXACIN; OFLOVID; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRAZOLIUM; UNCLASSIFIED DRUG;

EID: 77952499041     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2009.179     Document Type: Article
Times cited : (35)

References (43)
  • 1
    • 1242293649 scopus 로고    scopus 로고
    • Clinical characteristics of microbial keratitis in a university hospital in Taiwan
    • Fong CF, Tseng CH, Hu FR, Wang IJ, Chen WL, Hou YC. Clinical characteristics of microbial keratitis in a university hospital in Taiwan. Am J Ophthalmol 2004;137(2):329-336.
    • (2004) Am. J. Ophthalmol. , vol.137 , Issue.2 , pp. 329-336
    • Fong, C.F.1    Tseng, C.H.2    Hu, F.R.3    Wang, I.J.4    Chen, W.L.5    Hou, Y.C.6
  • 2
    • 0034993474 scopus 로고    scopus 로고
    • Fluoroquinolones: Place in ocular therapy
    • Smith A, Pennefather PM, Kaye SB, Hart CA. Fluoroquinolones: place in ocular therapy. Drugs 2001;61(6):747-761.
    • (2001) Drugs , vol.61 , Issue.6 , pp. 747-761
    • Smith, A.1    Pennefather, P.M.2    Kaye, S.B.3    Hart, C.A.4
  • 3
    • 0033963629 scopus 로고    scopus 로고
    • A review of clinical trials with fluoroquinolones with an emphasis on new agents
    • Blondeau JM. A review of clinical trials with fluoroquinolones with an emphasis on new agents. Expert Opin Investig Drugs 2000;9(2):383-413.
    • (2000) Expert Opin. Investig Drugs , vol.9 , Issue.2 , pp. 383-413
    • Blondeau, J.M.1
  • 4
    • 1542603083 scopus 로고    scopus 로고
    • Fluoroquinolones: Mechanism of action, classification, and development of resistance
    • Blondeau JM. Fluoroquinolones: mechanism of action, classification, and development of resistance. Surv Ophthalmol 2004;49 (Suppl 2):S73-S78.
    • (2004) Surv. Ophthalmol. , vol.49 , Issue.2 SUPPL.
    • Blondeau, J.M.1
  • 5
    • 0031753298 scopus 로고    scopus 로고
    • Fluoroquinolone action against mycobacteria: Effects of C-8 substituents on growth, survival, and resistance
    • Dong Y, Xu C, Zhao X, Domagala J, Drlica K. Fluoroquinolone action against mycobacteria: effects of C-8 substituents on growth, survival, and resistance. Antimicrob Agents Chemother 1998;42(11):2978-2984.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , Issue.11 , pp. 2978-2984
    • Dong, Y.1    Xu, C.2    Zhao, X.3    Domagala, J.4    Drlica, K.5
  • 6
    • 0033511289 scopus 로고    scopus 로고
    • Emerging fluoroquinolone resistance in bacterial keratitis: A 5-year review
    • Goldstein MH, Kowalski RP, Gordon YJ. Emerging fluoroquinolone resistance in bacterial keratitis: a 5-year review. Ophthalmology 1999;106(7):1313-1318.
    • (1999) Ophthalmology , vol.106 , Issue.7 , pp. 1313-1318
    • Goldstein, M.H.1    Kowalski, R.P.2    Gordon, Y.J.3
  • 8
    • 0033777744 scopus 로고    scopus 로고
    • Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones
    • Alexandrakis G, Alfonso EC, Miller D. Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones. Ophthalmology 2000;107(8):1497-1502.
    • (2000) Ophthalmology , vol.107 , Issue.8 , pp. 1497-1502
    • Alexandrakis, G.1    Alfonso, E.C.2    Miller, D.3
  • 9
    • 33646926123 scopus 로고    scopus 로고
    • Recalcitrant post-LASIK Mycobacterium chelonae keratitis eradicated after the use of fourth-generation fluoroquinolone
    • Hamam RN, Noureddin B, Salti HI, Haddad R, Khoury JM. Recalcitrant post-LASIK Mycobacterium chelonae keratitis eradicated after the use of fourth-generation fluoroquinolone. Ophthalmology 2006;113(6):950-954.
    • (2006) Ophthalmology , vol.113 , Issue.6 , pp. 950-954
    • Hamam, R.N.1    Noureddin, B.2    Salti, H.I.3    Haddad, R.4    Khoury, J.M.5
  • 11
    • 30344474254 scopus 로고    scopus 로고
    • Fourth-generation fluoroquinolones in the treatment of mycobacterial infectious keratitis after laser-assisted in situ keratomileusis surgery
    • Lee SB, Oliver KM, Strube YN, Mohan SK, Slomovic AR. Fourth-generation fluoroquinolones in the treatment of mycobacterial infectious keratitis after laser-assisted in situ keratomileusis surgery. Can J Ophthalmol 2005;40(6):750-753.
    • (2005) Can J. Ophthalmol. , vol.40 , Issue.6 , pp. 750-753
    • Lee, S.B.1    Oliver, K.M.2    Strube, Y.N.3    Mohan, S.K.4    Slomovic, A.R.5
  • 12
    • 33646475165 scopus 로고    scopus 로고
    • Fourthgeneration fluoroquinolone-resistant bacterial keratitis after refractive surgery
    • Moshirfar M, Mirzaian G, Feiz V, Kang PC. Fourthgeneration fluoroquinolone-resistant bacterial keratitis after refractive surgery. J Cataract Refract Surg 2006;32(3):515-518.
    • (2006) J. Cataract Refract. Surg. , vol.32 , Issue.3 , pp. 515-518
    • Moshirfar, M.1    Mirzaian, G.2    Feiz, V.3    Kang, P.C.4
  • 13
    • 33947601439 scopus 로고    scopus 로고
    • Endophthalmitis after uncomplicated cataract surgery with the use of fourth-generation fluoroquinolones: A retrospective observational case series
    • Moshirfar M, Feiz V, Vitale AT, Wegelin JA, Basavanthappa S, Wolsey DH. Endophthalmitis after uncomplicated cataract surgery with the use of fourth-generation fluoroquinolones: a retrospective observational case series. Ophthalmology 2007;114(4):686-691.
    • (2007) Ophthalmology , vol.114 , Issue.4 , pp. 686-691
    • Moshirfar, M.1    Feiz, V.2    Vitale, A.T.3    Wegelin, J.A.4    Basavanthappa, S.5    Wolsey, D.H.6
  • 15
    • 34548239710 scopus 로고    scopus 로고
    • Clinical efficacy of moxifloxacin in the treatment of bacterial keratitis: A randomized clinical trial
    • Constantinou M, Daniell M, Snibson GR, Vu HT, Taylor HR. Clinical efficacy of moxifloxacin in the treatment of bacterial keratitis: a randomized clinical trial. Ophthalmology 2007;114(9):1622-1629.
    • (2007) Ophthalmology , vol.114 , Issue.9 , pp. 1622-1629
    • Constantinou, M.1    Daniell, M.2    Snibson, G.R.3    Vu, H.T.4    Taylor, H.R.5
  • 17
    • 14144249163 scopus 로고    scopus 로고
    • Comparative efficacy of topical moxifloxacin versus ciprofloxacin and vancomycin in the treatment of Paeruginosa and ciprofloxacin-resistant MRSA keratitis in rabbits
    • Aliprandis E, Ciralsky J, Lai H, Herling I, Katz HR. Comparative efficacy of topical moxifloxacin versus ciprofloxacin and vancomycin in the treatment of Paeruginosa and ciprofloxacin-resistant MRSA keratitis in rabbits. Cornea 2005;24(2):201-205.
    • (2005) Cornea , vol.24 , Issue.2 , pp. 201-205
    • Aliprandis, E.1    Ciralsky, J.2    Lai, H.3    Herling, I.4    Katz, H.R.5
  • 18
    • 14044278165 scopus 로고    scopus 로고
    • Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits
    • Jensen H, Zerouala C, Carrier M, Short B. Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits. J Ocul Pharmacol Ther 2005;21(1):36-43.
    • (2005) J. Ocul Pharmacol. Ther. , vol.21 , Issue.1 , pp. 36-43
    • Jensen, H.1    Zerouala, C.2    Carrier, M.3    Short, B.4
  • 19
    • 34447519029 scopus 로고    scopus 로고
    • Comparison of antibiotic effect and corneal epithelial toxicity of levofloxacin and moxifloxacin in vitro
    • Kim SY, Lim JA, Choi JS, Choi EC, Joo CK. Comparison of antibiotic effect and corneal epithelial toxicity of levofloxacin and moxifloxacin in vitro. Cornea 2007;26(6):720-725.
    • (2007) Cornea , vol.26 , Issue.6 , pp. 720-725
    • Kim, S.Y.1    Lim, J.A.2    Choi, J.S.3    Choi, E.C.4    Joo, C.K.5
  • 20
    • 0042828942 scopus 로고    scopus 로고
    • Gatifloxacin and moxifloxacin: An in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates
    • Kowalski RP, Dhaliwal DK, Karenchak LM, Romanowski EG, Mah FS, Ritterband DC et al Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates. Am J Ophthalmol 2003;136(3):500-505.
    • (2003) Am. J. Ophthalmol. , vol.136 , Issue.3 , pp. 500-505
    • Kowalski, R.P.1    Dhaliwal, D.K.2    Karenchak, L.M.3    Romanowski, E.G.4    Mah, F.S.5    Ritterband, D.C.6
  • 21
    • 22444449079 scopus 로고    scopus 로고
    • The effect of fourthgeneration fluoroquinolones gatifloxacin and moxifloxacin on epithelial healing following photorefractive keratectomy
    • Burka JM, Bower KS, Vanroekel RC, Stutzman RD, Kuzmowych CP, Howard RS. The effect of fourthgeneration fluoroquinolones gatifloxacin and moxifloxacin on epithelial healing following photorefractive keratectomy. Am J Ophthalmol 2005;140(1):83-87.
    • (2005) Am. J. Ophthalmol. , vol.140 , Issue.1 , pp. 83-87
    • Burka, J.M.1    Bower, K.S.2    Vanroekel, R.C.3    Stutzman, R.D.4    Kuzmowych, C.P.5    Howard, R.S.6
  • 22
    • 3242809854 scopus 로고    scopus 로고
    • Evaluation of the corneal effects of topical ophthalmic fluoroquinolones using in vivo confocal microscopy
    • Kovoor TA, Kim AS, McCulley JP, Cavanagh HD, Jester JV, Bugde AC et al Evaluation of the corneal effects of topical ophthalmic fluoroquinolones using in vivo confocal microscopy. Eye Contact Lens 2004;30(2):90-94.
    • (2004) Eye Contact Lens , vol.30 , Issue.2 , pp. 90-94
    • Kovoor, T.A.1    Kim, A.S.2    McCulley, J.P.3    Cavanagh, H.D.4    Jester, J.V.5    Bugde, A.C.6
  • 23
    • 33748452124 scopus 로고    scopus 로고
    • Confocal assessment of the effects of fourth-generation fluoroquinolones on the cornea
    • Ly LT, Cavanagh HD, Petroll WM. Confocal assessment of the effects of fourth-generation fluoroquinolones on the cornea. Eye Contact Lens 2006;32(4):161-165.
    • (2006) Eye Contact Lens , vol.32 , Issue.4 , pp. 161-165
    • Ly, L.T.1    Cavanagh, H.D.2    Petroll, W.M.3
  • 24
    • 36749009182 scopus 로고    scopus 로고
    • Corneal wound healing in New Zealand white rabbits following anterior keratectomy and treatment with moxifloxacin ophthalmic solution 0.5% or gatifloxacin ophthalmic solution 0.3%
    • Williams KK, Shepard AR, Rice RL, McCartney MD, Wax MB, Hiddemen JW. Corneal wound healing in New Zealand white rabbits following anterior keratectomy and treatment with moxifloxacin ophthalmic solution 0.5% or gatifloxacin ophthalmic solution 0.3%. J Ocul Pharmacol Ther 2007;23(6):517-525.
    • (2007) J. Ocul Pharmacol. Ther. , vol.23 , Issue.6 , pp. 517-525
    • Williams, K.K.1    Shepard, A.R.2    Rice, R.L.3    McCartney, M.D.4    Wax, M.B.5    Hiddemen, J.W.6
  • 25
    • 34547404228 scopus 로고    scopus 로고
    • Effect of fourth-generation fluoroquinolones on the healing rate of corneal erosions in an animal model
    • Barequet IS, Habot-Wilner Z, Lavinsky F, Ziv H, Belkin M, Rosner M. Effect of fourth-generation fluoroquinolones on the healing rate of corneal erosions in an animal model. Cornea 2007;26(5):606-609.
    • (2007) Cornea , vol.26 , Issue.5 , pp. 606-609
    • Barequet, I.S.1    Habot-Wilner, Z.2    Lavinsky, F.3    Ziv, H.4    Belkin, M.5    Rosner, M.6
  • 26
    • 11144222541 scopus 로고    scopus 로고
    • Comparison of corneal surface effects of gatifloxacin and moxifloxacin using intensive and prolonged dosing protocols
    • Herrygers LA, Noecker RJ, Lane LC, Levine JM. Comparison of corneal surface effects of gatifloxacin and moxifloxacin using intensive and prolonged dosing protocols. Cornea 2005;24(1):66-71.
    • (2005) Cornea , vol.24 , Issue.1 , pp. 66-71
    • Herrygers, L.A.1    Noecker, R.J.2    Lane, L.C.3    Levine, J.M.4
  • 27
    • 27844583146 scopus 로고    scopus 로고
    • Safety of moxifloxacin as shown in animal and in vitro studies
    • McGee DH, Holt WF, Kastner PR, Rice RL. Safety of moxifloxacin as shown in animal and in vitro studies. Surv Ophthalmol 2005;50 (Suppl 1):S46-S54.
    • (2005) Surv Ophthalmol. , vol.50 , Issue.1 SUPPL.
    • McGee, D.H.1    Holt, W.F.2    Kastner, P.R.3    Rice, R.L.4
  • 28
    • 33750441168 scopus 로고    scopus 로고
    • Severe corneal toxicity after topical fluoroquinolone therapy: Report of two cases
    • Walter K, Tyler ME. Severe corneal toxicity after topical fluoroquinolone therapy: report of two cases. Cornea 2006;25(7):855-857.
    • (2006) Cornea , vol.25 , Issue.7 , pp. 855-857
    • Walter, K.1    Tyler, M.E.2
  • 29
    • 1842607593 scopus 로고    scopus 로고
    • The effect of the corneal epithelium on the intraocular penetration of fluoroquinolone ophthalmic solution
    • Fukuda M, Inoue A, Sasaki K, Takahashi N. The effect of the corneal epithelium on the intraocular penetration of fluoroquinolone ophthalmic solution. Jpn J Ophthalmol 2004;48(2):93-96.
    • (2004) Jpn. J. Ophthalmol. , vol.48 , Issue.2 , pp. 93-96
    • Fukuda, M.1    Inoue, A.2    Sasaki, K.3    Takahashi, N.4
  • 30
    • 2442585595 scopus 로고    scopus 로고
    • Corneal epithelial cellular dysfunction from benzalkonium chloride (BAC) in vitro
    • Cha SH, Lee JS, Oum BS, Kim CD. Corneal epithelial cellular dysfunction from benzalkonium chloride (BAC) in vitro. Clin Experiment Ophthalmol 2004;32(2):180-184.
    • (2004) Clin. Experiment Ophthalmol. , vol.32 , Issue.2 , pp. 180-184
    • Cha, S.H.1    Lee, J.S.2    Oum, B.S.3    Kim, C.D.4
  • 31
    • 33746765813 scopus 로고    scopus 로고
    • Fluoroquinolone eye drop-induced cytotoxicity: Role of preservative in P2X7 cell death receptor activation and apoptosis
    • Dutot M, Pouzaud F, Larosche I, Brignole-Baudouin F, Warnet JM, Rat P. Fluoroquinolone eye drop-induced cytotoxicity: role of preservative in P2X7 cell death receptor activation and apoptosis. Invest Ophthalmol Vis Sci 2006;47(7):2812-2819.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , Issue.7 , pp. 2812-2819
    • Dutot, M.1    Pouzaud, F.2    Larosche, I.3    Brignole-Baudouin, F.4    Warnet, J.M.5    Rat, P.6
  • 32
    • 2442743988 scopus 로고    scopus 로고
    • ZO1 in corneal epithelium: Association to the zonula occludens and adherens junctions
    • Sugrue SP, Zieske JD. ZO1 in corneal epithelium: association to the zonula occludens and adherens junctions. Exp Eye Res 1997;64(1):11-20.
    • (1997) Exp. Eye Res. , vol.64 , Issue.1 , pp. 11-20
    • Sugrue, S.P.1    Zieske, J.D.2
  • 33
    • 0033653266 scopus 로고    scopus 로고
    • Corneal epithelial tight junctions and their response to lipopolysaccharide challenge
    • Yi X, Wang Y, Yu FS. Corneal epithelial tight junctions and their response to lipopolysaccharide challenge. Invest Ophthalmol Vis Sci 2000;41(13):4093-4100.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , Issue.13 , pp. 4093-4100
    • Yi, X.1    Wang, Y.2    Yu, F.S.3
  • 35
    • 0037974683 scopus 로고    scopus 로고
    • In vitro toxicity of netilmicin and ofloxacin on corneal epithelial cells
    • Scuderi AC, Paladino GM, Marino C, Trombetta F. In vitro toxicity of netilmicin and ofloxacin on corneal epithelial cells. Cornea 2003;22(5):468-472.
    • (2003) Cornea , vol.22 , Issue.5 , pp. 468-472
    • Scuderi, A.C.1    Paladino, G.M.2    Marino, C.3    Trombetta, F.4
  • 36
    • 23044436765 scopus 로고    scopus 로고
    • In vivo toxicity of netilmicin and ofloxacin on intact and mechanically damaged eyes of rabbit
    • Marino C, Paladino GM, Scuderi AC, Trombetta F, Mugridge K, Enea V. In vivo toxicity of netilmicin and ofloxacin on intact and mechanically damaged eyes of rabbit. Cornea 2005;24(6):710-716.
    • (2005) Cornea , vol.24 , Issue.6 , pp. 710-716
    • Marino, C.1    Paladino, G.M.2    Scuderi, A.C.3    Trombetta, F.4    Mugridge, K.5    Enea, V.6
  • 37
    • 29744459845 scopus 로고    scopus 로고
    • In vitro effects of fluoroquinolone and aminoglycoside antibiotics on human keratocytes
    • Leonardi A, Papa V, Fregona I, Russo P, De Franchis G, Milazzo G. In vitro effects of fluoroquinolone and aminoglycoside antibiotics on human keratocytes. Cornea 2006;25(1):85-90.
    • (2006) Cornea , vol.25 , Issue.1 , pp. 85-90
    • Leonardi, A.1    Papa, V.2    Fregona, I.3    Russo, P.4    De Franchis, G.5    Milazzo, G.6
  • 38
    • 0035167367 scopus 로고    scopus 로고
    • Increased incidence of corneal perforation after topical fluoroquinolone treatment for microbial keratitis
    • Mallari PL, McCarty DJ, Daniell M, Taylor H. Increased incidence of corneal perforation after topical fluoroquinolone treatment for microbial keratitis. Am J Ophthalmol 2001;131(1):131-133.
    • (2001) Am. J. Ophthalmol. , vol.131 , Issue.1 , pp. 131-133
    • Mallari, P.L.1    McCarty, D.J.2    Daniell, M.3    Taylor, H.4
  • 39
    • 0345304332 scopus 로고    scopus 로고
    • Corneal ciprofloxacin precipitation during bacterial keratitis
    • Wilhelmus KR, Abshire RL. Corneal ciprofloxacin precipitation during bacterial keratitis. Am J Ophthalmol 2003;136(6):1032-1037.
    • (2003) Am. J. Ophthalmol. , vol.136 , Issue.6 , pp. 1032-1037
    • Wilhelmus, K.R.1    Abshire, R.L.2
  • 40
    • 0034750082 scopus 로고    scopus 로고
    • Ciprofloxacin microprecipitates and macroprecipitates in the human corneal epithelium
    • Eiferman RA, Snyder JP, Nordquist RE. Ciprofloxacin microprecipitates and macroprecipitates in the human corneal epithelium. J Cataract Refract Surg 2001;27(10):1701-1702.
    • (2001) J. Cataract Refract. Surg. , vol.27 , Issue.10 , pp. 1701-1702
    • Eiferman, R.A.1    Snyder, J.P.2    Nordquist, R.E.3
  • 41
    • 0032007027 scopus 로고    scopus 로고
    • Corneal ulcer associated with deposits of norfloxacin
    • Konishi M, Yamada M, Mashima Y. Corneal ulcer associated with deposits of norfloxacin. Am J Ophthalmol 1998;125(2):258-260.
    • (1998) Am. J. Ophthalmol. , vol.125 , Issue.2 , pp. 258-260
    • Konishi, M.1    Yamada, M.2    Mashima, Y.3
  • 42
    • 33845463794 scopus 로고    scopus 로고
    • Comparative toxicity of fluoroquinolone antibiotics on corneal cells in vitro
    • Matsumoto S, Way W, Tarlo K, Short B. Comparative toxicity of fluoroquinolone antibiotics on corneal cells in vitro. Cornea 2006;25 (2):S1-S7.
    • (2006) Cornea , vol.25 , Issue.2
    • Matsumoto, S.1    Way, W.2    Tarlo, K.3    Short, B.4
  • 43
    • 0031687944 scopus 로고    scopus 로고
    • Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line
    • Saarinen-Savolainen P, Jarvinen T, Araki-Sasaki K, Watanabe H, Urtti A. Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line. Pharm Res 1998;15(8):1275-1280.
    • (1998) Pharm. Res. , vol.15 , Issue.8 , pp. 1275-1280
    • Saarinen-Savolainen, P.1    Jarvinen, T.2    Araki-Sasaki, K.3    Watanabe, H.4    Urtti, A.5


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