Effect of fourth-generation fluoroquinolones on the healing rate of corneal erosions in an animal model

Cornea

Volumn 26, Issue 5, 2007, Pages 606-609

  Barequet, Irina S ^a,b   Habot Wilner, Zohar ^a   Lavinsky, Fabio ^a   Ziv, Hana ^a   Belkin, Michael ^a   Rosner, Mordechai ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

Author keywords

Corneal erosion; Fluoroquinolones; Fourth generation fluoroquinolones; Gatifloxacin; Moxifloxacin; Prophylaxis in corneal erosions

Indexed keywords

GATIFLOXACIN; MOXIFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA EROSION; DRUG EFFECT; DRUG EFFICACY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RANDOMIZATION; STATISTICAL SIGNIFICANCE; TISSUE REPAIR;

ANIMALS; ANTI-INFECTIVE AGENTS; AZA COMPOUNDS; CORNEAL DISEASES; DISEASE MODELS, ANIMAL; EPITHELIUM, CORNEAL; FLUOROQUINOLONES; MALE; QUINOLINES; RABBITS; WOUND HEALING;

EID: 34547404228     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICO.0b013e318041f08e     Document Type: Article

References (20)

1. Donnenfeld ED, O'Brien TP, Solomon R, et al. Infectious keratitis after photorefractive keratectomy. Ophthalmology. 2003;110:743-747.
2. Förster W, Becker K, Hungermann D, et al. Methicillin resistant Staphylococcus aureus keratitis after excimer laser photorefractive keratectomy. J Cataract Refract Surg. 2002;28:722-724.
3. Mather R, Karenchak LM, Romanowski EQ, et al. Fourth-generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics. Am J Ophthalmol. 2003;133:463-466.
4. Burka JM, Bower KS, Vanroekel RC, et al. The effect of fourth-generation fluoroquinolones gatifloxacin and moxifloxacin on epithelial healing following photorefractive keratectomy. Am J Ophthalmol. 2005;140:83-87.
5. Durrie DS, Trattler W. A comparison of therapeutic regimens containing moxifloxacin 0.5% ophthalmic solution and gatifloxacin 0.3% ophthalmic solution for surgical prophylaxis in patients undergoing LASIK or LASEK. J Ocul Pharmacol Ther. 2005;21:236-241.
6. Moshirfar M, Marx DP, Kumar R. The effect of the fourth-generation fluoroquinolones on corneal reepithelialization after penetrating keratoplasty. Cornea. 2005;24:833-836.
7. Goldstein MH, Kowalski RP, Gordon YJ. Emerging fluoroquinolones resistance in bacterial keratitis. Ophthalmology. 1999;106:1313-1318.
8. Hwang DG. Fluoroquinolone resistance in ophthalmology and the potential role for newer ophthalmic fluoroquinolones. Surv Ophthalmol. 2004;49:S79-S83.
9. Kowalski RP, Dhaliwal DK, Karenchak LM, et al. Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates. Am J Ophthalmol. 2003;136:500-505.
10. Callegan MC, Ramirez R, Kane ST, et al. Antibacterial activity of the fourth-generation fluoroquinolones gatifloxacin and moxifloxacin against ocular pathogens. Adv Ther. 2003;20:246-252.
11. Mather R, Karenchak LM, Romanowski EG, et al. Fourth generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics. Am J Ophthalmol. 2002;133:463-466.
12. Sarayba MA, Shamie N, Reiser BJ, et al. Fluoroquinolone therapy in Mycobacterium chelonae keratitis after lamellar keratectomy. J Cataract Refract Surg. 2005;31:1396-1402.
13. Romanowski EG, Mah FS, Yates KA, et al. The successful treatment of gatifloxacin-resistant Staphylococcus aureus keratitis with Zymar (gatifloxacin 0.3%) in a NZW rabbit model. Am J Ophthalmol. 2005;139:867-877.
14. McGee DH, Holt WF, Kastner PR, et al. Safety of moxifloxacin as shown in animal and in vitro studies. Surv Ophthalmol. 2005;50:S46-S54.
15. Kossendrup D, Wiederholt M, Hoffmann F. Influence of cyclosporine A, dexamethasone, and benzalkonium chloride (BAK) on corneal epithelial wound healing in the rabbit and guinea pig eye. Cornea. 1985;86:177-181.
16. Lazarus HM, Imperia PS, Botti RE, et al. An in vitro method which assesses corneal epithelial toxicity due to antineoplastic, preservative and antimicrobial agents. Lens Eye Toxic Res. 1989;6:59-85.
17. Collin HB, Grabsch BE. The effect of ophthalmic preservatives on the healing rate of the rabbit corneal epithelium after keratectomy. Am J Optom Physiol Opt. 1982;59:215-222.
18. Herrygers LA, Noecker RJ, Lane LC, et al. Comparison of corneal surface effects of gatifloxacin and moxifloxacin using intensive and prolonged dosing protocols. Cornea. 2005;24:66-71.
19. Price MO, Price FW Jr, Maclellan D. Effect of gatifloxacin 0.3% and moxifloxacin 0.5% ophthalmic solutions on human corneal epithelium following 2 dosing regimens. J Cataract Refract Surg. 2005;31:2137-2141.
20. Ly LT, Cavanagh HD, Petroll WM. Confocal assessment of the effects of fourth-generation fluoroquinolones on the cornea. Eye Contact Lens. 2006;32:161-165.