Initial insights regarding the role of p53 in maintaining sperm DNA integrity following treatment of mice with ethylnitrosourea or cyclophosphamide

Toxicologic Pathology

Volumn 38, Issue 2, 2010, Pages 244-257

  Sue Marty, M ^a   Singh, Narendra P ^b   Stebbins, Kenneth E ^a   Ann Linscombe, V ^a   Passage, Julie ^a   Gollapudi, B Bhaskar ^a  

^a DOW CHEMICAL COMPANY   (United States)

^b University of Washington   (United States)

Author keywords

Apoptosis; DNA repair; DNA strand breaks; Mutagen; P53; Spermatogenesis

Indexed keywords

CYCLOPHOSPHAMIDE; ETHYLNITROSOUREA; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; GENOTYPE; HISTOPATHOLOGY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; SPERMATID; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MATURATION; TESTIS; WILD TYPE; ZYGOSITY;

ALKYLATING AGENTS; ANIMALS; COMET ASSAY; CYCLOPHOSPHAMIDE; DNA; DNA DAMAGE; DNA REPAIR; ETHYLNITROSOUREA; MALE; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; SPERMATOZOA; TESTIS; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 77952478226     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623309357947     Document Type: Article

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