메뉴 건너뛰기




Volumn 52, Issue 6, 2010, Pages 937-938

A new life for bile acids

Author keywords

Bile acids; Bile acid specific G protein coupled receptor TGR5; Farnesoid X receptor

Indexed keywords

6ALPHA ETHYL 23 METHYLCHOLIC ACID; BILE ACID; CELL NUCLEUS RECEPTOR; CHENODEOXYCHOLIC ACID; CHOLIC ACID; CHOLIC ACID DERIVATIVE; DEOXYCHOLIC ACID; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1; LITHOCHOLIC ACID; PROTEIN FXR; PROTEIN TGR5; TAUROLITHOCHOLIC ACID; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

EID: 77952420805     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.02.003     Document Type: Note
Times cited : (15)

References (29)
  • 1
    • 0019797502 scopus 로고
    • Interaction of the chick oviduct progesterone receptor with deoxyribonucleic acid
    • Hughes M.R., Compton J.G., Schrader W.T., and O'Malley B.W. Interaction of the chick oviduct progesterone receptor with deoxyribonucleic acid. Biochemistry 20 (1981) 2481-2491
    • (1981) Biochemistry , vol.20 , pp. 2481-2491
    • Hughes, M.R.1    Compton, J.G.2    Schrader, W.T.3    O'Malley, B.W.4
  • 2
    • 0023134513 scopus 로고
    • Molecular cloning of complementary DNA encoding the avian receptor for vitamin D
    • McDonnell D.P., Mangelsdorf D.J., Pike J.W., Haussler M.R., and O'Malley B.W. Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. Science 235 (1987) 1214-1217
    • (1987) Science , vol.235 , pp. 1214-1217
    • McDonnell, D.P.1    Mangelsdorf, D.J.2    Pike, J.W.3    Haussler, M.R.4    O'Malley, B.W.5
  • 3
    • 0023221667 scopus 로고
    • Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor
    • Arriza J.L., Weinberger C., Cerelli G., et al. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science 237 (1987) 268-275
    • (1987) Science , vol.237 , pp. 268-275
    • Arriza, J.L.1    Weinberger, C.2    Cerelli, G.3
  • 4
    • 0023227169 scopus 로고
    • Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system
    • Thompson C.C., Weinberger C., Lebo R., and Evans R.M. Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. Science 237 (1987) 1610-1614
    • (1987) Science , vol.237 , pp. 1610-1614
    • Thompson, C.C.1    Weinberger, C.2    Lebo, R.3    Evans, R.M.4
  • 5
    • 0020080496 scopus 로고
    • Chicken oviduct progesterone receptor: location of specific regions of high-affinity binding in cloned DNA fragments of hormone-responsive genes
    • Mulvihill E.R., LePennec J.P., and Chambon P. Chicken oviduct progesterone receptor: location of specific regions of high-affinity binding in cloned DNA fragments of hormone-responsive genes. Cell 28 (1982) 621-632
    • (1982) Cell , vol.28 , pp. 621-632
    • Mulvihill, E.R.1    LePennec, J.P.2    Chambon, P.3
  • 6
    • 0016843818 scopus 로고
    • The metabolic code
    • Tomkins G.M. The metabolic code. Science 189 (1975) 760-763
    • (1975) Science , vol.189 , pp. 760-763
    • Tomkins, G.M.1
  • 7
    • 0029046931 scopus 로고
    • Identification of a nuclear receptor that is activated by farnesol metabolites
    • Forman B.M., Goode E., Chen J., et al. Identification of a nuclear receptor that is activated by farnesol metabolites. Cell 81 (1995) 687-693
    • (1995) Cell , vol.81 , pp. 687-693
    • Forman, B.M.1    Goode, E.2    Chen, J.3
  • 8
    • 0033591297 scopus 로고    scopus 로고
    • Identification of a nuclear receptor for bile acids
    • Makishima M., Okamoto A.Y., Repa J.J., et al. Identification of a nuclear receptor for bile acids. Science 284 (1999) 1362-1365
    • (1999) Science , vol.284 , pp. 1362-1365
    • Makishima, M.1    Okamoto, A.Y.2    Repa, J.J.3
  • 9
    • 0033591387 scopus 로고    scopus 로고
    • Bile acids: natural ligands for an orphan nuclear receptor
    • Parks D.J., Blanchard S.G., Bledsoe R.K., et al. Bile acids: natural ligands for an orphan nuclear receptor. Science 284 (1999) 1365-1368
    • (1999) Science , vol.284 , pp. 1365-1368
    • Parks, D.J.1    Blanchard, S.G.2    Bledsoe, R.K.3
  • 10
    • 33645509321 scopus 로고    scopus 로고
    • Farnesoid X receptor is essential for normal glucose homeostasis
    • Ma K., Saha P.K., Chan L., and Moore D.D. Farnesoid X receptor is essential for normal glucose homeostasis. J Clin Invest 116 (2006) 1102-1109
    • (2006) J Clin Invest , vol.116 , pp. 1102-1109
    • Ma, K.1    Saha, P.K.2    Chan, L.3    Moore, D.D.4
  • 11
    • 85047694456 scopus 로고    scopus 로고
    • Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
    • Watanabe M., Houten S.M., Wang L., et al. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J Clin Invest 113 (2004) 1408-1418
    • (2004) J Clin Invest , vol.113 , pp. 1408-1418
    • Watanabe, M.1    Houten, S.M.2    Wang, L.3
  • 12
    • 32244447570 scopus 로고    scopus 로고
    • Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice
    • Zhang Y., Lee F.Y., Barrera G., et al. Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. Proc Natl Acad Sci USA 103 (2006) 1006-1011
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 1006-1011
    • Zhang, Y.1    Lee, F.Y.2    Barrera, G.3
  • 13
    • 33645531297 scopus 로고    scopus 로고
    • The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice
    • Cariou B., van H.K., Duran-Sandoval D., et al. The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice. J Biol Chem 281 (2006) 11039-11049
    • (2006) J Biol Chem , vol.281 , pp. 11039-11049
    • Cariou, B.1    van, H.K.2    Duran-Sandoval, D.3
  • 14
    • 56149085041 scopus 로고    scopus 로고
    • Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response
    • Wang Y.D., Chen W.D., Wang M., Yu D., Forman B.M., and Huang W. Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response. Hepatology 48 (2008) 1632-1643
    • (2008) Hepatology , vol.48 , pp. 1632-1643
    • Wang, Y.D.1    Chen, W.D.2    Wang, M.3    Yu, D.4    Forman, B.M.5    Huang, W.6
  • 15
    • 38849164313 scopus 로고    scopus 로고
    • FXR-mediated regulation of eNOS expression in vascular endothelial cells
    • Li J., Wilson A., Kuruba R., et al. FXR-mediated regulation of eNOS expression in vascular endothelial cells. Cardiovasc Res 77 (2008) 169-177
    • (2008) Cardiovasc Res , vol.77 , pp. 169-177
    • Li, J.1    Wilson, A.2    Kuruba, R.3
  • 16
    • 22944449688 scopus 로고    scopus 로고
    • A farnesoid x receptor-small heterodimer partner regulatory cascade modulates tissue metalloproteinase inhibitor-1 and matrix metalloprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis
    • Fiorucci S., Rizzo G., Antonelli E., et al. A farnesoid x receptor-small heterodimer partner regulatory cascade modulates tissue metalloproteinase inhibitor-1 and matrix metalloprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis. J Pharmacol Exp Ther 314 (2005) 584-595
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 584-595
    • Fiorucci, S.1    Rizzo, G.2    Antonelli, E.3
  • 17
    • 0035853165 scopus 로고    scopus 로고
    • The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
    • Staudinger J.L., Goodwin B., Jones S.A., et al. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci USA 98 (2001) 3369-3374
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3369-3374
    • Staudinger, J.L.1    Goodwin, B.2    Jones, S.A.3
  • 18
    • 0037123667 scopus 로고    scopus 로고
    • Vitamin D receptor as an intestinal bile acid sensor
    • Makishima M., Lu T.T., Xie W., et al. Vitamin D receptor as an intestinal bile acid sensor. Science 296 (2002) 1313-1316
    • (2002) Science , vol.296 , pp. 1313-1316
    • Makishima, M.1    Lu, T.T.2    Xie, W.3
  • 19
    • 59149090185 scopus 로고    scopus 로고
    • Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor
    • Kohle C., and Bock K.W. Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor. Biochem Pharmacol 77 (2009) 689-699
    • (2009) Biochem Pharmacol , vol.77 , pp. 689-699
    • Kohle, C.1    Bock, K.W.2
  • 20
    • 33646871585 scopus 로고    scopus 로고
    • Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents
    • Boyer J.L., Trauner M., Mennone A., et al. Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents. Am J Physiol Gastrointest Liver Physiol 290 (2006) G1124-G1130
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Boyer, J.L.1    Trauner, M.2    Mennone, A.3
  • 22
    • 0037024360 scopus 로고    scopus 로고
    • Identification of G protein-coupled receptor genes from the human genome sequence
    • Takeda S., Kadowaki S., Haga T., Takaesu H., and Mitaku S. Identification of G protein-coupled receptor genes from the human genome sequence. FEBS Lett 520 (2002) 97-101
    • (2002) FEBS Lett , vol.520 , pp. 97-101
    • Takeda, S.1    Kadowaki, S.2    Haga, T.3    Takaesu, H.4    Mitaku, S.5
  • 23
    • 0036432845 scopus 로고    scopus 로고
    • Identification of membrane-type receptor for bile acids (M-BAR)
    • Maruyama T., Miyamoto Y., Nakamura T., et al. Identification of membrane-type receptor for bile acids (M-BAR). Biochem Biophys Res Commun 298 (2002) 714-719
    • (2002) Biochem Biophys Res Commun , vol.298 , pp. 714-719
    • Maruyama, T.1    Miyamoto, Y.2    Nakamura, T.3
  • 24
    • 0003269455 scopus 로고    scopus 로고
    • A G protein-coupled receptor responsive to bile acids
    • Kawamata Y., Fujii R., Hosoya M., et al. A G protein-coupled receptor responsive to bile acids. J Biol Chem 278 (2003) 9435-9440
    • (2003) J Biol Chem , vol.278 , pp. 9435-9440
    • Kawamata, Y.1    Fujii, R.2    Hosoya, M.3
  • 25
    • 31444454037 scopus 로고    scopus 로고
    • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
    • Watanabe M., Houten S.M., Mataki C., et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 439 (2006) 484-489
    • (2006) Nature , vol.439 , pp. 484-489
    • Watanabe, M.1    Houten, S.M.2    Mataki, C.3
  • 26
    • 69149083245 scopus 로고    scopus 로고
    • TGR5-mediated bile acid sensing controls glucose homeostasis
    • Thomas C., Gioiello A., Noriega L., et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab 10 (2009) 167-177
    • (2009) Cell Metab , vol.10 , pp. 167-177
    • Thomas, C.1    Gioiello, A.2    Noriega, L.3
  • 27
    • 73249142867 scopus 로고    scopus 로고
    • Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity
    • Pellicciari R., Gioiello A., Macchiarulo A., et al. Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity. J Med Chem 52 (2009) 7958-7961
    • (2009) J Med Chem , vol.52 , pp. 7958-7961
    • Pellicciari, R.1    Gioiello, A.2    Macchiarulo, A.3
  • 28
    • 69749127975 scopus 로고    scopus 로고
    • Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism
    • Patti M.E., Houten S.M., Bianco A.C., et al. Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity (Silver Spring) 17 (2009) 1671-1677
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1671-1677
    • Patti, M.E.1    Houten, S.M.2    Bianco, A.C.3
  • 29
    • 65449177586 scopus 로고    scopus 로고
    • High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis
    • Schaap F.G., van der Gaag N.A., Gouma D.J., and Jansen P.L. High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis. Hepatology 49 (2009) 1228-1235
    • (2009) Hepatology , vol.49 , pp. 1228-1235
    • Schaap, F.G.1    van der Gaag, N.A.2    Gouma, D.J.3    Jansen, P.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.