Genetics of complex disorders

Biochemical and Biophysical Research Communications

Volumn 396, Issue 1, 2010, Pages 143-146

  Kere, Juha ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Gene mapping; Genome wide association study; Linkage disequilibrium

Indexed keywords

ANALYTIC METHOD; ARTICLE; CHROMOSOME MARKER; DNA MICROARRAY; DNA SEQUENCE; ENVIRONMENTAL FACTOR; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC LINKAGE; HUMAN; HUMAN GENOME; INHERITANCE; MEDICAL RESEARCH; MOLECULAR CLONING; MOLECULAR GENETICS; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTHERN BLOTTING;

CHROMOSOMES, HUMAN; CLONING, MOLECULAR; GENETIC DISEASES, INBORN; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETICS, MEDICAL; GENOME-WIDE ASSOCIATION STUDY; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; LINKAGE (GENETICS);

EID: 77952405802     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.04.013     Document Type: Article

References (27)

1. Southern E.M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98 (1975) 503-517
2. Botstein D., White R.L., Skolnick M., and Davis R.W. Construction of a genetic linkage map in man using restriction length polymorphisms. Am. J. Hum. Genet. 32 (1980) 314-331
3. Donis-Keller H., Green P., Helms C., Cartinhour S., Weiffenbach B., Stephens K., Keith T.P., Bowden D.W., Smith D.R., Lander E.S., et al. A genetic linkage map of the human genome. Cell 51 (1987) 319-337
4. Weber J.L., and May P.E. Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. Am. J. Hum. Genet. 44 (1989) 388-396
5. NIH/CEPH Collaborative Mapping Group. A comprehensive genetic linkage map of the human genome. Science 258 (1992) 148-162
6. Daly M.J., Rioux J.D., Schaffner S.F., Hudson T.J., and Lander E.S. High-resolution haplotype structure in the human genome. Nat. Genet. 29 (2001) 229-232
7. Reich D.E., Cargill M., Bolk S., Ireland J., Sabeti P.C., Richter D.J., Lavery T., Kouyoumjian R., Farhadian S.F., Ward R., and Lander E.S. Linkage disequilibrium in the human genome. Nature 411 (2001) 199-204
8. International HapMap Consortium. The International HapMap Project. Nature 426 (2003) 789-796
9. Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls. Nature 447 (2007) 661-678
10. Gusella J.F., Wexler N.S., Conneally P.M., Naylor S.L., Anderson M.A., Tanzi R.E., Watkins P.C., Ottina K., Wallace M.R., Sakaguchi A.Y., Young A.B., Shoulson I., Bonilla E., and Martin J.B. A polymorphic DNA marker genetically linked to Huntington's disease. Nature 306 (1983) 234-238
11. Schena M., Shalon D., Davis R.W., and Brown P.O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270 (1995) 467-470
12. Sanger F., Nicklen S., and Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74 (1977) 5463-5467
13. Eid J., Fehr A., Gray J., Luong K., Lyle J., Otto G., Peluso P., Rank D., Baybayan P., Bettman B., et al. Real-time DNA sequencing from single polymerase molecules. Science 323 (2009) 133-138
14. Monaco A.P., Neve R.L., Colletti-Feener C., Bertelson C.J., Kurnit D.M., and Kunkel L.M. Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy gene. Nature 323 (1986) 646-650
15. Kere J., Srivastava A.K., Montonen O., Zonana J., Thomas N., Ferguson B., Munoz F., Morgan D., Clarke A., Baybayan P., et al. X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nat. Genet. 13 (1996) 409-416
16. Taipale M., Kaminen N., Nopola-Hemmi J., Haltia T., Myllyluoma B., Lyytinen H., Muller K., Kaaranen M., Lindsberg P.J., Hannula-Jouppi K., et al. A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain. Proc. Natl. Acad. Sci. USA 100 (2003) 11553-11558
17. Kruglyak L., Daly M.J., Reeve-Daly M.P., and Lander E.S. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am. J. Hum. Genet. 58 (1996) 1347-1363
18. International Psoriasis Genetics Consortium. The International Psoriasis Genetics Study: assessing linkage to 14 candidate susceptibility loci in a cohort of 942 affected sib pairs. Am. J. Hum. Genet. 73 (2003) 430-437
19. Lander E.S., and Schork N.J. Genetic dissection of complex traits. Science 265 (1994) 2037-2048
20. Laitinen T., Polvi A., Rydman P., Vendelin J., Pulkkinen V., Salmikangas P., Mäkelä S., Rehn M., Pirskanen A., Rautanen A., et al. Characterization of a common susceptibility locus for asthma-related traits. Science 304 (2004) 300-304
21. Kruglyak L. Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat. Genet. 22 (1999) 139-144
22. Manolio T.A., Collins F.S., Cox N.J., Goldstein D.B., Hindorff L.A., Hunter D.J., McCarthy M.I., Ramos E.M., Cardon L.R., Chakravarti A., et al. Finding the missing heritability of complex diseases. Nature 461 (2009) 747-753
23. Weedon M.N., Lango H., Lindgren C.M., Wallace C., Evans D.M., Mangino M., Freathy R.M., Perry J.R., Stevens S., Hall A.S., et al. Genome-wide association analysis identifies 20 loci that influence adult height. Nat. Genet. 40 (2008) 575-583
24. Zwick M.E., Cutler D.J., and Chakravarti A. Patterns of genetic variation in Mendelian and complex traits. Annu. Rev. Genom. Hum. Genet. 1 (2000) 387-407
25. J.C. Roach, G. Glusman, A.F. Smit, C.D. Huff, R. Hubley, P.T. Shannon, L. Rowen, K.P. Pant, N. Goodman, M. Bamshad et al., Analysis of genetic inheritance in a family quartet by whole-genome sequencing, Science (Epub ahead of print).
26. Ng S.B., Turner E.H., Robertson P.D., Flygare S.D., Bigham A.W., Lee C., Shaffer T., Wong M., Bhattacharjee A., Eichler E.E., et al. Targeted capture and massively parallel sequencing of 12 human exomes. Nature 461 (2009) 272-276
27. Campanero M.R., Armstrong M.I., and Flemington E.K. CpG methylation as a mechanism for the regulation of E2F activity. Proc. Natl. Acad. Sci. USA 97 (2000) 6481-6486