Treatment of heart failure by a methanocarba derivative of adenosine monophosphate: Implication for a role of cardiac purinergic P2X receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 333, Issue 3, 2010, Pages 920-928

  Zhou, Si Yuan ^c   Mamdani, Mohammed ^c   Qanud, Khaled ^c   Shen, Jian Bing ^a   Pappano, Achilles J ^a   Santhosh Kumar, T ^b   Jacobson, Kenneth A ^b   Hintze, Thomas ^c   Recchia, Fabio A ^c,d   Liang, Bruce T ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

^d SCUOLA SUPERIORE SANT ANNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 (6 AMINO 2 CHLORO 9H PURIN 9 YL) 1 [PHOSPHORYLOXYMETHYL] BICYCLE[3.1.0]HEXANE 2,3 DIOL); ADENINE DERIVATIVE; ADENOSINE PHOSPHATE; CALSEQUESTRIN; CARDIOVASCULAR AGENT; MRS 2339; PURINERGIC P2X RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL OXYGEN SATURATION; ARTICLE; CONTROLLED STUDY; DIASTOLE; DOG; FEMALE; GENE OVEREXPRESSION; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART OUTPUT; HEART PACING; HEART PERFORMANCE; HYDROLYSIS; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SYSTOLE;

ADENOSINE MONOPHOSPHATE; ANIMALS; CARDIAC PACING, ARTIFICIAL; CARDIOMYOPATHY, DILATED; DOGS; HEART; HEART FAILURE; HEART FUNCTION TESTS; HEMODYNAMICS; INFUSIONS, INTRAVENOUS; MALE; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; RECEPTORS, PURINERGIC P2; TACHYCARDIA; VENTRICULAR FUNCTION, LEFT;

EID: 77952402525     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.164376     Document Type: Article

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