Metabonomics study of the protective effects of Lonicera japonica extract on acute liver injury in dimethylnitrosamine treated rats

Journal of Pharmaceutical and Biomedical Analysis

Volumn 53, Issue 1, 2010, Pages 98-102

  Sun, Changhai ^a,b   Teng, Yang ^a   Li, Guangzhi ^a   Yoshioka, Saburo ^b   Yokota, Junko ^b   Miyamura, Mitsuhiko ^b   Fang, Hongzhuang ^a   Zhang, Yu ^a  

^a JIAMUSI UNIVERSITY   (China)

^b KOCHI MEDICAL SCHOOL HOSPITAL   (Japan)

Author keywords

Dimethylnitrosamine (DMN); GC MS; Hepatic injury; Lonicera japonica extract (LJE); Metabonomics

Indexed keywords

8 AZAGUANINE; BIOLOGICAL MARKER; DIMETHYLNITROSAMINE; LONICERA JAPONICA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMOMETRIC ANALYSIS; CONTROLLED STUDY; HISTOPATHOLOGY; LIVER FIBROSIS; LIVER INJURY; LIVER PROTECTION; LONICERA JAPONICA; MALE; MASS FRAGMENTOGRAPHY; MULTIVARIATE ANALYSIS; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT; STAINING; WISTAR RAT;

ANIMALS; BIOMARKERS, PHARMACOLOGICAL; DIMETHYLNITROSAMINE; DRUG-INDUCED LIVER INJURY; DRUGS, CHINESE HERBAL; FIBROSIS; FLOWERS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LONICERA; METABOLOMICS; PHYTOTHERAPY; RATS; RATS, WISTAR; TIME FACTORS;

EID: 77952320210     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.03.015     Document Type: Article

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