Application of nuclear magnetic resonance spectroscopy combined with principal component analysis in detecting inborn errors of metabolism using blood spots: A metabonomic approach

Analytica Chimica Acta

Volumn 511, Issue 2, 2004, Pages 303-312

  Constantinou, M A ^a   Papakonstantinou, E ^b   Benaki, D ^a   Spraul, M ^c   Shulpis, K ^b   Koupparis, M A ^a   Mikros, E ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b AGHIA SOPHIA CHILDREN S HOSPITAL   (Greece)

^c Bruker Analytik GmbH   (Germany)

Author keywords

Blood spots; Inborn errors of metabolism (IEM); Maple syrup urine disease (MSUD); Nuclear magnetic resonance (NMR) spectroscopy; Phenylketonuria (PKU); Principal component analysis (PCA)

Indexed keywords

DIAGNOSIS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SPECTRUM ANALYSIS;

BLOOD SPOT; FILTER PAPERS;

BLOOD;

ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DIAGNOSTIC VALUE; HUMAN; INBORN ERROR OF METABOLISM; MAPLE SYRUP URINE DISEASE; MASS SCREENING; NEWBORN; PHENYLKETONURIA; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ACER;

EID: 2342520064     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2004.02.012     Document Type: Article

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