Intrahepatic cholangiocarcinoma and hepatocellular carcinoma: differential diagnosis with contrast-enhanced ultrasound

European Radiology

Volumn 20, Issue 3, 2010, Pages 743-753

  Chen, Li Da ^a   Xu, Hui Xiong ^a   Xie, Xiao Yan ^a   Xie, Xiao Hua ^a   Xu, Zuo Feng ^a   Liu, Guang Jian ^a   Wang, Zhu ^a   Lin, Man Xia ^a   Lu, Ming De ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Characterisation; Contrast enhanced ultrasound; Differential diagnosis; Hepatocellular carcinoma; Intrahepatic cholangiocarcinoma

Indexed keywords

SONOVUE; CONTRAST AGENT BR1; CONTRAST MEDIUM; DIAGNOSTIC AGENT; PHOSPHOLIPID; SULFUR HEXAFLUORIDE;

ADULT; AGED; ARTICLE; BILE DUCT CARCINOMA; CANCER DIAGNOSIS; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; ECHOGRAPHY; FEMALE; HUMAN; IMAGE ANALYSIS; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; PERFORMANCE MEASUREMENT SYSTEM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; ADOLESCENT; COMPARATIVE STUDY; LIVER TUMOR; METHODOLOGY; MIDDLE AGED; REPRODUCIBILITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; CHOLANGIOCARCINOMA; CONTRAST MEDIA; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; PHOSPHOLIPIDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SULFUR HEXAFLUORIDE; ULTRASONOGRAPHY; YOUNG ADULT;

EID: 77952307211     PISSN: 09387994     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00330-009-1599-8     Document Type: Article

References (33)

1. Llovet JM, Bruix J (2008) Novel advancements in the management of hepatocellular carcinoma in 2008. J Hepatol 48(Suppl 1):S20-S37
2. Sangiovanni A, Del Ninno E, Fasani P et al (2004) Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance. Gastroenterology 126:1005-1014
3. Davila JA, El-Serag HB (2002) Cholangiocarcinoma: the "other" liver cancer on the rise. Am J Gastroenterol 97:3199-3200
4. Khan SA, Thomas HC, Davidson BR et al (2005) Cholangiocarcinoma. Lancet 366:1303-1314
5. Khan SA, Davidson BR, Goldin R et al (2002) Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document. Gut 51(Suppl 6):vi1-vi9
6. Ng IO (1998) Prognostic significance of pathological and biological factors in hepatocellular carcinoma. J Gastroenterol Hepatol 13:666-670
7. Wibulpolprasert B, Dhiensiri T (1992) Peripheral cholangiocarcinoma: sonographic evaluation. J Clin Ultrasound 20:303-314
8. Colli A, Cocciolo M, Mumoli N et al (1998) Peripheral intrahepatic cholangiocarcinoma: ultrasound findings and differential diagnosis from hepatocellular carcinoma. Eur J Ultrasound 7:93-99
9. Choi BI, Lee JM, Han JK (2004) Imaging of intrahepatic and hilar cholangiocarcinoma. Abdom Imaging 29:548-557
10. Xu HX, Liu GJ, Lu MD et al (2006) Characterization of small focal liver lesions using real-time contrast-enhanced sonography: diagnostic performance analysis in 200 patients. J Ultrasound Med 25:349-361
11. Xu HX, Lu MD, Liu GJ et al (2006) Imaging of peripheral cholangiocarcinoma with low-mechanical index contrast-enhanced sonography and SonoVue: initial experience. J Ultrasound Med 25:23-33
12. Furuse J, Nagase M, Ishii H et al (2003) Contrast enhancement patterns of hepatic tumours during the vascular phase using coded harmonic imaging and Levovist to differentiate hepatocellular carcinoma from other focal lesions. Br J Radiol 76:385-392
13. Claudon M, Cosgrove D, Albrecht T et al (2008) Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS)-update 2008. Ultraschall Med 29:28-44
14. Liu GJ, Xu HX, Lu MD et al (2007) Correlation between enhancement pattern of hepatocellular carcinoma on real-time contrast-enhanced ultrasound and tumour cellular differentiation on histopathology. Br J Radiol 80:321-330
15. Bruix J, Sherman M (2005) Management of hepatocellular carcinoma. Hepatology 42:1208-1236
16. Quaia E, Calliada F, Bertolotto M et al (2004) Characterization of focal liver lesions with contrast-specific US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence. Radiology 232:420-430
17. Xu HX, Liu GJ, Lu MD et al (2006) Characterization of focal liver lesions using contrast-enhanced sonography with a low mechanical index mode and a sulfur hexafluoride-filled microbubble contrast agent. J Clin Ultrasound 34:261-272
18. Dietrich CF (2004) Characterisation of focal liver lesions with contrast enhanced ultrasonography. Eur J Radiol 51(Suppl):S9-S17
19. Nicolau C, Bru C (2004) Focal liver lesions: evaluation with contrast-enhanced ultrasonography. Abdom Imaging 29:348-359
20. von Herbay A, Vogt C, Willers R et al (2004) Real-time imaging with the sonographic contrast agent SonoVue: differentiation between benign and malignant hepatic lesions. J Ultrasound Med 23:1557-1568 (Pubitemid 39586861)
21. Chen LD, Xu HX, Xie XY et al (2008) Enhancement patterns of intrahepatic cholangiocarcinoma: comparison between contrast-enhanced ultrasound and contrast-enhanced CT. Br J Radiol 81:881-889
22. Ros PR, Buck JL, Goodman ZD et al (1988) Intrahepatic cholangiocarcinoma: radiologic-pathologic correlation. Radiology 167:689-693
23. Lim JH (2003) Cholangiocarcinoma: morphologic classification according to growth pattern and imaging findings. AJR Am J Roentgenol 181:819-827
24. Lim JH, Park CK (2004) Pathology of cholangiocarcinoma. Abdom Imaging 29:540-547
25. Han JK, Choi BI, Kim AY et al (2002) Cholangiocarcinoma: pictorial essay of CT and cholangiographic findings. Radiographics 22:173-187
26. Ueda K, Terada T, Nakanuma Y et al (1992) Vascular supply in adenomatous hyperplasia of the liver and hepatocellular carcinoma: a morphometric study. Hum Pathol 23:619-626
27. Yoshida Y, Imai Y, Murakami T et al (1999) Intrahepatic cholangiocarcinoma with marked hypervascularity. Abdom Imaging 24:66-68
28. Valls C, Guma A, Puig I et al (2000) Intrahepatic peripheral cholangiocarcinoma: CT evaluation. Abdom Imaging 25:490-496
29. Klein D, Jenett M, Gassel HJ et al (2004) Quantitative dynamic contrastenhanced sonography of hepatic tumors. Eur Radiol 14:1082-1091
30. Celik H, Ozdemir H, Yucel C et al (2005) Characterization of hyperechoic focal liver lesions: quantitative evaluation with pulse inversion harmonic imaging in the late phase of levovist. J Ultrasound Med 24:39-47
31. Li J, Dong BW, Yu XL et al (2005) Time-intensity-based quantification of vascularity with single-level dynamic contrast-enhanced ultrasonography: a pilot animal study. J Ultrasound Med 24:975-983
32. Hayashi M, Matsui O, Ueda K et al (2002) Progression to hypervascular hepatocellular carcinoma: correlation with intranodular blood supply evaluated with CT during intraarterial injection of contrast material. Radiology 225:143-149
33. Kim TK, Jang HJ, Burns PN et al (2008) Focal nodular hyperplasia and hepatic adenoma: differentiation with low-mechanical-index contrastenhanced sonography. AJR Am J Roentgenol 190:58-66