NPPB structure-specifically activates TRPA1 channels

Biochemical Pharmacology

Volumn 80, Issue 1, 2010, Pages 113-121

  Liu, Kun ^a   Samuel, Manoj ^a   Ho, Melisa ^a   Harrison, Richard K ^a   Paslay, Jeff W ^a  

^a PFIZER INC   (United States)

Author keywords

Covalent modification; Mutagenesis; NPPB; Structure specific modification; TRPA1 channels

Indexed keywords

2 (BENZYLAMINO) 4 NITROBENZOIC ACID; 2 AMINO 5 NITROBENZOIC ACID; 4 (3 PHENYLPROPYLAMINO)BENZOIC ACID; 5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; 5 NITRO 2 (PHENETHYLAMINO)BENZAMIDE; 5 NITRO 2 (PHENETHYLAMINO)BENZOIC ACID; 5 NITRO 2 (PHENETHYLAMINO)BENZONITRILE; 5 NITRO 2 (PHENYLAMINO)BENZOIC ACID; 5 NITRO 2 PROPIONAMIDOBENZOIC ACID; BENZOIC ACID DERIVATIVE; CALCIUM ION; CAPSAICIN; CHLORIDE CHANNEL BLOCKING AGENT; CYSTEINE; MENTHOL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL STRAIN HEK293; CHEMICAL REACTION; CHEMICAL STRUCTURE; HUMAN; HUMAN CELL; IMAGING; INFLAMMATION; MAMMAL; MUTAGENESIS; MUTATION; NOCICEPTION; NUCLEOTIDE SEQUENCE; PAIN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION;

CALCIUM CHANNELS; CELL LINE; HUMANS; ISOTHIOCYANATES; KIDNEY; MENTHOL; MUTAGENESIS; NERVE TISSUE PROTEINS; NEURONS; NITROBENZOATES; PAIN; PATCH-CLAMP TECHNIQUES; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 77952289412     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.03.005     Document Type: Article

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