Rb+ efflux assay for assessment of non-selective cation channel activities

Assay and Drug Development Technologies

Volumn 8, Issue 3, 2010, Pages 375-383

  Liu, Kun ^a   Samuel, Manoj ^a   Harrison, Richard K ^a   Paslay, Jeff W ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; ALLYL ISOTHIOCYANATE; ANTHRANILIC ACID DERIVATIVE; CALCIUM ION; CARBACHOL; HC 030031; N (4 AMYLCINNAMOYL)ANTHRANILIC ACID; RUBIDIUM ION; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT; UNCLASSIFIED DRUG; BUFFER; CALCIUM CHANNEL; CATION; ION CHANNEL; NERVE PROTEIN; RUBIDIUM; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPA1 PROTEIN, HUMAN; TRPC6 PROTEIN, HUMAN;

ARTICLE; CALCIUM TRANSPORT; CELL ASSAY; CELL STRAIN HEK293; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HIGH THROUGHPUT SCREENING; ION PERMEABILITY; ION TRANSPORT; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; CELL LINE; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; HUMAN; KINETICS; METABOLISM; METHODOLOGY; PATCH CLAMP;

BUFFERS; CALCIUM CHANNELS; CATIONS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HUMANS; ION CHANNELS; KINETICS; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; RUBIDIUM; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPC CATION CHANNELS;

EID: 77952288915     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2009.0243     Document Type: Article

References (25)

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