Fluoxetine induces apoptosis in ovarian carcinoma cell line OVCAR-3 Through reactive oxygen species-dependent activation of nuclear factor-κB

Basic and Clinical Pharmacology and Toxicology

Volumn 106, Issue 6, 2010, Pages 446-453

  Lee, Chung Soo ^a   Kim, Yun Jeong ^a   Jang, Eun Ra ^a   Kim, Wonyong ^a   Myung, Soon Chul ^b  

^a Chung Ang University   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 TERT BUTYLPHENYLSULFONYL) 2 PROPENENITRILE; ACETYLCYSTEINE; CASPASE 3; CYCLOSPORIN A; CYTOCHROME C; FLUOXETINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TROLOX C; SEROTONIN UPTAKE INHIBITOR;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING SITE; CELL DEATH; CELL STRAIN; CELL STRAIN OVCAR 3; CELL STRAIN SK OV 3; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; UPREGULATION; DRUG EFFECTS; FEMALE; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; OVARIAN NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; CASPASE 3; CELL DEATH; CELL LINE, TUMOR; CYTOCHROMES C; FEMALE; FLUOXETINE; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NF-KAPPA B; OVARIAN NEOPLASMS; REACTIVE OXYGEN SPECIES; SEROTONIN UPTAKE INHIBITORS;

EID: 77952266202     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2009.00509.x     Document Type: Article

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