Neuronal cell death induced by antidepressants: Lack of correlation with Egr-1, NF-κB and extracellular signal-regulated protein kinase activation

Biochemical Pharmacology

Volumn 63, Issue 8, 2002, Pages 1507-1516

  Bartholomä, Pia ^a   Erlandsson, Nina ^a   Kaufmann, Katrin ^a   Rössler, Oliver G ^a   Baumann, Bernd ^b   Wirth, Thomas ^b   Giehl, Klaus M ^a   Thiel, Gerald ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

Antidepressants; Egr 1; Extracellular signal regulated kinase; Neuronal cell death; NF B; Sphingosine 1 phosphate

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; AMITRIPTYLINE; CYCLIC AMP; DESIPRAMINE; EARLY GROWTH RESPONSE FACTOR 1; FLUOXETINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SEROTONIN UPTAKE INHIBITOR; SPHINGOSINE 1 PHOSPHATE; TRICYCLIC ANTIDEPRESSANT AGENT;

ARTICLE; CELL LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; HUMAN; HUMAN CELL; NERVE CELL; NERVE CELL NECROSIS; NEUROTOXICITY; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

AMITRIPTYLINE; ANIMALS; ANTIDEPRESSIVE AGENTS; CELL DEATH; CYCLIC AMP; DESIPRAMINE; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; FLUOXETINE; I-KAPPA B PROTEINS; IMMEDIATE-EARLY PROTEINS; LYSOPHOSPHOLIPIDS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; NF-KAPPA B; OXIDATION-REDUCTION; PC12 CELLS; PHOSPHORYLATION; RATS; SPHINGOSINE; TRANSCRIPTION FACTORS;

EID: 0037091050     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)00882-1     Document Type: Article

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