Contribution of B7RP-1/ICOS co-stimulation to lethal acute GVHD

Pediatric Transplantation

Volumn 14, Issue 4, 2010, Pages 540-548

  Fujimura, Junya ^a   Takeda, Kazuyoshi ^a   Kaduka, Yuki ^a   Saito, Masahoro ^a   Akiba, Hisaya ^a   Yagita, Hideo ^a   Yamashiro, Yuichiro ^a   Shimizu, Toshiaki ^a   Okumura, Ko ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone marrow transplantation; GVHD; ICOS; T lymphocytes

Indexed keywords

B7 ANTIGEN; B7 ANTIGEN RELATED PROTEIN 1; B7 RELATED PROTEIN 1 ANTIBODY; CD28 ANTIGEN; INDUCIBLE COSTIMULATOR; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; ALLOANTIGEN; GAMMA INTERFERON; ICOS PROTEIN, MOUSE; INDUCIBLE T CELL COSTIMULATOR; INDUCIBLE T CELL COSTIMULATOR LIGAND; T LYMPHOCYTE ANTIGEN; TRANSACTIVATOR PROTEIN;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; FEMALE; GRAFT RECIPIENT; GRAFT VERSUS HOST REACTION; LETHALITY; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SPLEEN CELL; T CELL DEPLETION; WILD TYPE; ALLOTRANSPLANTATION; ANIMAL; BLOOD; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CYTOLOGY; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOLOGY; METABOLISM; MORTALITY; NONPARAMETRIC TEST; SPLEEN;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD80; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BONE MARROW TRANSPLANTATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GRAFT REJECTION; GRAFT SURVIVAL; GRAFT VS HOST DISEASE; INDUCIBLE T-CELL CO-STIMULATOR LIGAND; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; INTERFERON-GAMMA; ISOANTIGENS; MICE; MICE, INBRED C57BL; SPLEEN; STATISTICS, NONPARAMETRIC; TRANS-ACTIVATORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 77952260425     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2009.01279.x     Document Type: Article

References (46)

1. Thomas ED. Karnofsky memorial lecture. Marrow transplantation for malignant disease. J Clin Oncol 1983 : 1 : 517 531.
2. Bortin MM, Rimm AA. Increasing utilization of bone marrow transplantation. Transplantation 1986 : 42 : 229 234.
3. Herve P, Cahn JY, Beatty PG. Graft-versus-host disease after bone marrow transplantation from donors other than HLA-identical siblings. In : Busakoff SJ, Deeg HJ, Ferrara J, Atkins K, eds. Graft-Versus-Host Disease.
4. Wagner JE, Donnenberg AD, Noga SJ, et al. Lymphocyte depletion of donor bone marrow by counterflow centrifugal elutriation: Results of a phase I clinical trial. Blood 1988 : 72 : 1168 1176.
5. Young JW, Papadopoulos EB, Cunningham I, et al. T-cell-depleted allogeneic bone marrow transplantation in adults with nonlymphocytic leukemia in first remission. Blood 1992 : 79 : 3380 3387.
6. Filipovich AH, Vallera D, McGlave P, et al. T cell depletion with anti-CD5 immunotoxin in histocompatible bone marrow transplantation. The correlation between residual CD5 negative T cell and subsequent graft-versus-host disease. Transplantation 1990 : 50 : 410 414.
7. Hale G, Cobbold S, Waldmann H. T cell depletion with CAMPATH-1 in allogeneic bone marrow transplantation. Transplantation 1988 : 45 : 753 758.
8. Soiffer RJ, Fairclough D, Robertson M, et al. CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission. Blood 1997 : 89 : 3039 3047.
9. Marmont AM, Horowitz MM, Gale RP, et al. T cell depletion of HLA-identical transplantation in leukemia. Blood 1991 : 78 : 2120 2130.
10. Goldman JM, Gale RP, Horowitz MM, et al. Bone marrow transplantation for chronic myelogenous leukemia in chronic phase: Increased risk for relapse associated T-cell depletion. Ann Intern Med 1988 : 108 : 806 814.
11. Mitsuyasu RT, Champlin RE, Gale RP, et al. Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease. A prospective, randomized, double-blind trial. Ann Intern Med 1986 : 105 : 20 26.
12. Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990 : 248 : 1349 1356.
13. Lenschow DJ, Walunas TL, Bluestone J. CD28/B7 system of T cell costimulation. Annu Rev Immunol 1996 : 14 : 233 258.
14. Yu XZ, Martin PJ, Anasetti C. Role of CD28 in acute graft-versus-host- disease. Blood 1998 : 92 : 2963 2970.
15. Speiser DE, Bachmann MF, Shahinian A, et al. Acute graft-versus-host disease without costimulation via CD28. Transplantation 1997 : 63 : 1042 1044.
16. Via CS, Rus V, Nguyen P, et al. Differential effect of CTLA4Ig on murine graft-versus-host disease (GVHD) development. J Immunol 1996 : 157 : 4258 4267.
17. Wallance PM, Johnson JS, MacMaster JF, et al. CTLA4Ig treatment ameliorates the lethality of murine graft-versus-host disease across major histocompatibility complex barriers. Transplantation 1994 : 58 : 602 610.
18. Hutloff A, Dittrich AM, Beier KC, et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 1999 : 397 : 263 266.
19. Iwai H, Abe M, Hirose S, et al. Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis. J Immunol 2003 : 171 : 2848 2854.
20. Mages HW, Hutloff A, Heuck C, et al. Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand. Eur J Immunol 2000 : 30 : 1040 1047.
21. Yoshinaga SK, Whoriskey JS, Khare SD, et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature 1999 : 402 : 827 832.
22. Yoshinaga SK, Zhang M, Pistillo J, et al. Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS. Int Immunol 2000 : 12 : 1439 1447.
23. Ling V, Wu PW, Finnerty HF, et al. Cutting edge: Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor. J Immunol 2000 : 164 : 1653 1657.
24. Brodie D, Collins AV, laboni A, et al. LICOS, a primordial costimulatory ligand? Curr Biol 2000 : 10 : 333 336.
25. Ozkaynak E, Gao W, Shemmerin N, et al. Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection. Nat Immunol 2001 : 2 : 591 596.
26. Guillonneau C, Aubry V, Renaudin K, et al. Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade. Transplantation 2005 : 80 : 546 554.
27. Kashizuka H, Sho M, Nomi T, et al. Role of ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection. Transplantation 2005 : 79 : 1045 1050.
28. Harada H, Salama AD, Sho M, et al. The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. J Clin Invest 2003 : 112 : 234 243.
29. Ogawa S, Nagamatsu G, Watanabe M, et al. Opposing effects of anti-activation-inducible lymphocyte-immunomodulatory molecule/inducible costimulator antibody on the development of acute versus chronic graft-versus-host disease. J Immunol 2001 : 167 : 5741 5748.
30. Taylor PA, Panoskaltsis-Mortari A, Freeman GJ, et al. Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM). Blood 2005 : 105 : 3372 3380.
31. Hubbard VM, Eng JM, Ramirez-Montagut T, et al. Absence of inducible costimulator on alloreactive T cells reduces graft versus host disease and induces Th2 deviation. Blood 2005 : 106 : 3285 3292.
32. Yu XZ, Liang Y, Nurieva RI, et al. Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells. J Immunol 2006 : 176 : 7394 7401.
33. Totsuka T, Kanai T, Iiyama R, et al. Ameliorating effect of anti-inducible costimulator monoclonal antibody in murine model of chronic colitis. Gastroenterology 2003 : 124 : 410 421. (Pubitemid 36169258)
34. Tsukada N, Akiba H, Kobata T, et al. Blockade of CD134 (OX40)-CD134L interaction ameliorate lethal acute graft-versus-host disease in murine model of allogeneic bone marrow transplantation. Blood 2000 : 95 : 2434 2439.
35. Allen RD, Staley TA, Sidman CL. Differential cytokine expression in acute and chronic murine graft-versus-host disease. Eur J Immunol 1993 : 23 : 333 337.
36. Tanaka J, Imamura M, Kasai M, et al. The important balance between cytokine derived from type 1 and 2 helper T cells in the control of graft-versus-host disease. Bone Marrow Transplant 1997 : 19 : 571 576.
37. Knulst AC, Tibbe GJM, Bril-Bazuin C, et al. Cytokine detection and modulation in acute graft vs. host disease in mice. Mediators Inflamm 1994 : 3 : 33 40.
38. Watanabe M, Watanabe S, Hara Y, et al. ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling. J Immunol 2005 : 174 : 1989 1996.
39. Wallin JJ, Liang L, Bakardjiev A, et al. Enhancement of CD8+ T cell responses by ICOS/B7h costimulation. J Immunol 2001 : 167 : 132 139.
40. Liu X, Bai XF, Wen J, et al. B7h costimulates clonal expansion of, and cognate destruction of tumor cells by, CD8+ T lymphocytes in vivo. J Exp Med 2001 : 194 : 1339 1348.
41. Bertram EM, Tafuri A, Shahinian A, et al. Role of ICOS versus CD28 in antiviral immunity. Eur J Immunol 2002 : 32 : 3376 3385.
42. Watanabe M, Hara Y, Tanabe K, et al. A distinct role for ICOS-mediated co-stimulatory signaling in CD4+ and CD8+ T cell subsets. Int Immunol 2005 : 17 : 269 278.
43. Schenk AD, Gorbacheva V, Rabant M, et al. Effector functions of donor-reactive CD8 memory T cells are dependent on ICOS induced during division in cardiac grafts. Am J Transplant 2009 : 9 : 64 73.
44. Rothstein DM, Sayegh MH. T-cell costimulatory pathways in allograft rejection and tolerance. Immunol Rev 2003 : 196 : 85 108.
45. Sabbagh L, Snell LM, Watts TH. TNF family ligands define niches for T cell memory. Trends Immunol 2007 : 28 : 333 339.
46. Shuford WW, Klussman K, Tritchler DD, et al. 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J Exp Med 1997 : 186 : 47 55.