Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c

Journal of Controlled Release

Volumn 143, Issue 3, 2010, Pages 350-358

  Oliveira, Hugo ^a,b   Fernandez, Ramon ^a   Pires, Liliana R ^a   Martins, M Cristina L ^a   Simões, Sérgio ^c,d   Barbosa, Mário A ^a,b   Pêgo, Ana P ^a  

^a INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Nanoparticle; Non viral; Peripheral nervous system; Regenerative medicine; Targeted

Indexed keywords

BIFUNCTIONAL; CELL LINES; CELLULAR INTERNALIZATION; COMPLEX CORES; COMPLEX FORMULATIONS; COMPLEX SURFACE; DORSAL ROOT GANGLIA; EFFICIENT SYSTEMS; MULTICOMPONENTS; NEURONAL CELL; NEUROTROPHIC FACTORS; NON-VIRAL GENE DELIVERY; NONVIRAL; PERIPHERAL NERVOUS SYSTEM; PERIPHERAL NEUROPATHY; POLYETHYLENEIMINE; PRIMARY CULTURE; REGENERATIVE MEDICINE; SELF-ASSEMBLED; STARTING MATERIALS; TARGETED GENE DELIVERY; TERNARY COMPLEX; TERNARY VECTORS; TETANUS TOXIN;

ABERRATIONS; CELL CULTURE; ETHYLENE; GENE TRANSFER; NANOPARTICLES; NEURONS; NITROGEN COMPOUNDS; NUCLEIC ACIDS; POLYETHYLENE OXIDES; ZETA POTENTIAL;

POLYETHYLENE GLYCOLS;

DNA; MACROGOL; NEUROTROPHIC FACTOR; POLYETHYLENEIMINE; TETANUS TOXIN; TETANUS TOXIN FRAGMENT C; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CHEMICAL MODIFICATION; CONTROLLED STUDY; DNA PROTEIN COMPLEX; EMBRYO; FEMALE; GENE TRANSFER; GENETIC TRANSFECTION; INTERNALIZATION; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PERIPHERAL NERVOUS SYSTEM; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; RAT; SENSORY NERVE CELL; SPINAL GANGLION; ZETA POTENTIAL;

ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; DNA; FEMALE; IMINES; MICE; NEURONS; NIH 3T3 CELLS; PEPTIDE FRAGMENTS; PERIPHERAL NERVOUS SYSTEM; PLASMIDS; POLYETHYLENES; RATS; RATS, WISTAR; TETANUS TOXIN; TRANSFECTION;

EID: 77952239026     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.01.018     Document Type: Article

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